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Q2YN35

- UVRC_BRUA2

UniProt

Q2YN35 - UVRC_BRUA2

Protein

UvrABC system protein C

Gene

uvrC

Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 1 (20 Dec 2005)
      Previous versions | rss
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    Functioni

    The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-HAMAP
    2. excinuclease ABC activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. nucleotide-excision repair Source: UniProtKB-HAMAP
    2. SOS response Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Excision nuclease

    Keywords - Biological processi

    DNA damage, DNA excision, DNA repair, SOS response

    Enzyme and pathway databases

    BioCyciBABO359391:GKDV-729-MONOMER.
    BMEL359391:GJOQ-729-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UvrABC system protein CUniRule annotation
    Short name:
    Protein UvrCUniRule annotation
    Alternative name(s):
    Excinuclease ABC subunit CUniRule annotation
    Gene namesi
    Name:uvrCUniRule annotation
    Ordered Locus Names:BAB1_0720
    OrganismiBrucella abortus (strain 2308)
    Taxonomic identifieri359391 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000002719: Chromosome I

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. excinuclease repair complex Source: InterPro

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 611611UvrABC system protein CPRO_0000227406Add
    BLAST

    Interactioni

    Subunit structurei

    Interacts with UvrB in an incision complex.UniRule annotation

    Protein-protein interaction databases

    STRINGi359391.BAB1_0720.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2YN35.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini6 – 8479GIY-YIGUniRule annotationAdd
    BLAST
    Domaini194 – 22936UVRUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the UvrC family.UniRule annotation
    Contains 1 GIY-YIG domain.UniRule annotation
    Contains 1 UVR domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0322.
    HOGENOMiHOG000279961.
    KOiK03703.
    OMAiQTIASCV.
    OrthoDBiEOG6K13R9.

    Family and domain databases

    Gene3Di3.40.1440.10. 1 hit.
    4.10.860.10. 1 hit.
    HAMAPiMF_00203. UvrC.
    InterProiIPR027299. GIY-YIG_dom.
    IPR000305. GIY-YIG_SF.
    IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
    IPR010994. RuvA_2-like.
    IPR001943. UVR_dom.
    IPR004791. UvrC.
    IPR001162. UvrC_homol_region.
    [Graphical view]
    PfamiPF01541. GIY-YIG. 1 hit.
    PF02151. UVR. 1 hit.
    PF08459. UvrC_HhH_N. 1 hit.
    [Graphical view]
    SMARTiSM00465. GIYc. 1 hit.
    SM00278. HhH1. 2 hits.
    [Graphical view]
    SUPFAMiSSF46600. SSF46600. 1 hit.
    SSF47781. SSF47781. 1 hit.
    SSF82771. SSF82771. 1 hit.
    TIGRFAMsiTIGR00194. uvrC. 1 hit.
    PROSITEiPS50164. GIY_YIG. 1 hit.
    PS50151. UVR. 1 hit.
    PS50165. UVRC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2YN35-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKRLPNNPGV YRMFNSDGGV LYVGKARNLK KRVSNYARGI GHSNRITRMI    50
    RETVTMEFVV TRTETEALLL EANLIKRLRP RFNVLMRDDK SFPYILLTGG 100
    HRAPGIFKHR GARSRKGDYF GPFASAGAVG RTINALQRAF LLRTCTDSVF 150
    ETRTRPCLLY QIKRCSAPCT YEISDEDYAG LVAEAKAFLS GKSQSVKDHL 200
    AAAMQAASAD LDFEHAAVYR DRLAALSHVQ SHQGINPQTV EEADVFAIHQ 250
    EGGMTCIQVF FFRTGQNWGN RAYFPKADSS LGPAEVLGAF LSQFYDDKPC 300
    PKLVLLSETV EEQSLITEAL STRAGHKVQV SVPQRGEKKE LVQHALTNAR 350
    EALGRRLAET SSQARLLQGL AETFGLPRAP RRIEVYDNSH IMGTNAVGGM 400
    IVAGPEGFVK NQYRKFNIRS TDITPGDDFG MMREVIERRF SRLVKEHGTP 450
    AGEVKNPDAF PAWPDVILID GGQGQVGAVR QILGEMGISD LVTAIGIAKG 500
    VDREAGRERF FMEGKQPFTL PPRDPVLYFI QRLRDEAHRF AIGTHRARRK 550
    KEIVRNPLDE IAGIGPTRKR ALLHHFGTAK AVSRAAVEDL MQIDGISEAM 600
    ARAIHDHFRD K 611
    Length:611
    Mass (Da):68,026
    Last modified:December 20, 2005 - v1
    Checksum:iEF3566F14836AC50
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM040264 Genomic DNA. Translation: CAJ10676.1.
    RefSeqiYP_414162.2. NC_007618.1.

    Genome annotation databases

    EnsemblBacteriaiCAJ10676; CAJ10676; BAB1_0720.
    GeneIDi3787429.
    KEGGibmf:BAB1_0720.
    PATRICi17844330. VBIBruMel86222_0748.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM040264 Genomic DNA. Translation: CAJ10676.1 .
    RefSeqi YP_414162.2. NC_007618.1.

    3D structure databases

    ProteinModelPortali Q2YN35.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 359391.BAB1_0720.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAJ10676 ; CAJ10676 ; BAB1_0720 .
    GeneIDi 3787429.
    KEGGi bmf:BAB1_0720.
    PATRICi 17844330. VBIBruMel86222_0748.

    Phylogenomic databases

    eggNOGi COG0322.
    HOGENOMi HOG000279961.
    KOi K03703.
    OMAi QTIASCV.
    OrthoDBi EOG6K13R9.

    Enzyme and pathway databases

    BioCyci BABO359391:GKDV-729-MONOMER.
    BMEL359391:GJOQ-729-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1440.10. 1 hit.
    4.10.860.10. 1 hit.
    HAMAPi MF_00203. UvrC.
    InterProi IPR027299. GIY-YIG_dom.
    IPR000305. GIY-YIG_SF.
    IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
    IPR010994. RuvA_2-like.
    IPR001943. UVR_dom.
    IPR004791. UvrC.
    IPR001162. UvrC_homol_region.
    [Graphical view ]
    Pfami PF01541. GIY-YIG. 1 hit.
    PF02151. UVR. 1 hit.
    PF08459. UvrC_HhH_N. 1 hit.
    [Graphical view ]
    SMARTi SM00465. GIYc. 1 hit.
    SM00278. HhH1. 2 hits.
    [Graphical view ]
    SUPFAMi SSF46600. SSF46600. 1 hit.
    SSF47781. SSF47781. 1 hit.
    SSF82771. SSF82771. 1 hit.
    TIGRFAMsi TIGR00194. uvrC. 1 hit.
    PROSITEi PS50164. GIY_YIG. 1 hit.
    PS50151. UVR. 1 hit.
    PS50165. UVRC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 2308.

    Entry informationi

    Entry nameiUVRC_BRUA2
    AccessioniPrimary (citable) accession number: Q2YN35
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 7, 2006
    Last sequence update: December 20, 2005
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Brucella abortus strain 2308
      Brucella abortus (strain 2308): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3