Q2YQ23 (WRBA_BRUA2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Flavoprotein WrbA

Gene names

Name:	wrbA
Ordered Locus Names:	BAB1_1070

Organism

Brucella abortus (strain 2308) [Complete proteome] [HAMAP]

Taxonomic identifier

359391 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella abortus

Protein attributes

Sequence length	199 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Binds 1 FMN per monomer By similarity.
Sequence similarities	Belongs to the WrbA family. Contains 1 flavodoxin-like domain.

Ontologies

Keywords
Ligand	FMN Flavoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	negative regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro oxidation-reduction process Inferred from electronic annotation. Source: GOC
Molecular_function	FMN binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 199	199	Flavoprotein WrbA HAMAP-Rule MF_01017		PRO_0000291007
Regions
	Domain	4 – 190	187	Flavodoxin-like
	Nucleotide binding	10 – 14	5	FMN By similarity
	Nucleotide binding	110 – 162	53	FMN By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2YQ23 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 1E70DC2A51E5A676	FASTA	199	21,442
	10 20 30 40 50 60 MVKMLVLYYS AYGYMEQMAK AAAEGAREGG AEVTLKRVPE LVPEEVAKAS HYKIDQEVPI 70 80 90 100 110 120 ATPGELADYD AIIIGTATRY GMMASQMKNF LDQTGGLWAK GALINKVGSV MVSTATQHGG 130 140 150 160 170 180 AELALISTQW QMQHHGMIIV PLSYAYREQM GNDVVRGGAP YGMTTTADGD GSRQPSAQEL 190 DGARFQGRRV AEITAKLHG

References

[1]

"Whole-genome analyses of speciation events in pathogenic Brucellae." Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E. Infect. Immun. 73:8353-8361(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 2308.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM040264 Genomic DNA. Translation: CAJ11026.1.
RefSeq	YP_414473.1. NC_007618.1.
3D structure databases
ProteinModelPortal	Q2YQ23.
ModBase	Search...
Protein-protein interaction databases
STRING	359391.BAB1_1070.
Proteomic databases
PRIDE	Q2YQ23.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAJ11026; CAJ11026; BAB1_1070.
GeneID	3787724.
KEGG	bmf:BAB1_1070.
PATRIC	17845082. VBIBruMel86222_1113.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0655.
HOGENOM	HOG000030539.
KO	K03809.
OMA	DVAKASH.
ProtClustDB	PRK03767.
Enzyme and pathway databases
BioCyc	BMEL359391:GJOQ-1089-MONOMER.
Family and domain databases
HAMAP	MF_01017. Flav_WrbA.
InterPro	IPR008254. Flavodoxin/NO_synth. IPR010089. Flavoprotein_WrbA. IPR005025. FMN_red. [Graphical view]
Pfam	PF03358. FMN_red. 1 hit. [Graphical view]
TIGRFAMs	TIGR01755. flav_wrbA. 1 hit.
PROSITE	PS50902. FLAVODOXIN_LIKE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

WRBA_BRUA2

Accession

Primary (citable) accession number: Q2YQ23

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 12, 2007
Last sequence update:	February 7, 2006
Last modified:	May 1, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program