Q2YNC0 (PLSX_BRUA2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphate acyltransferase
EC=2.3.1.n2

Alternative name(s):
Acyl-ACP phosphotransacylase
Acyl-[acyl-carrier-protein]--phosphate acyltransferase
Phosphate-acyl-ACP acyltransferase

Gene names

Name:	plsX
Ordered Locus Names:	BAB1_0797

Organism

Brucella abortus (strain 2308) [Complete proteome] [HAMAP]

Taxonomic identifier

359391 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella abortus

Protein attributes

Sequence length	346 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the reversible formation of acyl-phosphate (acyl-PO4) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA By similarity. HAMAP-Rule MF_00019
Catalytic activity	Acyl-[acyl-carrier-protein] + phosphate = acyl-phosphate + [acyl-carrier-protein]. HAMAP-Rule MF_00019
Pathway	Lipid metabolism; phospholipid metabolism. HAMAP-Rule MF_00019
Subunit structure	Homodimer. Probably interacts with PlsY By similarity.
Subcellular location	Cytoplasm By similarity. Note: Associated with the membrane possibly through PlsY By similarity.
Sequence similarities	Belongs to the PlsX family.

Ontologies

Keywords
Biological process	Lipid biosynthesis Lipid metabolism Phospholipid biosynthesis Phospholipid metabolism
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	fatty acid biosynthetic process Inferred from electronic annotation. Source: HAMAP phospholipid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro transferase activity, transferring acyl groups other than amino-acyl groups Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 346	346	Phosphate acyltransferase HAMAP-Rule MF_00019		PRO_1000001723

Sequences

	Sequence		Length	Mass (Da)
	Q2YNC0 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: AEE0F20E7F44CE7A	FASTA	346	36,970
	10 20 30 40 50 60 MIKISIDAMG GDFGPEVVIP GAAKAFERHP DIRFIFFGLP AQVEPVLARY PKLKEASEFR 70 80 90 100 110 120 ASEVAIGMDD KPSQALRAGR GKSSMWQAIE AVKTGDADAC VSAGNTGALM AMSKFCLRMM 130 140 150 160 170 180 SDVERPAIAG IWPTLRGESI VLDIGATIGA DARQLVDYAV MGAGMARALF EVRKPTVGLL 190 200 210 220 230 240 NVGTEEVKGL DEIKEAGQIL RDTPLDGLEY SGFVEGNDIG KGTVDVVVTE GFTGNIALKT 250 260 270 280 290 300 AEGTARQMAE LLRQAMSRTL LAKIGYVFAK GAFDRLREKM DPNKVNGGVF LGLSGIVIKS 310 320 330 340 HGGANAEGFC SAVEVGYDMV RNRLLEKIEA DLAHFHHSHS HVSSKA

References

[1]

"Whole-genome analyses of speciation events in pathogenic Brucellae." Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E. Infect. Immun. 73:8353-8361(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 2308.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM040264 Genomic DNA. Translation: CAJ10753.1.
RefSeq	YP_414230.1. NC_007618.1.
3D structure databases
ProteinModelPortal	Q2YNC0.
ModBase	Search...
Protein-protein interaction databases
STRING	359391.BAB1_0797.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAJ10753; CAJ10753; BAB1_0797.
GeneID	3788858.
KEGG	bmf:BAB1_0797.
PATRIC	17844497. VBIBruMel86222_0830.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0416.
HOGENOM	HOG000154730.
KO	K03621.
OMA	DEKPSQA.
ProtClustDB	PRK05331.
Enzyme and pathway databases
BioCyc	BMEL359391:GJOQ-808-MONOMER.
UniPathway	UPA00085.
Family and domain databases
Gene3D	3.40.718.10. 1 hit.
HAMAP	MF_00019. PlsX.
InterPro	IPR003664. FA_synthesis. IPR024084. IsoPropMal-DH-like_dom. IPR012281. Phospholipid_synth_PlsX-like. [Graphical view]
Pfam	PF02504. FA_synthesis. 1 hit. [Graphical view]
PIRSF	PIRSF002465. Phsphlp_syn_PlsX. 1 hit.
TIGRFAMs	TIGR00182. plsX. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PLSX_BRUA2

Accession

Primary (citable) accession number: Q2YNC0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 7, 2006
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program