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Q2YNH6

- LOLD_BRUA2

UniProt

Q2YNH6 - LOLD_BRUA2

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Protein

Lipoprotein-releasing system ATP-binding protein LolD

Gene

lolD

Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi43 – 508ATPUniRule annotation

GO - Molecular functioni

  1. ATPase activity Source: InterPro
  2. ATP binding Source: UniProtKB-HAMAP
  3. lipoprotein transporter activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBABO359391:GKDV-858-MONOMER.
BMEL359391:GJOQ-858-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipoprotein-releasing system ATP-binding protein LolDUniRule annotation (EC:3.6.3.-UniRule annotation)
Gene namesi
Name:lolDUniRule annotation
Ordered Locus Names:BAB1_0844
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719: Chromosome I

Subcellular locationi

Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

  1. ATP-binding cassette (ABC) transporter complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 227227Lipoprotein-releasing system ATP-binding protein LolDPRO_0000260195Add
BLAST

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).UniRule annotation

Protein-protein interaction databases

STRINGi359391.BAB1_0844.

Structurei

3D structure databases

ProteinModelPortaliQ2YNH6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini7 – 227221ABC transporterUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. [View classification]UniRule annotation
Contains 1 ABC transporter domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG1136.
KOiK09810.
OMAiYNRGRPG.
OrthoDBiEOG6T7N3V.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR015854. ABC_transpr_LolD.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51244. LOLD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2YNH6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAAEIILRLE RIGRAYKEAD RELIILNDAD FTLRRGEMVA LVAPSGAGKS
60 70 80 90 100
TLLHTAGLLE RPDSGDVVLD GRSCSKLSDD ERTAVRRNDV GFVYQFHHLL
110 120 130 140 150
PEFSALENVM LPQMIRGLSR KAAAERAQQL LEYMKIGKRA SHRPAELSGG
160 170 180 190 200
EQQRVAIARA VANAPLVLLA DEPTGNLDPT TSSYVFGALE ALVRQSGLAA
210 220
LIATHNHELA RRMDRRVTLK DGRVVDL
Length:227
Mass (Da):24,930
Last modified:February 7, 2006 - v1
Checksum:iE49DCFD20A3462C3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040264 Genomic DNA. Translation: CAJ10800.1.
RefSeqiYP_414275.1. NC_007618.1.

Genome annotation databases

EnsemblBacteriaiCAJ10800; CAJ10800; BAB1_0844.
GeneIDi3788778.
KEGGibmf:BAB1_0844.
PATRICi17844601. VBIBruMel86222_0879.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040264 Genomic DNA. Translation: CAJ10800.1 .
RefSeqi YP_414275.1. NC_007618.1.

3D structure databases

ProteinModelPortali Q2YNH6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 359391.BAB1_0844.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ10800 ; CAJ10800 ; BAB1_0844 .
GeneIDi 3788778.
KEGGi bmf:BAB1_0844.
PATRICi 17844601. VBIBruMel86222_0879.

Phylogenomic databases

eggNOGi COG1136.
KOi K09810.
OMAi YNRGRPG.
OrthoDBi EOG6T7N3V.

Enzyme and pathway databases

BioCyci BABO359391:GKDV-858-MONOMER.
BMEL359391:GJOQ-858-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
InterProi IPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR015854. ABC_transpr_LolD.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF00005. ABC_tran. 1 hit.
[Graphical view ]
SMARTi SM00382. AAA. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51244. LOLD. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiLOLD_BRUA2
AccessioniPrimary (citable) accession number: Q2YNH6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: February 7, 2006
Last modified: October 1, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3