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Q2YN94

- NRDR_BRUA2

UniProt

Q2YN94 - NRDR_BRUA2

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Protein

Transcriptional repressor NrdR

Gene
nrdR, BAB1_0788
Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes By similarity.UniRule annotation

Cofactori

Binds 1 zinc ion By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri3 – 3432 By similarityAdd
BLAST

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. DNA binding Source: UniProtKB-KW
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. negative regulation of transcription, DNA-templated Source: UniProtKB-HAMAP
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

ATP-binding, DNA-binding, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

BioCyciBABO359391:GKDV-799-MONOMER.
BMEL359391:GJOQ-799-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional repressor NrdR
Gene namesi
Name:nrdR
Ordered Locus Names:BAB1_0788
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 158158Transcriptional repressor NrdRUniRule annotationPRO_0000230857Add
BLAST

Proteomic databases

PRIDEiQ2YN94.

Interactioni

Protein-protein interaction databases

STRINGi359391.BAB1_0788.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini49 – 13991ATP-coneAdd
BLAST

Sequence similaritiesi

Belongs to the NrdR family.
Contains 1 ATP-cone domain.

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri3 – 3432 By similarityAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiCOG1327.
HOGENOMiHOG000097653.
KOiK07738.
OMAiKRRFTTY.
OrthoDBiEOG6XM7J6.

Family and domain databases

HAMAPiMF_00440. NrdR.
InterProiIPR005144. ATP-cone.
IPR003796. RNR_NrdR-like.
[Graphical view]
PfamiPF03477. ATP-cone. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00244. TIGR00244. 1 hit.
PROSITEiPS51161. ATP_CONE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2YN94-1 [UniParc]FASTAAdd to Basket

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MRCPYCQSED TQVKDSRPAE DGAVIRRRRV CSVCGGRFTT FERVQLRDLM    50
VVKKSGRRVP FDRDKLTRSI EVALRKRDVD SERVERAISG IVRQLESAGE 100
AEVTSDEIGR LAMDALKGID DIAYIRFASV YRNFSKAVDF HNVIDELTVS 150
ETGDNLET 158
Length:158
Mass (Da):17,933
Last modified:February 7, 2006 - v1
Checksum:i04CC792029B47D56
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040264 Genomic DNA. Translation: CAJ10744.1.
RefSeqiYP_414221.1. NC_007618.1.

Genome annotation databases

EnsemblBacteriaiCAJ10744; CAJ10744; BAB1_0788.
GeneIDi3787489.
KEGGibmf:BAB1_0788.
PATRICi17844479. VBIBruMel86222_0821.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040264 Genomic DNA. Translation: CAJ10744.1 .
RefSeqi YP_414221.1. NC_007618.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 359391.BAB1_0788.

Proteomic databases

PRIDEi Q2YN94.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ10744 ; CAJ10744 ; BAB1_0788 .
GeneIDi 3787489.
KEGGi bmf:BAB1_0788.
PATRICi 17844479. VBIBruMel86222_0821.

Phylogenomic databases

eggNOGi COG1327.
HOGENOMi HOG000097653.
KOi K07738.
OMAi KRRFTTY.
OrthoDBi EOG6XM7J6.

Enzyme and pathway databases

BioCyci BABO359391:GKDV-799-MONOMER.
BMEL359391:GJOQ-799-MONOMER.

Family and domain databases

HAMAPi MF_00440. NrdR.
InterProi IPR005144. ATP-cone.
IPR003796. RNR_NrdR-like.
[Graphical view ]
Pfami PF03477. ATP-cone. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00244. TIGR00244. 1 hit.
PROSITEi PS51161. ATP_CONE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiNRDR_BRUA2
AccessioniPrimary (citable) accession number: Q2YN94
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: February 7, 2006
Last modified: May 14, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi