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Q2YPN5

- KCY_BRUA2

UniProt

Q2YPN5 - KCY_BRUA2

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Protein

Cytidylate kinase

Gene

cmk

Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (d)CMP = ADP + (d)CDP.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 239ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. cytidylate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pyrimidine nucleotide metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBABO359391:GKDV-25-MONOMER.
BMEL359391:GJOQ-25-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytidylate kinaseUniRule annotation (EC:2.7.4.25UniRule annotation)
Short name:
CKUniRule annotation
Alternative name(s):
Cytidine monophosphate kinaseUniRule annotation
Short name:
CMP kinaseUniRule annotation
Gene namesi
Name:cmkUniRule annotation
Ordered Locus Names:BAB1_0024
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719: Chromosome I

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 219219Cytidylate kinasePRO_1000048190Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi359391.BAB1_0024.

Structurei

3D structure databases

ProteinModelPortaliQ2YPN5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytidylate kinase family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0283.
HOGENOMiHOG000242849.
KOiK00945.
OMAiHDVELEN.
OrthoDBiEOG6WDSMP.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00238. Cytidyl_kinase_type1.
InterProiIPR003136. Cytidylate_kin.
IPR011994. Cytidylate_kinase_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR21299:SF2. PTHR21299:SF2. 1 hit.
PfamiPF02224. Cytidylate_kin. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00017. cmk. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2YPN5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKSFVVAPFI VAIDGPAASG KGTLARRIAT HYGMPHLDTG LTYRAVAKAL
60 70 80 90 100
LDKGLPLDDE ALATDAALSL DLLAMDKAVL SAHAIGEAAS KVAVMPAVRR
110 120 130 140 150
ALVEAQRHFA NALPSSVLDG RDIGTVVCPD AAIKLFVTAS PEVRARRRFD
160 170 180 190 200
EVLARGDTAD FAEILADLKK RDERDMNRTD SPLRPAEDAH LLDASEMSIE
210
AAFLAAKKLI DHALAQHRG
Length:219
Mass (Da):23,382
Last modified:February 7, 2006 - v1
Checksum:iAF7E4369C620178B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040264 Genomic DNA. Translation: CAJ09980.1.
RefSeqiYP_413527.1. NC_007618.1.

Genome annotation databases

EnsemblBacteriaiCAJ09980; CAJ09980; BAB1_0024.
GeneIDi3786842.
KEGGibmf:BAB1_0024.
PATRICi17842865. VBIBruMel86222_0025.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040264 Genomic DNA. Translation: CAJ09980.1 .
RefSeqi YP_413527.1. NC_007618.1.

3D structure databases

ProteinModelPortali Q2YPN5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 359391.BAB1_0024.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ09980 ; CAJ09980 ; BAB1_0024 .
GeneIDi 3786842.
KEGGi bmf:BAB1_0024.
PATRICi 17842865. VBIBruMel86222_0025.

Phylogenomic databases

eggNOGi COG0283.
HOGENOMi HOG000242849.
KOi K00945.
OMAi HDVELEN.
OrthoDBi EOG6WDSMP.

Enzyme and pathway databases

BioCyci BABO359391:GKDV-25-MONOMER.
BMEL359391:GJOQ-25-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00238. Cytidyl_kinase_type1.
InterProi IPR003136. Cytidylate_kin.
IPR011994. Cytidylate_kinase_dom.
IPR027417. P-loop_NTPase.
[Graphical view ]
PANTHERi PTHR21299:SF2. PTHR21299:SF2. 1 hit.
Pfami PF02224. Cytidylate_kin. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00017. cmk. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiKCY_BRUA2
AccessioniPrimary (citable) accession number: Q2YPN5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 7, 2006
Last modified: October 29, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3