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Q2YN94

- NRDR_BRUA2

UniProt

Q2YN94 - NRDR_BRUA2

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Protein

Transcriptional repressor NrdR

Gene

nrdR

Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri3 – 3432UniRule annotationAdd
BLAST

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. DNA binding Source: UniProtKB-KW
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. negative regulation of transcription, DNA-templated Source: UniProtKB-HAMAP
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

ATP-binding, DNA-binding, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

BioCyciBABO359391:GKDV-799-MONOMER.
BMEL359391:GJOQ-799-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional repressor NrdRUniRule annotation
Gene namesi
Name:nrdRUniRule annotation
Ordered Locus Names:BAB1_0788
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 158158Transcriptional repressor NrdRPRO_0000230857Add
BLAST

Proteomic databases

PRIDEiQ2YN94.

Interactioni

Protein-protein interaction databases

STRINGi359391.BAB1_0788.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini49 – 13991ATP-coneUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the NrdR family.UniRule annotation
Contains 1 ATP-cone domain.UniRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri3 – 3432UniRule annotationAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiCOG1327.
HOGENOMiHOG000097653.
KOiK07738.
OMAiKRRFTTY.
OrthoDBiEOG6XM7J6.

Family and domain databases

HAMAPiMF_00440. NrdR.
InterProiIPR005144. ATP-cone.
IPR003796. RNR_NrdR-like.
[Graphical view]
PfamiPF03477. ATP-cone. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00244. TIGR00244. 1 hit.
PROSITEiPS51161. ATP_CONE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2YN94-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRCPYCQSED TQVKDSRPAE DGAVIRRRRV CSVCGGRFTT FERVQLRDLM
60 70 80 90 100
VVKKSGRRVP FDRDKLTRSI EVALRKRDVD SERVERAISG IVRQLESAGE
110 120 130 140 150
AEVTSDEIGR LAMDALKGID DIAYIRFASV YRNFSKAVDF HNVIDELTVS

ETGDNLET
Length:158
Mass (Da):17,933
Last modified:February 7, 2006 - v1
Checksum:i04CC792029B47D56
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA. Translation: CAJ10744.1.
RefSeqiYP_414221.1. NC_007618.1.

Genome annotation databases

EnsemblBacteriaiCAJ10744; CAJ10744; BAB1_0788.
GeneIDi3787489.
KEGGibmf:BAB1_0788.
PATRICi17844479. VBIBruMel86222_0821.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA. Translation: CAJ10744.1 .
RefSeqi YP_414221.1. NC_007618.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 359391.BAB1_0788.

Proteomic databases

PRIDEi Q2YN94.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ10744 ; CAJ10744 ; BAB1_0788 .
GeneIDi 3787489.
KEGGi bmf:BAB1_0788.
PATRICi 17844479. VBIBruMel86222_0821.

Phylogenomic databases

eggNOGi COG1327.
HOGENOMi HOG000097653.
KOi K07738.
OMAi KRRFTTY.
OrthoDBi EOG6XM7J6.

Enzyme and pathway databases

BioCyci BABO359391:GKDV-799-MONOMER.
BMEL359391:GJOQ-799-MONOMER.

Family and domain databases

HAMAPi MF_00440. NrdR.
InterProi IPR005144. ATP-cone.
IPR003796. RNR_NrdR-like.
[Graphical view ]
Pfami PF03477. ATP-cone. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00244. TIGR00244. 1 hit.
PROSITEi PS51161. ATP_CONE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiNRDR_BRUA2
AccessioniPrimary (citable) accession number: Q2YN94
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: February 7, 2006
Last modified: November 26, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3