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Protein

UvrABC system protein C

Gene

uvrC

Organism
Brucella abortus (strain 2308)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:BAB1_0720
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000002719 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002274061 – 611UvrABC system protein CAdd BLAST611

Proteomic databases

PRIDEiQ2YN35

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ2YN35
SMRiQ2YN35
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 84GIY-YIGUniRule annotationAdd BLAST79
Domaini194 – 229UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000279961
KOiK03703
OMAiLFPIRQC

Family and domain databases

Gene3Di3.30.420.340, 1 hit
3.40.1440.10, 1 hit
HAMAPiMF_00203 UvrC, 1 hit
InterProiView protein in InterPro
IPR000305 GIY-YIG_endonuc
IPR035901 GIY-YIG_endonuc_sf
IPR003583 Hlx-hairpin-Hlx_DNA-bd_motif
IPR010994 RuvA_2-like
IPR001943 UVR_dom
IPR036876 UVR_dom_sf
IPR004791 UvrC
IPR001162 UvrC_homol_region
IPR038476 UvrC_homol_region_sf
PfamiView protein in Pfam
PF01541 GIY-YIG, 1 hit
PF02151 UVR, 1 hit
PF08459 UvrC_HhH_N, 1 hit
SMARTiView protein in SMART
SM00465 GIYc, 1 hit
SM00278 HhH1, 2 hits
SUPFAMiSSF46600 SSF46600, 1 hit
SSF47781 SSF47781, 1 hit
SSF82771 SSF82771, 1 hit
TIGRFAMsiTIGR00194 uvrC, 1 hit
PROSITEiView protein in PROSITE
PS50164 GIY_YIG, 1 hit
PS50151 UVR, 1 hit
PS50165 UVRC, 1 hit

Sequencei

Sequence statusi: Complete.

Q2YN35-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRLPNNPGV YRMFNSDGGV LYVGKARNLK KRVSNYARGI GHSNRITRMI
60 70 80 90 100
RETVTMEFVV TRTETEALLL EANLIKRLRP RFNVLMRDDK SFPYILLTGG
110 120 130 140 150
HRAPGIFKHR GARSRKGDYF GPFASAGAVG RTINALQRAF LLRTCTDSVF
160 170 180 190 200
ETRTRPCLLY QIKRCSAPCT YEISDEDYAG LVAEAKAFLS GKSQSVKDHL
210 220 230 240 250
AAAMQAASAD LDFEHAAVYR DRLAALSHVQ SHQGINPQTV EEADVFAIHQ
260 270 280 290 300
EGGMTCIQVF FFRTGQNWGN RAYFPKADSS LGPAEVLGAF LSQFYDDKPC
310 320 330 340 350
PKLVLLSETV EEQSLITEAL STRAGHKVQV SVPQRGEKKE LVQHALTNAR
360 370 380 390 400
EALGRRLAET SSQARLLQGL AETFGLPRAP RRIEVYDNSH IMGTNAVGGM
410 420 430 440 450
IVAGPEGFVK NQYRKFNIRS TDITPGDDFG MMREVIERRF SRLVKEHGTP
460 470 480 490 500
AGEVKNPDAF PAWPDVILID GGQGQVGAVR QILGEMGISD LVTAIGIAKG
510 520 530 540 550
VDREAGRERF FMEGKQPFTL PPRDPVLYFI QRLRDEAHRF AIGTHRARRK
560 570 580 590 600
KEIVRNPLDE IAGIGPTRKR ALLHHFGTAK AVSRAAVEDL MQIDGISEAM
610
ARAIHDHFRD K
Length:611
Mass (Da):68,026
Last modified:December 20, 2005 - v1
Checksum:iEF3566F14836AC50
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA Translation: CAJ10676.1

Genome annotation databases

EnsemblBacteriaiCAJ10676; CAJ10676; BAB1_0720
KEGGibmf:BAB1_0720

Similar proteinsi

Entry informationi

Entry nameiUVRC_BRUA2
AccessioniPrimary (citable) accession number: Q2YN35
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: December 20, 2005
Last modified: May 23, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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