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Q2YN35

- UVRC_BRUA2

UniProt

Q2YN35 - UVRC_BRUA2

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Protein
UvrABC system protein C
Gene
uvrC, BAB1_0720
Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision By similarity.UniRule annotation

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-HAMAP
  2. excinuclease ABC activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. SOS response Source: UniProtKB-HAMAP
  2. nucleotide-excision repair Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Excision nuclease

Keywords - Biological processi

DNA damage, DNA excision, DNA repair, SOS response

Enzyme and pathway databases

BioCyciBABO359391:GKDV-729-MONOMER.
BMEL359391:GJOQ-729-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein C
Short name:
Protein UvrC
Alternative name(s):
Excinuclease ABC subunit C
Gene namesi
Name:uvrC
Ordered Locus Names:BAB1_0720
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719: Chromosome I

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. excinuclease repair complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 611611UvrABC system protein CUniRule annotation
PRO_0000227406Add
BLAST

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex By similarity.

Protein-protein interaction databases

STRINGi359391.BAB1_0720.

Structurei

3D structure databases

ProteinModelPortaliQ2YN35.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini6 – 8479GIY-YIG
Add
BLAST
Domaini194 – 22936UVR
Add
BLAST

Sequence similaritiesi

Belongs to the UvrC family.
Contains 1 GIY-YIG domain.
Contains 1 UVR domain.

Phylogenomic databases

eggNOGiCOG0322.
HOGENOMiHOG000279961.
KOiK03703.
OMAiQTIASCV.
OrthoDBiEOG6K13R9.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC.
InterProiIPR027299. GIY-YIG_dom.
IPR000305. GIY-YIG_SF.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
[Graphical view]
PfamiPF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
[Graphical view]
SMARTiSM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
[Graphical view]
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiPS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2YN35-1 [UniParc]FASTAAdd to Basket

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MKRLPNNPGV YRMFNSDGGV LYVGKARNLK KRVSNYARGI GHSNRITRMI    50
RETVTMEFVV TRTETEALLL EANLIKRLRP RFNVLMRDDK SFPYILLTGG 100
HRAPGIFKHR GARSRKGDYF GPFASAGAVG RTINALQRAF LLRTCTDSVF 150
ETRTRPCLLY QIKRCSAPCT YEISDEDYAG LVAEAKAFLS GKSQSVKDHL 200
AAAMQAASAD LDFEHAAVYR DRLAALSHVQ SHQGINPQTV EEADVFAIHQ 250
EGGMTCIQVF FFRTGQNWGN RAYFPKADSS LGPAEVLGAF LSQFYDDKPC 300
PKLVLLSETV EEQSLITEAL STRAGHKVQV SVPQRGEKKE LVQHALTNAR 350
EALGRRLAET SSQARLLQGL AETFGLPRAP RRIEVYDNSH IMGTNAVGGM 400
IVAGPEGFVK NQYRKFNIRS TDITPGDDFG MMREVIERRF SRLVKEHGTP 450
AGEVKNPDAF PAWPDVILID GGQGQVGAVR QILGEMGISD LVTAIGIAKG 500
VDREAGRERF FMEGKQPFTL PPRDPVLYFI QRLRDEAHRF AIGTHRARRK 550
KEIVRNPLDE IAGIGPTRKR ALLHHFGTAK AVSRAAVEDL MQIDGISEAM 600
ARAIHDHFRD K 611
Length:611
Mass (Da):68,026
Last modified:December 20, 2005 - v1
Checksum:iEF3566F14836AC50
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040264 Genomic DNA. Translation: CAJ10676.1.
RefSeqiYP_414162.2. NC_007618.1.

Genome annotation databases

EnsemblBacteriaiCAJ10676; CAJ10676; BAB1_0720.
GeneIDi3787429.
KEGGibmf:BAB1_0720.
PATRICi17844330. VBIBruMel86222_0748.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040264 Genomic DNA. Translation: CAJ10676.1 .
RefSeqi YP_414162.2. NC_007618.1.

3D structure databases

ProteinModelPortali Q2YN35.
ModBasei Search...

Protein-protein interaction databases

STRINGi 359391.BAB1_0720.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ10676 ; CAJ10676 ; BAB1_0720 .
GeneIDi 3787429.
KEGGi bmf:BAB1_0720.
PATRICi 17844330. VBIBruMel86222_0748.

Phylogenomic databases

eggNOGi COG0322.
HOGENOMi HOG000279961.
KOi K03703.
OMAi QTIASCV.
OrthoDBi EOG6K13R9.

Enzyme and pathway databases

BioCyci BABO359391:GKDV-729-MONOMER.
BMEL359391:GJOQ-729-MONOMER.

Family and domain databases

Gene3Di 3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPi MF_00203. UvrC.
InterProi IPR027299. GIY-YIG_dom.
IPR000305. GIY-YIG_SF.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
[Graphical view ]
Pfami PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
[Graphical view ]
SMARTi SM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
[Graphical view ]
SUPFAMi SSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsi TIGR00194. uvrC. 1 hit.
PROSITEi PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiUVRC_BRUA2
AccessioniPrimary (citable) accession number: Q2YN35
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: December 20, 2005
Last modified: May 14, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi