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Reviewed, UniProtKB/Swiss-Prot Q2YPN5 (KCY_BRUA2)

Last modified February 9, 2010. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Cytidylate kinase
      Short name=CK
    EC=2.7.4.14
Alternative name(s):
    Cytidine monophosphate kinase
      Short name=CMP kinase
Gene names
Name: cmk
Ordered Locus Names: BAB1_0024
OrganismBrucella abortus (strain 2308) [Complete proteome] [HAMAP]
Taxonomic identifier359391 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length219 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238

Subcellular location

Cytoplasm By similarity HAMAP MF_00238.

Sequence similarities

Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processpyrimidine nucleotide metabolic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: HAMAP

cytidylate kinase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 219219Cytidylate kinase HAMAP MF_00238
PRO_1000048190

Regions

Nucleotide binding15 – 239ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2YPN5-1 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: AF7E4369C620178B

FASTA21923,382
        10         20         30         40         50         60 
MKSFVVAPFI VAIDGPAASG KGTLARRIAT HYGMPHLDTG LTYRAVAKAL LDKGLPLDDE 

        70         80         90        100        110        120 
ALATDAALSL DLLAMDKAVL SAHAIGEAAS KVAVMPAVRR ALVEAQRHFA NALPSSVLDG 

       130        140        150        160        170        180 
RDIGTVVCPD AAIKLFVTAS PEVRARRRFD EVLARGDTAD FAEILADLKK RDERDMNRTD 

       190        200        210 
SPLRPAEDAH LLDASEMSIE AAFLAAKKLI DHALAQHRG 

« Hide

References

[1]"Whole-genome analyses of speciation events in pathogenic Brucellae."
Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.
Infect. Immun. 73:8353-8361(2005) [PubMed: 16299333] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM040264 Genomic DNA. Translation: CAJ09980.1.
RefSeqYP_413527.1.

3D structure databases

SMRQ2YPN5. Positions 8-211.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2YPN5.

Genome annotation databases

GeneID3786842.
GenomeReviewsGene locus BAB1_0024 in contig AM040264_GR.
KEGGbmf:BAB1_0024.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0283.
HOGENOMHBG354377.
OMADTGLLYR.

Enzyme and pathway databases

BioCycBMEL359391:BAB1_0024-MONOMER.

Family and domain databases

HAMAPMF_00238. Cytidyl_kinase_type1.
[Tree]
InterProIPR000850. Adenylate_kin.
IPR003136. Cytidylate_kin.
IPR011994. Cytidylate_kinase_dom.
[Graphical view]
PANTHERPTHR21299:SF2. Cytidylate_kin. 1 hit.
PfamPF00406. ADK. 1 hit.
PF02224. Cytidylate_kin. 1 hit.
[Graphical view]
TIGRFAMsTIGR00017. cmk. 1 hit.
ProtoNetSearch...

Entry information

Entry nameKCY_BRUA2
AccessionPrimary (citable) accession number: Q2YPN5
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 7, 2006
Last modified: February 9, 2010
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Brucella abortus strain 2308

Brucella abortus (strain 2308): entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents