Reviewed, UniProtKB/Swiss-Prot Q2YPM3 (RECF_BRUA2)

Names and origin

Protein names

Recommended name:
    DNA replication and repair protein recF

Gene names

Name:	recF
Ordered Locus Names:	BAB1_0003

Organism

Brucella abortus (strain 2308) [Complete proteome] [HAMAP]

Taxonomic identifier

359391 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	384 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	The recF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the recF family.

Ontologies

Keywords
Biological process	DNA damage DNA repair DNA replication SOS response
Cellular component	Cytoplasm
Ligand	ATP-binding DNA-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: HAMAP SOS response Inferred from electronic annotation. Source: HAMAP
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro single-stranded DNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 384	384	DNA replication and repair protein recF HAMAP MF_00365		PRO_0000236113
Regions
	Nucleotide binding	43 – 50	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q2YPM3-1 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 418A748CCCE460CC	FASTA	384	41,494
	10 20 30 40 50 60 MEAKDHIERR PDRVSIRRLK LVNFRNYAEL SLPLGPGHVV LTGENGSGKT NLIEAISFLS 70 80 90 100 110 120 PGRGLRRAAY DDVARANAEG GFAIHAALDC MIYGDAEIGT GTAGGGEGGR KVRINRIAAS 130 140 150 160 170 180 ADDLLDYARI LWVVPSMDGL FTGGASDRRR FLDRMVLAID TAHGKRVLDY EKAMRSRNRL 190 200 210 220 230 240 LNDGSNDDQW LDAIENQMAE LGTAIAAARA QAMRLIAAMI ERLPAEGPFP KADCFLEGAL 250 260 270 280 290 300 ESRIGVEAAL DLEEDFRRTL RDGRARDRAA GRTLDGPHRT DLIVQHRPKS MPAALCSTGE 310 320 330 340 350 360 QKALLIGLIL AHARLTAELS GMAPILLLDE IAAHLDMGRR AALFGILDEL GGQAFMTGTD 370 380 RALFDALAGD AQFFNVSAGQ LTGI

References

[1]

"Whole-genome analyses of speciation events in pathogenic Brucellae." Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E. Infect. Immun. 73:8353-8361(2005) [PubMed: 16299333] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM040264 Genomic DNA. Translation: CAJ09959.1.
RefSeq	YP_413509.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q2YPM3.
Genome annotation databases
GeneID	3786823.
GenomeReviews	Gene locus BAB1_0003 in contig AM040264_GR.
KEGG	bmf:BAB1_0003.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG645124.
OMA	NAQGKSN.
Enzyme and pathway databases
BioCyc	BMEL359391:BAB1_0003-MON.
Family and domain databases
HAMAP	MF_00365. [Tree]
InterPro	IPR003593. ATPase_AAA+_core. IPR001238. DNA-binding_RecF. IPR018078. DNA-binding_RecF_CS. IPR003395. RecF/RecN/SMC_N. [Graphical view]
Pfam	PF02463. SMC_N. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
PROSITE	PS00617. RECF_1. 1 hit. PS00618. RECF_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RECF_BRUA2

Accession

Primary (citable) accession number: Q2YPM3

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 16, 2006
Last sequence update:	February 7, 2006
Last modified:	December 15, 2009
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)