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Reviewed, UniProtKB/Swiss-Prot Q2YP58 (THIG_BRUA2)

Last modified December 15, 2009. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Thiazole biosynthesis protein thiG
Gene names
Name: thiG
Ordered Locus Names: BAB1_0216
OrganismBrucella abortus (strain 2308) [Complete proteome] [HAMAP]
Taxonomic identifier359391 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length256 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Required for the synthesis of the thiazole moiety of thiamine By similarity.

Cofactor

FMN Potential.

Pathway

Cofactor biosynthesis; thiamine diphosphate biosynthesis. HAMAP MF_00443

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the thiG family.

Ontologies

Keywords
   Biological processThiamine biosynthesis
   Cellular componentCytoplasm
   LigandFMN
Flavoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processthiamin biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioncatalytic activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 256256Thiazole biosynthesis protein thiG HAMAP MF_00443
PRO_0000236333

Sequences

Sequence LengthMass (Da)Tools
Q2YP58-1 [UniParc].

Last modified December 20, 2005. Version 1.
Checksum: B4BB05AAAF6E0510

FASTA25627,321
        10         20         30         40         50         60 
MLEFYGKRFE SRLLLGTAQY PSPSILADAV RASLSRIVTV SLRRESGEAR AGQDFWALIK 

        70         80         90        100        110        120 
ALGVAVLPNT AGCHTPREAI TTAHMAREVF GTNWIKLEVI GDTDTLQPDP FGLVEAARIL 

       130        140        150        160        170        180 
CDEGFEVFPY MNDDLIVAER LIEAGCKVLM PWGAPIGSGR GLNNPYALKT MRAHFPDIPL 

       190        200        210        220        230        240 
VVDAGIGVPS HAAAAMELGF DAVLINTAVA KAGDPAAMAR AFALAVEAGR LAYEADPIEA 

       250 
RDMASPSTPL LGKAFL 

« Hide

References

[1]"Whole-genome analyses of speciation events in pathogenic Brucellae."
Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.
Infect. Immun. 73:8353-8361(2005) [PubMed: 16299333] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

AM040264 Genomic DNA. Translation: CAJ10172.1.
RefSeqYP_413698.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ2YP58.

Genome annotation databases

GeneID3787004.
GenomeReviewsGene locus BAB1_0216 in contig AM040264_GR.
KEGGbmf:BAB1_0216.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG296821.
OMAVAIRRTN.

Enzyme and pathway databases

BioCycBMEL359391:BAB1_0216-MON.

Family and domain databases

HAMAPMF_00443.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR008867. ThiG.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PfamPF05690. ThiG. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTHIG_BRUA2
AccessionPrimary (citable) accession number: Q2YP58
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: December 20, 2005
Last modified: December 15, 2009
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Brucella abortus strain 2308

Brucella abortus (strain 2308): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents