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Protein

Ureidoglycolate lyase

Gene

allA

Organism
Brucella abortus (strain 2308)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.UniRule annotation

Catalytic activityi

(S)-ureidoglycolate = glyoxylate + urea.UniRule annotation

Cofactori

Ni2+UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ureidoglycolate hydrolase activity Source: InterPro
  2. ureidoglycolate lyase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. allantoin catabolic process Source: UniProtKB-HAMAP
  2. purine nucleobase catabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Purine metabolism

Enzyme and pathway databases

BioCyciBABO359391:GKDV-538-MONOMER.
BMEL359391:GJOQ-538-MONOMER.
UniPathwayiUPA00395.

Names & Taxonomyi

Protein namesi
Recommended name:
Ureidoglycolate lyaseUniRule annotation (EC:4.3.2.3UniRule annotation)
Alternative name(s):
UreidoglycolataseUniRule annotation
Gene namesi
Name:allAUniRule annotation
Ordered Locus Names:BAB1_0531
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 169169Ureidoglycolate lyasePRO_1000061344Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi359391.BAB1_0531.

Structurei

3D structure databases

ProteinModelPortaliQ2YMM3.
SMRiQ2YMM3. Positions 4-159.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ureidoglycolate lyase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG3194.
HOGENOMiHOG000256169.
KOiK01483.
OMAiNCDIFQF.
OrthoDBiEOG6JX7JB.

Family and domain databases

Gene3Di2.60.120.480. 1 hit.
HAMAPiMF_00616. Ureidogly_lyase.
InterProiIPR011051. RmlC_Cupin.
IPR007247. Ureidogly_hydro.
IPR023525. Ureidogly_hydro_bac.
IPR024060. Ureidoglycolate_hydrolase_dom.
[Graphical view]
PANTHERiPTHR21221. PTHR21221. 1 hit.
PfamiPF04115. Ureidogly_hydro. 1 hit.
[Graphical view]
PIRSFiPIRSF017306. Ureidogly_hydro. 1 hit.
SUPFAMiSSF51182. SSF51182. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2YMM3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQIETLTVEP LTKEAFAPFG DVIEVEGAQL RLINNGTTER YHDLARMEAA
60 70 80 90 100
GTQTRVLINI FRGQSFAAPI DIMMMERHPF GSQAFIPLNG RPFLVVVAED
110 120 130 140 150
AGAGPARPRA FLARGDQGVN YLRNIWHHPL LALEQKSDFL VVDRAGREDN
160
LEEYFFSDYA YRIETTQTA
Length:169
Mass (Da):19,043
Last modified:February 7, 2006 - v1
Checksum:i9D42DFA9E69C3EDB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA. Translation: CAJ10487.1.
RefSeqiYP_413985.1. NC_007618.1.

Genome annotation databases

EnsemblBacteriaiCAJ10487; CAJ10487; BAB1_0531.
GeneIDi3787263.
KEGGibmf:BAB1_0531.
PATRICi17843938. VBIBruMel86222_0554.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA. Translation: CAJ10487.1.
RefSeqiYP_413985.1. NC_007618.1.

3D structure databases

ProteinModelPortaliQ2YMM3.
SMRiQ2YMM3. Positions 4-159.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi359391.BAB1_0531.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ10487; CAJ10487; BAB1_0531.
GeneIDi3787263.
KEGGibmf:BAB1_0531.
PATRICi17843938. VBIBruMel86222_0554.

Phylogenomic databases

eggNOGiCOG3194.
HOGENOMiHOG000256169.
KOiK01483.
OMAiNCDIFQF.
OrthoDBiEOG6JX7JB.

Enzyme and pathway databases

UniPathwayiUPA00395.
BioCyciBABO359391:GKDV-538-MONOMER.
BMEL359391:GJOQ-538-MONOMER.

Family and domain databases

Gene3Di2.60.120.480. 1 hit.
HAMAPiMF_00616. Ureidogly_lyase.
InterProiIPR011051. RmlC_Cupin.
IPR007247. Ureidogly_hydro.
IPR023525. Ureidogly_hydro_bac.
IPR024060. Ureidoglycolate_hydrolase_dom.
[Graphical view]
PANTHERiPTHR21221. PTHR21221. 1 hit.
PfamiPF04115. Ureidogly_hydro. 1 hit.
[Graphical view]
PIRSFiPIRSF017306. Ureidogly_hydro. 1 hit.
SUPFAMiSSF51182. SSF51182. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiALLA_BRUA2
AccessioniPrimary (citable) accession number: Q2YMM3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 7, 2006
Last modified: February 4, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.