Q2YN12 (RPOZ_BRUA2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase subunit omega
Short name=RNAP omega subunit
EC=2.7.7.6

Alternative name(s):
RNA polymerase omega subunit
Transcriptase subunit omega

Gene names

Name:	rpoZ
Ordered Locus Names:	BAB1_0671

Organism

Brucella abortus (strain 2308) [Complete proteome] [HAMAP]

Taxonomic identifier

359391 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	133 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits By similarity. HAMAP MF_00366
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP MF_00366
Subunit structure	The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.
Sequence similarities	Belongs to the RNA polymerase subunit omega family.

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	RNA polymerase complex Inferred from electronic annotation. Source: InterPro
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 133	133	DNA-directed RNA polymerase subunit omega HAMAP MF_00366		PRO_0000237441

Sequences

	Sequence		Length	Mass (Da)
	Q2YN12 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 0F6191D6B99842B0	FASTA	133	14,514
	10 20 30 40 50 60 MARVTVEDCV DKVENRFELV LLAGHRARQI SQGAPITVDR DNDKNPVVAL REIADETLSP 70 80 90 100 110 120 DDLKEDLIHS LQKHVEVDEP EAAPAQIANA AEEIAEGIAE AGEEDVVTFD RMSEEELLAG 130 IEGLVAPEKN DGF

References

[1]

"Whole-genome analyses of speciation events in pathogenic Brucellae." Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E. Infect. Immun. 73:8353-8361(2005) [PubMed: 16299333] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 2308.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM040264 Genomic DNA. Translation: CAJ10627.1.
RefSeq	YP_414113.1. NC_007618.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q2YN12.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3787391.
GenomeReviews	Gene locus BAB1_0671 in contig AM040264_GR.
KEGG	bmf:BAB1_0671.
PATRIC	17844236. VBIBruMel86222_0701.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1758.
HOGENOM	HBG742204.
OMA	KVDNRFE.
ProtClustDB	PRK00392.
Enzyme and pathway databases
BioCyc	BMEL359391:BAB1_0671-MONOMER.
Family and domain databases
HAMAP	MF_00366. RNApol_bact_RpoZ. [Tree]
InterPro	IPR003716. DNA-dir_RNA_pol_omega. IPR006110. RNA_poly_omega/K/RPABC2. IPR012293. RNAP_RPB6_omega. [Graphical view]
Gene3D	G3DSA:3.90.940.10. RNAP_RPB6_omega. 1 hit.
KO	K03060.
Pfam	PF01192. RNA_pol_Rpb6. 1 hit. [Graphical view]
SUPFAM	SSF63562. RNA_pol_omega. 1 hit.
TIGRFAMs	TIGR00690. RpoZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPOZ_BRUA2

Accession

Primary (citable) accession number: Q2YN12

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2006
Last sequence update:	February 7, 2006
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program