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Q2YQ23

- NQOR_BRUA2

UniProt

Q2YQ23 - NQOR_BRUA2

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Protein
NAD(P)H dehydrogenase (quinone)
Gene
BAB1_1070
Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

NAD(P)H + a quinone = NAD(P)+ + a hydroquinone.UniRule annotation

Cofactori

Binds 1 FMN per monomer By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei12 – 121NAD(P) By similarity
Binding sitei98 – 981Substrate By similarity
Binding sitei134 – 1341FMN By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 145FMN By similarity
Nucleotide bindingi110 – 16253FMN By similarity
Add
BLAST

GO - Molecular functioni

  1. FMN binding Source: InterPro
  2. NAD binding Source: UniProtKB-HAMAP
  3. NAD(P)H dehydrogenase (quinone) activity Source: UniProtKB-HAMAP
  4. NADP binding Source: UniProtKB-HAMAP
  5. flavin adenine dinucleotide binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. negative regulation of transcription, DNA-templated Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Flavoprotein, FMN, NAD, NADP, Nucleotide-binding

Enzyme and pathway databases

BioCyciBABO359391:GKDV-1089-MONOMER.
BMEL359391:GJOQ-1089-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
NAD(P)H dehydrogenase (quinone) (EC:1.6.5.2)
Alternative name(s):
Flavoprotein WrbA
NAD(P)H:quinone oxidoreductase
Short name:
NQO
Gene namesi
Ordered Locus Names:BAB1_1070
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 199199NAD(P)H dehydrogenase (quinone)UniRule annotation
PRO_0000291007Add
BLAST

Proteomic databases

PRIDEiQ2YQ23.

Interactioni

Protein-protein interaction databases

STRINGi359391.BAB1_1070.

Structurei

3D structure databases

ProteinModelPortaliQ2YQ23.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 190187Flavodoxin-like
Add
BLAST

Sequence similaritiesi

Belongs to the WrbA family.

Phylogenomic databases

eggNOGiCOG0655.
HOGENOMiHOG000030539.
KOiK03809.
OMAiYGHVESM.
OrthoDBiEOG6384K0.

Family and domain databases

Gene3Di3.40.50.360. 1 hit.
HAMAPiMF_01017. NQOR.
InterProiIPR008254. Flavodoxin/NO_synth.
IPR029039. Flavoprotein-like.
IPR010089. Flavoprotein_WrbA.
IPR005025. FMN_Rdtase-like.
[Graphical view]
PfamiPF03358. FMN_red. 1 hit.
[Graphical view]
SUPFAMiSSF52218. SSF52218. 1 hit.
TIGRFAMsiTIGR01755. flav_wrbA. 1 hit.
PROSITEiPS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2YQ23-1 [UniParc]FASTAAdd to Basket

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MVKMLVLYYS AYGYMEQMAK AAAEGAREGG AEVTLKRVPE LVPEEVAKAS    50
HYKIDQEVPI ATPGELADYD AIIIGTATRY GMMASQMKNF LDQTGGLWAK 100
GALINKVGSV MVSTATQHGG AELALISTQW QMQHHGMIIV PLSYAYREQM 150
GNDVVRGGAP YGMTTTADGD GSRQPSAQEL DGARFQGRRV AEITAKLHG 199
Length:199
Mass (Da):21,442
Last modified:February 7, 2006 - v1
Checksum:i1E70DC2A51E5A676
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040264 Genomic DNA. Translation: CAJ11026.1.
RefSeqiYP_414473.1. NC_007618.1.

Genome annotation databases

EnsemblBacteriaiCAJ11026; CAJ11026; BAB1_1070.
GeneIDi3787724.
KEGGibmf:BAB1_1070.
PATRICi17845082. VBIBruMel86222_1113.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040264 Genomic DNA. Translation: CAJ11026.1 .
RefSeqi YP_414473.1. NC_007618.1.

3D structure databases

ProteinModelPortali Q2YQ23.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 359391.BAB1_1070.

Proteomic databases

PRIDEi Q2YQ23.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ11026 ; CAJ11026 ; BAB1_1070 .
GeneIDi 3787724.
KEGGi bmf:BAB1_1070.
PATRICi 17845082. VBIBruMel86222_1113.

Phylogenomic databases

eggNOGi COG0655.
HOGENOMi HOG000030539.
KOi K03809.
OMAi YGHVESM.
OrthoDBi EOG6384K0.

Enzyme and pathway databases

BioCyci BABO359391:GKDV-1089-MONOMER.
BMEL359391:GJOQ-1089-MONOMER.

Family and domain databases

Gene3Di 3.40.50.360. 1 hit.
HAMAPi MF_01017. NQOR.
InterProi IPR008254. Flavodoxin/NO_synth.
IPR029039. Flavoprotein-like.
IPR010089. Flavoprotein_WrbA.
IPR005025. FMN_Rdtase-like.
[Graphical view ]
Pfami PF03358. FMN_red. 1 hit.
[Graphical view ]
SUPFAMi SSF52218. SSF52218. 1 hit.
TIGRFAMsi TIGR01755. flav_wrbA. 1 hit.
PROSITEi PS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiNQOR_BRUA2
AccessioniPrimary (citable) accession number: Q2YQ23
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: February 7, 2006
Last modified: June 11, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi