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Protein

NAD(P)H dehydrogenase (quinone)

Gene

BAB1_1070

Organism
Brucella abortus (strain 2308)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

NAD(P)H + a quinone = NAD(P)+ + a hydroquinone.UniRule annotation

Cofactori

FMNUniRule annotationNote: Binds 1 FMN per monomer.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei12 – 121NAD(P)UniRule annotation
Binding sitei98 – 981SubstrateUniRule annotation
Binding sitei134 – 1341FMNUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 145FMNUniRule annotation
Nucleotide bindingi110 – 16253FMNUniRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Flavoprotein, FMN, NAD, NADP, Nucleotide-binding

Enzyme and pathway databases

BioCyciBABO359391:GKDV-1089-MONOMER.
BMEL359391:GJOQ-1089-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
NAD(P)H dehydrogenase (quinone)UniRule annotation (EC:1.6.5.2UniRule annotation)
Alternative name(s):
Flavoprotein WrbA
NAD(P)H:quinone oxidoreductaseUniRule annotation
Short name:
NQOUniRule annotation
Gene namesi
Ordered Locus Names:BAB1_1070
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719 Componenti: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 199199NAD(P)H dehydrogenase (quinone)PRO_0000291007Add
BLAST

Proteomic databases

PRIDEiQ2YQ23.

Interactioni

Protein-protein interaction databases

STRINGi359391.BAB1_1070.

Structurei

3D structure databases

ProteinModelPortaliQ2YQ23.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 190187Flavodoxin-likeUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the WrbA family.UniRule annotation
Contains 1 flavodoxin-like domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG0655.
HOGENOMiHOG000030539.
KOiK03809.
OMAiQAFAHVP.
OrthoDBiEOG6384K0.

Family and domain databases

Gene3Di3.40.50.360. 1 hit.
HAMAPiMF_01017. NQOR.
InterProiIPR008254. Flavodoxin/NO_synth.
IPR029039. Flavoprotein-like.
IPR010089. Flavoprotein_WrbA.
IPR005025. FMN_Rdtase-like.
[Graphical view]
PfamiPF03358. FMN_red. 1 hit.
[Graphical view]
SUPFAMiSSF52218. SSF52218. 1 hit.
TIGRFAMsiTIGR01755. flav_wrbA. 1 hit.
PROSITEiPS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2YQ23-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKMLVLYYS AYGYMEQMAK AAAEGAREGG AEVTLKRVPE LVPEEVAKAS
60 70 80 90 100
HYKIDQEVPI ATPGELADYD AIIIGTATRY GMMASQMKNF LDQTGGLWAK
110 120 130 140 150
GALINKVGSV MVSTATQHGG AELALISTQW QMQHHGMIIV PLSYAYREQM
160 170 180 190
GNDVVRGGAP YGMTTTADGD GSRQPSAQEL DGARFQGRRV AEITAKLHG
Length:199
Mass (Da):21,442
Last modified:February 7, 2006 - v1
Checksum:i1E70DC2A51E5A676
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA. Translation: CAJ11026.1.
RefSeqiWP_002964168.1. NZ_KN046823.1.
YP_414473.1. NC_007618.1.

Genome annotation databases

EnsemblBacteriaiCAJ11026; CAJ11026; BAB1_1070.
GeneIDi3787724.
KEGGibmf:BAB1_1070.
PATRICi17845082. VBIBruMel86222_1113.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA. Translation: CAJ11026.1.
RefSeqiWP_002964168.1. NZ_KN046823.1.
YP_414473.1. NC_007618.1.

3D structure databases

ProteinModelPortaliQ2YQ23.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi359391.BAB1_1070.

Proteomic databases

PRIDEiQ2YQ23.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ11026; CAJ11026; BAB1_1070.
GeneIDi3787724.
KEGGibmf:BAB1_1070.
PATRICi17845082. VBIBruMel86222_1113.

Phylogenomic databases

eggNOGiCOG0655.
HOGENOMiHOG000030539.
KOiK03809.
OMAiQAFAHVP.
OrthoDBiEOG6384K0.

Enzyme and pathway databases

BioCyciBABO359391:GKDV-1089-MONOMER.
BMEL359391:GJOQ-1089-MONOMER.

Family and domain databases

Gene3Di3.40.50.360. 1 hit.
HAMAPiMF_01017. NQOR.
InterProiIPR008254. Flavodoxin/NO_synth.
IPR029039. Flavoprotein-like.
IPR010089. Flavoprotein_WrbA.
IPR005025. FMN_Rdtase-like.
[Graphical view]
PfamiPF03358. FMN_red. 1 hit.
[Graphical view]
SUPFAMiSSF52218. SSF52218. 1 hit.
TIGRFAMsiTIGR01755. flav_wrbA. 1 hit.
PROSITEiPS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiNQOR_BRUA2
AccessioniPrimary (citable) accession number: Q2YQ23
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: February 7, 2006
Last modified: May 27, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.