Q2YMM3 (ALLA_BRUA2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ureidoglycolate hydrolase
EC=3.5.3.19

Gene names

Name:	allA
Ordered Locus Names:	BAB1_0531

Organism

Brucella abortus (strain 2308) [Complete proteome] [HAMAP]

Taxonomic identifier

359391 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella abortus

Protein attributes

Sequence length	169 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-ureidoglycolate + H2O = glyoxylate + 2 NH3 + CO2. HAMAP-Rule MF_00616
Pathway	Nitrogen metabolism; (S)-allantoin degradation; glyoxylate from (S)-ureidoglycolate: step 1/1. HAMAP-Rule MF_00616
Subunit structure	Homodimer By similarity. HAMAP-Rule MF_00616
Sequence similarities	Belongs to the ureidoglycolate hydrolase family.

Ontologies

Keywords
Biological process	Purine metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	allantoin catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway purine nucleobase metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ureidoglycolate hydrolase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 169	169	Ureidoglycolate hydrolase HAMAP-Rule MF_00616		PRO_1000061344

Sequences

	Sequence		Length	Mass (Da)
	Q2YMM3 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 9D42DFA9E69C3EDB	FASTA	169	19,043
	10 20 30 40 50 60 MQIETLTVEP LTKEAFAPFG DVIEVEGAQL RLINNGTTER YHDLARMEAA GTQTRVLINI 70 80 90 100 110 120 FRGQSFAAPI DIMMMERHPF GSQAFIPLNG RPFLVVVAED AGAGPARPRA FLARGDQGVN 130 140 150 160 YLRNIWHHPL LALEQKSDFL VVDRAGREDN LEEYFFSDYA YRIETTQTA

References

[1]

"Whole-genome analyses of speciation events in pathogenic Brucellae." Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E. Infect. Immun. 73:8353-8361(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 2308.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM040264 Genomic DNA. Translation: CAJ10487.1.
RefSeq	YP_413985.1. NC_007618.1.
3D structure databases
ProteinModelPortal	Q2YMM3.
SMR	Q2YMM3. Positions 4-159.
ModBase	Search...
Protein-protein interaction databases
STRING	359391.BAB1_0531.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAJ10487; CAJ10487; BAB1_0531.
GeneID	3787263.
KEGG	bmf:BAB1_0531.
PATRIC	17843938. VBIBruMel86222_0554.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3194.
HOGENOM	HOG000256169.
KO	K01483.
OMA	SQAFIPM.
ProtClustDB	PRK03606.
Enzyme and pathway databases
BioCyc	BMEL359391:GJOQ-538-MONOMER.
UniPathway	UPA00395; UER00656.
Family and domain databases
Gene3D	2.60.120.480. 1 hit.
HAMAP	MF_00616. Ureidogly_hydro.
InterPro	IPR011051. RmlC_Cupin. IPR007247. Ureidogly_hydro. IPR023525. Ureidogly_hydro_bac. IPR024060. Ureidoglycolate_hydrolase_dom. [Graphical view]
PANTHER	PTHR21221. PTHR21221. 1 hit.
Pfam	PF04115. Ureidogly_hydro. 1 hit. [Graphical view]
PIRSF	PIRSF017306. Ureidogly_hydro. 1 hit.
SUPFAM	SSF51182. RmlC_like_cupin. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALLA_BRUA2

Accession

Primary (citable) accession number: Q2YMM3

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	February 7, 2006
Last modified:	May 29, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program