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Q2YNH6

- LOLD_BRUA2

UniProt

Q2YNH6 - LOLD_BRUA2

Protein

Lipoprotein-releasing system ATP-binding protein LolD

Gene

lolD

Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (07 Feb 2006)
      Previous versions | rss
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    Functioni

    Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi43 – 508ATPUniRule annotation

    GO - Molecular functioni

    1. ATPase activity Source: InterPro
    2. ATP binding Source: UniProtKB-HAMAP
    3. lipoprotein transporter activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Transport

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBABO359391:GKDV-858-MONOMER.
    BMEL359391:GJOQ-858-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Lipoprotein-releasing system ATP-binding protein LolDUniRule annotation (EC:3.6.3.-UniRule annotation)
    Gene namesi
    Name:lolDUniRule annotation
    Ordered Locus Names:BAB1_0844
    OrganismiBrucella abortus (strain 2308)
    Taxonomic identifieri359391 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000002719: Chromosome I

    Subcellular locationi

    Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

    GO - Cellular componenti

    1. ATP-binding cassette (ABC) transporter complex Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 227227Lipoprotein-releasing system ATP-binding protein LolDPRO_0000260195Add
    BLAST

    Interactioni

    Subunit structurei

    The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).UniRule annotation

    Protein-protein interaction databases

    STRINGi359391.BAB1_0844.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2YNH6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini7 – 227221ABC transporterUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. [View classification]UniRule annotation
    Contains 1 ABC transporter domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1136.
    KOiK09810.
    OMAiYNRGRPG.
    OrthoDBiEOG6T7N3V.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR003593. AAA+_ATPase.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR015854. ABC_transpr_LolD.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00005. ABC_tran. 1 hit.
    [Graphical view]
    SMARTiSM00382. AAA. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 1 hit.
    PS51244. LOLD. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2YNH6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAAEIILRLE RIGRAYKEAD RELIILNDAD FTLRRGEMVA LVAPSGAGKS    50
    TLLHTAGLLE RPDSGDVVLD GRSCSKLSDD ERTAVRRNDV GFVYQFHHLL 100
    PEFSALENVM LPQMIRGLSR KAAAERAQQL LEYMKIGKRA SHRPAELSGG 150
    EQQRVAIARA VANAPLVLLA DEPTGNLDPT TSSYVFGALE ALVRQSGLAA 200
    LIATHNHELA RRMDRRVTLK DGRVVDL 227
    Length:227
    Mass (Da):24,930
    Last modified:February 7, 2006 - v1
    Checksum:iE49DCFD20A3462C3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM040264 Genomic DNA. Translation: CAJ10800.1.
    RefSeqiYP_414275.1. NC_007618.1.

    Genome annotation databases

    EnsemblBacteriaiCAJ10800; CAJ10800; BAB1_0844.
    GeneIDi3788778.
    KEGGibmf:BAB1_0844.
    PATRICi17844601. VBIBruMel86222_0879.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM040264 Genomic DNA. Translation: CAJ10800.1 .
    RefSeqi YP_414275.1. NC_007618.1.

    3D structure databases

    ProteinModelPortali Q2YNH6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 359391.BAB1_0844.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAJ10800 ; CAJ10800 ; BAB1_0844 .
    GeneIDi 3788778.
    KEGGi bmf:BAB1_0844.
    PATRICi 17844601. VBIBruMel86222_0879.

    Phylogenomic databases

    eggNOGi COG1136.
    KOi K09810.
    OMAi YNRGRPG.
    OrthoDBi EOG6T7N3V.

    Enzyme and pathway databases

    BioCyci BABO359391:GKDV-858-MONOMER.
    BMEL359391:GJOQ-858-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR003593. AAA+_ATPase.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR015854. ABC_transpr_LolD.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00005. ABC_tran. 1 hit.
    [Graphical view ]
    SMARTi SM00382. AAA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 1 hit.
    PS51244. LOLD. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 2308.

    Entry informationi

    Entry nameiLOLD_BRUA2
    AccessioniPrimary (citable) accession number: Q2YNH6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 28, 2006
    Last sequence update: February 7, 2006
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Brucella abortus strain 2308
      Brucella abortus (strain 2308): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3