Q2YQL5 (CBID_BRUA2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative cobalt-precorrin-6A synthase [deacetylating]
EC=2.1.1.-

Gene names

Name:	cbiD
Ordered Locus Names:	BAB1_1318

Organism

Brucella abortus (strain 2308) [Complete proteome] [HAMAP]

Taxonomic identifier

359391 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella abortus

Protein attributes

Sequence length	368 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May catalyze the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A By similarity. HAMAP-Rule MF_00787
Pathway	Cofactor biosynthesis; adenosylcobalamin biosynthesis; cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 6/10. HAMAP-Rule MF_00787
Sequence similarities	Belongs to the CbiD family.

Ontologies

Keywords
Biological process	Cobalamin biosynthesis
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cobalamin biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway corrin biosynthetic process Inferred from electronic annotation. Source: HAMAP methylation Inferred from electronic annotation. Source: GOC
Molecular_function	cobalamin-transporting ATPase activity Inferred from electronic annotation. Source: HAMAP methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 368	368	Putative cobalt-precorrin-6A synthase [deacetylating] HAMAP-Rule MF_00787		PRO_0000257749

Sequences

	Sequence		Length	Mass (Da)
	Q2YQL5 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 5F3040A081BDFFDF	FASTA	368	38,530
	10 20 30 40 50 60 MNDETTPANK NPEKAELRCG WTTGACATAA TKAALTALIT GEFPDPVGII LPKGEVPYFQ 70 80 90 100 110 120 LAYEGLGEGY AMAGIVKDAG DDPDVTHGAT IISTVYPAPP GTGIIFRAGE GVGTVTREGL 130 140 150 160 170 180 AIPPGEAAIN PVPRRMMTEI CEAICAEYGL PADLVITISV PGGEEIAQKT WNPRLGIIGG 190 200 210 220 230 240 ISILGTTGVV HPFSCSAWIH SIHRGIDVAR AAGQKHVLGA TGSTSEDAAQ ALYNLPDFAI 250 260 270 280 290 300 LDMGDFAGGV LKYLREHPID RLTIAGGFAK LTKLAQGALD LHSSRSQVDK GFLWQIAERA 310 320 330 340 350 360 GAPAGMKERI LLANTAMEVL ELTQSIGIDI AGPIALEARQ TALKTLRGAP VEVEIIVTDR KGNILARV

References

[1]

"Whole-genome analyses of speciation events in pathogenic Brucellae." Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E. Infect. Immun. 73:8353-8361(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 2308.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM040264 Genomic DNA. Translation: CAJ11274.1.
RefSeq	YP_414698.1. NC_007618.1.
3D structure databases
ProteinModelPortal	Q2YQL5.
ModBase	Search...
Protein-protein interaction databases
STRING	359391.BAB1_1318.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAJ11274; CAJ11274; BAB1_1318.
GeneID	3788641.
KEGG	bmf:BAB1_1318.
PATRIC	17845613. VBIBruMel86222_1371.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1903.
HOGENOM	HOG000009126.
KO	K02188.
OMA	ASEDTMR.
ProtClustDB	PRK00075.
Enzyme and pathway databases
BioCyc	BMEL359391:GJOQ-1345-MONOMER.
UniPathway	UPA00148; UER00227.
Family and domain databases
HAMAP	MF_00787. CbiD.
InterPro	IPR002748. Cbl_biosynth_CbiD. [Graphical view]
Pfam	PF01888. CbiD. 1 hit. [Graphical view]
PIRSF	PIRSF026782. CbiD. 1 hit.
SUPFAM	SSF111342. Cbl_biosynth_CbiD. 1 hit.
TIGRFAMs	TIGR00312. cbiD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CBID_BRUA2

Accession

Primary (citable) accession number: Q2YQL5

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	February 7, 2006
Last modified:	May 1, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program