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Q2YN94

- NRDR_BRUA2

UniProt

Q2YN94 - NRDR_BRUA2

Protein

Transcriptional repressor NrdR

Gene

nrdR

Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (07 Feb 2006)
      Previous versions | rss
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    Functioni

    Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.UniRule annotation

    Cofactori

    Binds 1 zinc ion.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri3 – 3432UniRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. DNA binding Source: UniProtKB-KW
    3. zinc ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. negative regulation of transcription, DNA-templated Source: UniProtKB-HAMAP
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Repressor

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    ATP-binding, DNA-binding, Metal-binding, Nucleotide-binding, Zinc

    Enzyme and pathway databases

    BioCyciBABO359391:GKDV-799-MONOMER.
    BMEL359391:GJOQ-799-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transcriptional repressor NrdRUniRule annotation
    Gene namesi
    Name:nrdRUniRule annotation
    Ordered Locus Names:BAB1_0788
    OrganismiBrucella abortus (strain 2308)
    Taxonomic identifieri359391 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000002719: Chromosome I

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 158158Transcriptional repressor NrdRPRO_0000230857Add
    BLAST

    Proteomic databases

    PRIDEiQ2YN94.

    Interactioni

    Protein-protein interaction databases

    STRINGi359391.BAB1_0788.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini49 – 13991ATP-coneUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the NrdR family.UniRule annotation
    Contains 1 ATP-cone domain.UniRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri3 – 3432UniRule annotationAdd
    BLAST

    Keywords - Domaini

    Zinc-finger

    Phylogenomic databases

    eggNOGiCOG1327.
    HOGENOMiHOG000097653.
    KOiK07738.
    OMAiKRRFTTY.
    OrthoDBiEOG6XM7J6.

    Family and domain databases

    HAMAPiMF_00440. NrdR.
    InterProiIPR005144. ATP-cone.
    IPR003796. RNR_NrdR-like.
    [Graphical view]
    PfamiPF03477. ATP-cone. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00244. TIGR00244. 1 hit.
    PROSITEiPS51161. ATP_CONE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2YN94-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRCPYCQSED TQVKDSRPAE DGAVIRRRRV CSVCGGRFTT FERVQLRDLM    50
    VVKKSGRRVP FDRDKLTRSI EVALRKRDVD SERVERAISG IVRQLESAGE 100
    AEVTSDEIGR LAMDALKGID DIAYIRFASV YRNFSKAVDF HNVIDELTVS 150
    ETGDNLET 158
    Length:158
    Mass (Da):17,933
    Last modified:February 7, 2006 - v1
    Checksum:i04CC792029B47D56
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM040264 Genomic DNA. Translation: CAJ10744.1.
    RefSeqiYP_414221.1. NC_007618.1.

    Genome annotation databases

    EnsemblBacteriaiCAJ10744; CAJ10744; BAB1_0788.
    GeneIDi3787489.
    KEGGibmf:BAB1_0788.
    PATRICi17844479. VBIBruMel86222_0821.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM040264 Genomic DNA. Translation: CAJ10744.1 .
    RefSeqi YP_414221.1. NC_007618.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 359391.BAB1_0788.

    Proteomic databases

    PRIDEi Q2YN94.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAJ10744 ; CAJ10744 ; BAB1_0788 .
    GeneIDi 3787489.
    KEGGi bmf:BAB1_0788.
    PATRICi 17844479. VBIBruMel86222_0821.

    Phylogenomic databases

    eggNOGi COG1327.
    HOGENOMi HOG000097653.
    KOi K07738.
    OMAi KRRFTTY.
    OrthoDBi EOG6XM7J6.

    Enzyme and pathway databases

    BioCyci BABO359391:GKDV-799-MONOMER.
    BMEL359391:GJOQ-799-MONOMER.

    Family and domain databases

    HAMAPi MF_00440. NrdR.
    InterProi IPR005144. ATP-cone.
    IPR003796. RNR_NrdR-like.
    [Graphical view ]
    Pfami PF03477. ATP-cone. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00244. TIGR00244. 1 hit.
    PROSITEi PS51161. ATP_CONE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 2308.

    Entry informationi

    Entry nameiNRDR_BRUA2
    AccessioniPrimary (citable) accession number: Q2YN94
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2006
    Last sequence update: February 7, 2006
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Brucella abortus strain 2308
      Brucella abortus (strain 2308): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3