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Q2YN35

- UVRC_BRUA2

UniProt

Q2YN35 - UVRC_BRUA2

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Protein

UvrABC system protein C

Gene

uvrC

Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-HAMAP
  2. excinuclease ABC activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. nucleotide-excision repair Source: UniProtKB-HAMAP
  2. SOS response Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Excision nuclease

Keywords - Biological processi

DNA damage, DNA excision, DNA repair, SOS response

Enzyme and pathway databases

BioCyciBABO359391:GKDV-729-MONOMER.
BMEL359391:GJOQ-729-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:BAB1_0720
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719: Chromosome I

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
  2. excinuclease repair complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 611611UvrABC system protein CPRO_0000227406Add
BLAST

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Protein-protein interaction databases

STRINGi359391.BAB1_0720.

Structurei

3D structure databases

ProteinModelPortaliQ2YN35.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini6 – 8479GIY-YIGUniRule annotationAdd
BLAST
Domaini194 – 22936UVRUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation
Contains 1 GIY-YIG domain.UniRule annotation
Contains 1 UVR domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG0322.
HOGENOMiHOG000279961.
KOiK03703.
OMAiQTIASCV.
OrthoDBiEOG6K13R9.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC.
InterProiIPR027299. GIY-YIG_dom.
IPR000305. GIY-YIG_SF.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
[Graphical view]
PfamiPF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
[Graphical view]
SMARTiSM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
[Graphical view]
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiPS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2YN35-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKRLPNNPGV YRMFNSDGGV LYVGKARNLK KRVSNYARGI GHSNRITRMI
60 70 80 90 100
RETVTMEFVV TRTETEALLL EANLIKRLRP RFNVLMRDDK SFPYILLTGG
110 120 130 140 150
HRAPGIFKHR GARSRKGDYF GPFASAGAVG RTINALQRAF LLRTCTDSVF
160 170 180 190 200
ETRTRPCLLY QIKRCSAPCT YEISDEDYAG LVAEAKAFLS GKSQSVKDHL
210 220 230 240 250
AAAMQAASAD LDFEHAAVYR DRLAALSHVQ SHQGINPQTV EEADVFAIHQ
260 270 280 290 300
EGGMTCIQVF FFRTGQNWGN RAYFPKADSS LGPAEVLGAF LSQFYDDKPC
310 320 330 340 350
PKLVLLSETV EEQSLITEAL STRAGHKVQV SVPQRGEKKE LVQHALTNAR
360 370 380 390 400
EALGRRLAET SSQARLLQGL AETFGLPRAP RRIEVYDNSH IMGTNAVGGM
410 420 430 440 450
IVAGPEGFVK NQYRKFNIRS TDITPGDDFG MMREVIERRF SRLVKEHGTP
460 470 480 490 500
AGEVKNPDAF PAWPDVILID GGQGQVGAVR QILGEMGISD LVTAIGIAKG
510 520 530 540 550
VDREAGRERF FMEGKQPFTL PPRDPVLYFI QRLRDEAHRF AIGTHRARRK
560 570 580 590 600
KEIVRNPLDE IAGIGPTRKR ALLHHFGTAK AVSRAAVEDL MQIDGISEAM
610
ARAIHDHFRD K
Length:611
Mass (Da):68,026
Last modified:December 20, 2005 - v1
Checksum:iEF3566F14836AC50
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA. Translation: CAJ10676.1.
RefSeqiYP_414162.2. NC_007618.1.

Genome annotation databases

EnsemblBacteriaiCAJ10676; CAJ10676; BAB1_0720.
GeneIDi3787429.
KEGGibmf:BAB1_0720.
PATRICi17844330. VBIBruMel86222_0748.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA. Translation: CAJ10676.1 .
RefSeqi YP_414162.2. NC_007618.1.

3D structure databases

ProteinModelPortali Q2YN35.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 359391.BAB1_0720.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ10676 ; CAJ10676 ; BAB1_0720 .
GeneIDi 3787429.
KEGGi bmf:BAB1_0720.
PATRICi 17844330. VBIBruMel86222_0748.

Phylogenomic databases

eggNOGi COG0322.
HOGENOMi HOG000279961.
KOi K03703.
OMAi QTIASCV.
OrthoDBi EOG6K13R9.

Enzyme and pathway databases

BioCyci BABO359391:GKDV-729-MONOMER.
BMEL359391:GJOQ-729-MONOMER.

Family and domain databases

Gene3Di 3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPi MF_00203. UvrC.
InterProi IPR027299. GIY-YIG_dom.
IPR000305. GIY-YIG_SF.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
[Graphical view ]
Pfami PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
[Graphical view ]
SMARTi SM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
[Graphical view ]
SUPFAMi SSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsi TIGR00194. uvrC. 1 hit.
PROSITEi PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiUVRC_BRUA2
AccessioniPrimary (citable) accession number: Q2YN35
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: December 20, 2005
Last modified: October 29, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3