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Q2YQ23 (NQOR_BRUA2) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
NAD(P)H dehydrogenase (quinone)

EC=1.6.5.2
Alternative name(s):
Flavoprotein WrbA
NAD(P)H:quinone oxidoreductase
Short name=NQO
Gene names
Ordered Locus Names:BAB1_1070
OrganismBrucella abortus (strain 2308) [Complete proteome] [HAMAP]
Taxonomic identifier359391 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length199 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

NAD(P)H + a quinone = NAD(P)+ + a hydroquinone. HAMAP-Rule MF_01017

Cofactor

Binds 1 FMN per monomer By similarity. HAMAP-Rule MF_01017

Sequence similarities

Belongs to the WrbA family.

Contains 1 flavodoxin-like domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 199199NAD(P)H dehydrogenase (quinone) HAMAP-Rule MF_01017
PRO_0000291007

Regions

Domain4 – 190187Flavodoxin-like
Nucleotide binding10 – 145FMN By similarity
Nucleotide binding110 – 16253FMN By similarity

Sites

Binding site121NAD(P) By similarity
Binding site981Substrate By similarity
Binding site1341FMN By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2YQ23 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: 1E70DC2A51E5A676

FASTA19921,442
        10         20         30         40         50         60 
MVKMLVLYYS AYGYMEQMAK AAAEGAREGG AEVTLKRVPE LVPEEVAKAS HYKIDQEVPI 

        70         80         90        100        110        120 
ATPGELADYD AIIIGTATRY GMMASQMKNF LDQTGGLWAK GALINKVGSV MVSTATQHGG 

       130        140        150        160        170        180 
AELALISTQW QMQHHGMIIV PLSYAYREQM GNDVVRGGAP YGMTTTADGD GSRQPSAQEL 

       190 
DGARFQGRRV AEITAKLHG 

« Hide

References

[1]"Whole-genome analyses of speciation events in pathogenic Brucellae."
Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.
Infect. Immun. 73:8353-8361(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 2308.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM040264 Genomic DNA. Translation: CAJ11026.1.
RefSeqYP_414473.1. NC_007618.1.

3D structure databases

ProteinModelPortalQ2YQ23.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING359391.BAB1_1070.

Proteomic databases

PRIDEQ2YQ23.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ11026; CAJ11026; BAB1_1070.
GeneID3787724.
KEGGbmf:BAB1_1070.
PATRIC17845082. VBIBruMel86222_1113.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0655.
HOGENOMHOG000030539.
KOK03809.
OMAQMKLDEV.
OrthoDBEOG6384K0.
ProtClustDBPRK03767.

Enzyme and pathway databases

BioCycBABO359391:GKDV-1089-MONOMER.
BMEL359391:GJOQ-1089-MONOMER.

Family and domain databases

HAMAPMF_01017. NQOR.
InterProIPR008254. Flavodoxin/NO_synth.
IPR010089. Flavoprotein_WrbA.
IPR005025. FMN_Rdtase-like.
[Graphical view]
PfamPF03358. FMN_red. 1 hit.
[Graphical view]
TIGRFAMsTIGR01755. flav_wrbA. 1 hit.
PROSITEPS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNQOR_BRUA2
AccessionPrimary (citable) accession number: Q2YQ23
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: February 7, 2006
Last modified: February 19, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella abortus strain 2308

Brucella abortus (strain 2308): entries and gene names