Q2YPX7 (SSB_BRUA2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Single-stranded DNA-binding protein
Short name=SSB

Alternative name(s):
Helix-destabilizing protein

Gene names

Name:	ssb
Ordered Locus Names:	BAB1_1126

Organism

Brucella abortus (strain 2308) [Complete proteome] [HAMAP]

Taxonomic identifier

359391 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella abortus

Protein attributes

Sequence length	168 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair By similarity.
Sequence similarities	Contains 1 SSB domain.

Ontologies

Keywords
Biological process	DNA damage DNA repair DNA replication
Ligand	DNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA repair Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	single-stranded DNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 168	168	Single-stranded DNA-binding protein		PRO_0000096014
Regions
	Domain	5 – 111	107	SSB
	DNA binding	54 – 60	7	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2YPX7 [UniParc]. Last modified December 20, 2005. Version 1. Checksum: ECDDE21EDDDD7886	FASTA	168	18,398
	10 20 30 40 50 60 MAGSVNKVIL VGNLGADPEI RRLNSGDMVA NLRIATSESW RDRQTGERKD RTEWHSVVIF 70 80 90 100 110 120 NENLAKVAEQ YLKKGAKVYI EGALQTRKWQ DQNGNDRYSK EIVLQKFRGE LQMLDSRSEG 130 140 150 160 GEGRSFGGGG NRNQMSDYSG GGGDFGSSGP SSGSSGGFSR DLDDEIPF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Isolation of Brucella abortus ssb and uvrA genes from a genomic library by use of lymphocytes as probes." Zhu Y., Oliveira S.C., Splitter G.A. Infect. Immun. 61:5339-5344(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Whole-genome analyses of speciation events in pathogenic Brucellae." Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E. Infect. Immun. 73:8353-8361(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 2308.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L10843 Unassigned DNA. Translation: AAA16818.1. AM040264 Genomic DNA. Translation: CAJ11082.1.
PIR	I40352.
RefSeq	YP_414519.1. NC_007618.1.
3D structure databases
ProteinModelPortal	Q2YPX7.
SMR	Q2YPX7. Positions 5-121.
ModBase	Search...
Protein-protein interaction databases
STRING	359391.BAB1_1126.
Proteomic databases
PRIDE	Q2YPX7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAJ11082; CAJ11082; BAB1_1126.
GeneID	3787774.
KEGG	bmf:BAB1_1126.
PATRIC	17845210. VBIBruMel86222_1175.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0629.
HOGENOM	HOG000106483.
KO	K03111.
OMA	IATSENW.
ProtClustDB	CLSK898240.
Enzyme and pathway databases
BioCyc	BMEL359391:GJOQ-1148-MONOMER.
Family and domain databases
Gene3D	2.40.50.140. 1 hit.
InterPro	IPR012340. NA-bd_OB-fold. IPR000424. Primosome_PriB/ssb. IPR011344. ssDNA-bd. [Graphical view]
PANTHER	PTHR10302. PTHR10302. 1 hit.
Pfam	PF00436. SSB. 1 hit. [Graphical view]
PIRSF	PIRSF002070. SSB. 1 hit.
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMs	TIGR00621. ssb. 1 hit.
PROSITE	PS50935. SSB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SSB_BRUA2

Accession

Primary (citable) accession number: Q2YPX7
Secondary accession number(s): Q07432, Q57D35

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 7, 2006
Last sequence update:	December 20, 2005
Last modified:	May 1, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program