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Q2YPN5

- KCY_BRUA2

UniProt

Q2YPN5 - KCY_BRUA2

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Protein

Cytidylate kinase

Gene
cmk, BAB1_0024
Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (d)CMP = ADP + (d)CDP.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 239ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. cytidylate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pyrimidine nucleotide metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBABO359391:GKDV-25-MONOMER.
BMEL359391:GJOQ-25-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytidylate kinase (EC:2.7.4.25)
Short name:
CK
Alternative name(s):
Cytidine monophosphate kinase
Short name:
CMP kinase
Gene namesi
Name:cmk
Ordered Locus Names:BAB1_0024
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719: Chromosome I

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 219219Cytidylate kinaseUniRule annotationPRO_1000048190Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi359391.BAB1_0024.

Structurei

3D structure databases

ProteinModelPortaliQ2YPN5.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0283.
HOGENOMiHOG000242849.
KOiK00945.
OMAiHDVELEN.
OrthoDBiEOG6WDSMP.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00238. Cytidyl_kinase_type1.
InterProiIPR003136. Cytidylate_kin.
IPR011994. Cytidylate_kinase_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR21299:SF2. PTHR21299:SF2. 1 hit.
PfamiPF02224. Cytidylate_kin. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00017. cmk. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2YPN5-1 [UniParc]FASTAAdd to Basket

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MKSFVVAPFI VAIDGPAASG KGTLARRIAT HYGMPHLDTG LTYRAVAKAL    50
LDKGLPLDDE ALATDAALSL DLLAMDKAVL SAHAIGEAAS KVAVMPAVRR 100
ALVEAQRHFA NALPSSVLDG RDIGTVVCPD AAIKLFVTAS PEVRARRRFD 150
EVLARGDTAD FAEILADLKK RDERDMNRTD SPLRPAEDAH LLDASEMSIE 200
AAFLAAKKLI DHALAQHRG 219
Length:219
Mass (Da):23,382
Last modified:February 7, 2006 - v1
Checksum:iAF7E4369C620178B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040264 Genomic DNA. Translation: CAJ09980.1.
RefSeqiYP_413527.1. NC_007618.1.

Genome annotation databases

EnsemblBacteriaiCAJ09980; CAJ09980; BAB1_0024.
GeneIDi3786842.
KEGGibmf:BAB1_0024.
PATRICi17842865. VBIBruMel86222_0025.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040264 Genomic DNA. Translation: CAJ09980.1 .
RefSeqi YP_413527.1. NC_007618.1.

3D structure databases

ProteinModelPortali Q2YPN5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 359391.BAB1_0024.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ09980 ; CAJ09980 ; BAB1_0024 .
GeneIDi 3786842.
KEGGi bmf:BAB1_0024.
PATRICi 17842865. VBIBruMel86222_0025.

Phylogenomic databases

eggNOGi COG0283.
HOGENOMi HOG000242849.
KOi K00945.
OMAi HDVELEN.
OrthoDBi EOG6WDSMP.

Enzyme and pathway databases

BioCyci BABO359391:GKDV-25-MONOMER.
BMEL359391:GJOQ-25-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00238. Cytidyl_kinase_type1.
InterProi IPR003136. Cytidylate_kin.
IPR011994. Cytidylate_kinase_dom.
IPR027417. P-loop_NTPase.
[Graphical view ]
PANTHERi PTHR21299:SF2. PTHR21299:SF2. 1 hit.
Pfami PF02224. Cytidylate_kin. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00017. cmk. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiKCY_BRUA2
AccessioniPrimary (citable) accession number: Q2YPN5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 7, 2006
Last modified: May 14, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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