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Protein

Transcriptional repressor NrdR

Gene

nrdR

Organism
Brucella abortus (strain 2308)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri3 – 3432UniRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

ATP-binding, DNA-binding, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

BioCyciBABO359391:GKDV-799-MONOMER.
BMEL359391:GJOQ-799-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional repressor NrdRUniRule annotation
Gene namesi
Name:nrdRUniRule annotation
Ordered Locus Names:BAB1_0788
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719 Componenti: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 158158Transcriptional repressor NrdRPRO_0000230857Add
BLAST

Proteomic databases

PRIDEiQ2YN94.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini49 – 13991ATP-coneUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the NrdR family.UniRule annotation
Contains 1 ATP-cone domain.UniRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri3 – 3432UniRule annotationAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiCOG1327.
HOGENOMiHOG000097653.
KOiK07738.
OMAiSEVAYVR.
OrthoDBiEOG6XM7J6.

Family and domain databases

HAMAPiMF_00440. NrdR.
InterProiIPR005144. ATP-cone.
IPR003796. RNR_NrdR-like.
[Graphical view]
PfamiPF03477. ATP-cone. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00244. TIGR00244. 1 hit.
PROSITEiPS51161. ATP_CONE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2YN94-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRCPYCQSED TQVKDSRPAE DGAVIRRRRV CSVCGGRFTT FERVQLRDLM
60 70 80 90 100
VVKKSGRRVP FDRDKLTRSI EVALRKRDVD SERVERAISG IVRQLESAGE
110 120 130 140 150
AEVTSDEIGR LAMDALKGID DIAYIRFASV YRNFSKAVDF HNVIDELTVS

ETGDNLET
Length:158
Mass (Da):17,933
Last modified:February 7, 2006 - v1
Checksum:i04CC792029B47D56
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA. Translation: CAJ10744.1.
RefSeqiWP_002966765.1. NZ_KN046823.1.
YP_414221.1. NC_007618.1.

Genome annotation databases

EnsemblBacteriaiCAJ10744; CAJ10744; BAB1_0788.
GeneIDi3787489.
KEGGibmf:BAB1_0788.
PATRICi17844479. VBIBruMel86222_0821.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA. Translation: CAJ10744.1.
RefSeqiWP_002966765.1. NZ_KN046823.1.
YP_414221.1. NC_007618.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ2YN94.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ10744; CAJ10744; BAB1_0788.
GeneIDi3787489.
KEGGibmf:BAB1_0788.
PATRICi17844479. VBIBruMel86222_0821.

Phylogenomic databases

eggNOGiCOG1327.
HOGENOMiHOG000097653.
KOiK07738.
OMAiSEVAYVR.
OrthoDBiEOG6XM7J6.

Enzyme and pathway databases

BioCyciBABO359391:GKDV-799-MONOMER.
BMEL359391:GJOQ-799-MONOMER.

Family and domain databases

HAMAPiMF_00440. NrdR.
InterProiIPR005144. ATP-cone.
IPR003796. RNR_NrdR-like.
[Graphical view]
PfamiPF03477. ATP-cone. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00244. TIGR00244. 1 hit.
PROSITEiPS51161. ATP_CONE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiNRDR_BRUA2
AccessioniPrimary (citable) accession number: Q2YN94
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: February 7, 2006
Last modified: June 24, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.