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Q2YPC3 (YACG_BRUA2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
DNA gyrase inhibitor YacG
Gene names
Name:yacG
Ordered Locus Names:BAB1_0280
OrganismBrucella abortus (strain 2308) [Complete proteome] [HAMAP]
Taxonomic identifier359391 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length57 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase By similarity. HAMAP-Rule MF_00649

Cofactor

Binds 1 zinc ion By similarity. HAMAP-Rule MF_00649

Subunit structure

Interacts with GyrB By similarity. HAMAP-Rule MF_00649

Sequence similarities

Belongs to the DNA gyrase inhibitor YacG family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 5757DNA gyrase inhibitor YacG HAMAP-Rule MF_00649
PRO_1000056968

Sites

Metal binding101Zinc By similarity
Metal binding131Zinc By similarity
Metal binding251Zinc By similarity
Metal binding291Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2YPC3 [UniParc].

Last modified December 20, 2005. Version 1.
Checksum: AE0B63B8A995213D

FASTA576,354
        10         20         30         40         50 
MAPLRPTRPC PECGKPSTRE AYPFCSPRCK NIDLNRWLSG SYVIAGKPLG EEDENDS 

« Hide

References

[1]"Whole-genome analyses of speciation events in pathogenic Brucellae."
Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.
Infect. Immun. 73:8353-8361(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 2308.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM040264 Genomic DNA. Translation: CAJ10236.1.
RefSeqYP_413754.1. NC_007618.1.

3D structure databases

ProteinModelPortalQ2YPC3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING359391.BAB1_0280.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ10236; CAJ10236; BAB1_0280.
GeneID3787065.
KEGGbmf:BAB1_0280.
PATRIC17843409. VBIBruMel86222_0292.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3024.
HOGENOMHOG000255917.
KOK09862.
OMAEAWRRES.
OrthoDBEOG65F8ZX.

Enzyme and pathway databases

BioCycBABO359391:GKDV-285-MONOMER.
BMEL359391:GJOQ-285-MONOMER.

Family and domain databases

Gene3D3.30.50.10. 1 hit.
HAMAPMF_00649. DNA_gyrase_inhibitor_YacG.
InterProIPR005584. DNA_gyrase_inhibitor_YacG.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamPF03884. DUF329. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYACG_BRUA2
AccessionPrimary (citable) accession number: Q2YPC3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 20, 2005
Last modified: May 14, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella abortus strain 2308

Brucella abortus (strain 2308): entries and gene names