Q2YN02 (RNC_BRUA2) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 43.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Ribonuclease 3 EC=3.1.26.3 Alternative name(s): Ribonuclease III Short name=RNase III | ||||
| Gene names |
| ||||
| Organism | Brucella abortus (strain 2308) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 359391 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › ![]() |
Protein attributes
| Sequence length | 245 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon By similarity. HAMAP-Rule MF_00104 |
| Catalytic activity | Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP-Rule MF_00104 |
| Cofactor | Mg2+ By similarity. |
| Subunit structure | Homodimer By similarity. |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Contains 1 DRBM (double-stranded RNA-binding) domain. Contains 1 RNase III domain. |
Ontologies
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 245 | 245 | Ribonuclease 3 HAMAP-Rule MF_00104 | PRO_0000228510 | |||||
Regions | |||||||||
| Domain | 19 – 144 | 126 | RNase III | ||||||
| Domain | 169 – 238 | 70 | DRBM | ||||||
Sites | |||||||||
| Active site | 61 | 1 | Potential | ||||||
| Active site | 133 | 1 | By similarity | ||||||
| Metal binding | 57 | 1 | Magnesium By similarity | ||||||
| Metal binding | 130 | 1 | Magnesium By similarity | ||||||
| Metal binding | 133 | 1 | Magnesium By similarity | ||||||
Sequences
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References
| [1] | "Whole-genome analyses of speciation events in pathogenic Brucellae." Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E. Infect. Immun. 73:8353-8361(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 2308. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AM040264 Genomic DNA. Translation: CAJ10637.1. |
| RefSeq | YP_414123.1. NC_007618.1. |
3D structure databases | |
| ProteinModelPortal | Q2YN02. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 359391.BAB1_0681. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | CAJ10637; CAJ10637; BAB1_0681. |
| GeneID | 3788905. |
| KEGG | bmf:BAB1_0681. |
| PATRIC | 17844256. VBIBruMel86222_0711. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0571. |
| HOGENOM | HOG000246809. |
| KO | K03685. |
| OMA | LTHKSCK. |
| ProtClustDB | PRK12371. |
Enzyme and pathway databases | |
| BioCyc | BMEL359391:GJOQ-690-MONOMER. |
Family and domain databases | |
| Gene3D | 1.10.1520.10. 1 hit. 3.30.160.20. 1 hit. |
| HAMAP | MF_00104. RNase_III. |
| InterPro | IPR001159. Ds-RNA-bd. IPR014720. dsRNA-bd-like_dom. IPR011907. RNase_III. IPR000999. RNase_III_dom. [Graphical view] |
| PANTHER | PTHR11207. PTHR11207. 1 hit. |
| Pfam | PF00035. dsrm. 1 hit. PF00636. Ribonuclease_3. 1 hit. [Graphical view] |
| SMART | SM00358. DSRM. 1 hit. SM00535. RIBOc. 1 hit. [Graphical view] |
| SUPFAM | SSF69065. RNase_III. 1 hit. |
| TIGRFAMs | TIGR02191. RNaseIII. 1 hit. |
| PROSITE | PS50137. DS_RBD. 1 hit. PS00517. RNASE_3_1. 1 hit. PS50142. RNASE_3_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | RNC_BRUA2 | ||||||||
| Accession | Primary (citable) accession number: Q2YN02 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Brucella abortus strain 2308 Brucella abortus (strain 2308): entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with
