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Protein

Single-stranded DNA-binding protein

Gene

ssb

Organism
Brucella abortus (strain 2308)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi54 – 607UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA recombination, DNA repair, DNA replication

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciBABO359391:GKDV-1148-MONOMER.
BMEL359391:GJOQ-1148-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Single-stranded DNA-binding proteinUniRule annotation
Short name:
SSBUniRule annotation
Gene namesi
Name:ssb
Ordered Locus Names:BAB1_1126
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719 Componenti: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 168168Single-stranded DNA-binding proteinPRO_0000096014Add
BLAST

Proteomic databases

PRIDEiQ2YPX7.

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi359391.BAB1_1126.

Structurei

3D structure databases

ProteinModelPortaliQ2YPX7.
SMRiQ2YPX7. Positions 5-121.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 111107SSBUniRule annotationAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi163 – 1686Important for interaction with partner proteinsUniRule annotation

Sequence similaritiesi

Contains 1 SSB domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG0629.
HOGENOMiHOG000106483.
KOiK03111.
OMAiTDRYSTE.
OrthoDBiEOG6M9F32.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00984. SSB.
InterProiIPR012340. NA-bd_OB-fold.
IPR000424. Primosome_PriB/ssb.
IPR011344. ssDNA-bd.
[Graphical view]
PANTHERiPTHR10302. PTHR10302. 1 hit.
PfamiPF00436. SSB. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00621. ssb. 1 hit.
PROSITEiPS50935. SSB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2YPX7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGSVNKVIL VGNLGADPEI RRLNSGDMVA NLRIATSESW RDRQTGERKD
60 70 80 90 100
RTEWHSVVIF NENLAKVAEQ YLKKGAKVYI EGALQTRKWQ DQNGNDRYSK
110 120 130 140 150
EIVLQKFRGE LQMLDSRSEG GEGRSFGGGG NRNQMSDYSG GGGDFGSSGP
160
SSGSSGGFSR DLDDEIPF
Length:168
Mass (Da):18,398
Last modified:December 20, 2005 - v1
Checksum:iECDDE21EDDDD7886
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10843 Unassigned DNA. Translation: AAA16818.1.
AM040264 Genomic DNA. Translation: CAJ11082.1.
PIRiI40352.
RefSeqiWP_002964231.1. NZ_KN046823.1.
YP_414519.1. NC_007618.1.

Genome annotation databases

EnsemblBacteriaiCAJ11082; CAJ11082; BAB1_1126.
GeneIDi3787774.
KEGGibmf:BAB1_1126.
PATRICi17845210. VBIBruMel86222_1175.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10843 Unassigned DNA. Translation: AAA16818.1.
AM040264 Genomic DNA. Translation: CAJ11082.1.
PIRiI40352.
RefSeqiWP_002964231.1. NZ_KN046823.1.
YP_414519.1. NC_007618.1.

3D structure databases

ProteinModelPortaliQ2YPX7.
SMRiQ2YPX7. Positions 5-121.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi359391.BAB1_1126.

Proteomic databases

PRIDEiQ2YPX7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ11082; CAJ11082; BAB1_1126.
GeneIDi3787774.
KEGGibmf:BAB1_1126.
PATRICi17845210. VBIBruMel86222_1175.

Phylogenomic databases

eggNOGiCOG0629.
HOGENOMiHOG000106483.
KOiK03111.
OMAiTDRYSTE.
OrthoDBiEOG6M9F32.

Enzyme and pathway databases

BioCyciBABO359391:GKDV-1148-MONOMER.
BMEL359391:GJOQ-1148-MONOMER.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00984. SSB.
InterProiIPR012340. NA-bd_OB-fold.
IPR000424. Primosome_PriB/ssb.
IPR011344. ssDNA-bd.
[Graphical view]
PANTHERiPTHR10302. PTHR10302. 1 hit.
PfamiPF00436. SSB. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00621. ssb. 1 hit.
PROSITEiPS50935. SSB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Isolation of Brucella abortus ssb and uvrA genes from a genomic library by use of lymphocytes as probes."
    Zhu Y., Oliveira S.C., Splitter G.A.
    Infect. Immun. 61:5339-5344(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiSSB_BRUA2
AccessioniPrimary (citable) accession number: Q2YPX7
Secondary accession number(s): Q07432, Q57D35
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 7, 2006
Last sequence update: December 20, 2005
Last modified: May 27, 2015
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.