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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Brucella abortus (strain 2308)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:BAB1_0896
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000002719 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002419951 – 585Arginine--tRNA ligaseAdd BLAST585

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ2YNJ9.
SMRiQ2YNJ9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi131 – 141"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000247214.
KOiK01887.
OMAiNKPLHLG.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2YNJ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIFADFDAR IKKTFQDIDL KPKDGGELDL SRIGVEPPRD ASHGDIATNA
60 70 80 90 100
AMVLSKAVGQ NPRELAARIA EALKADEDVE SVDVAGPGFI NLRLKASYWQ
110 120 130 140 150
RELLVMLNEG TDFGRSRLGA GKKVNVEYVS ANPTGPMHVG HCRGAVVGDV
160 170 180 190 200
LANLLKFAGY DVVKEYYIND AGAQIDVLAR SVMLRYREAL GESIGEIPAG
210 220 230 240 250
LYPGDYLVRV GQELAGEFGT KLLEMPEAEA LAIVKDRTID AMMAMIRADL
260 270 280 290 300
DALNVHHDVF YSERKLHVDH ARAIRNAIND LTLKGHVYKG KLPPPKGRLP
310 320 330 340 350
EDWEDREQTL FRSTEVGDDI DRPLMKSDGS FTYFAGDVTY FKDKYDRGFN
360 370 380 390 400
EMIYVLGADH GGYVKRLEAV ARAVSDGKAK LTVLLCQLVK LFRNGEPVRM
410 420 430 440 450
SKRAGEFITL RDVVDEVGRD PVRFMMLYRK NDAPLDFDFA KVTEQSKDNP
460 470 480 490 500
VFYVQYASAR CHSVFRQAAD QLGLVDLDRV AMGSHFEKLT DESEIALVRK
510 520 530 540 550
LAEYPRLIES AAIHQEPHRL AFYLYDLASS FHSQWNRGAE NPDLRFIKVN
560 570 580
DPDLSLARLG LVQVVSDVLT SGLTIIGADA PTEMR
Length:585
Mass (Da):65,186
Last modified:February 7, 2006 - v1
Checksum:i354143BD9F45FD56
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA. Translation: CAJ10852.1.
RefSeqiWP_002964007.1. NZ_KN046823.1.

Genome annotation databases

EnsemblBacteriaiCAJ10852; CAJ10852; BAB1_0896.
KEGGibmf:BAB1_0896.
PATRICifig|359391.11.peg.3204.

Similar proteinsi

Entry informationi

Entry nameiSYR_BRUA2
AccessioniPrimary (citable) accession number: Q2YNJ9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: February 7, 2006
Last modified: August 30, 2017
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families