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Q2YMM3 (ALLA_BRUA2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ureidoglycolate lyase

EC=4.3.2.3
Alternative name(s):
Ureidoglycolatase
Gene names
Name:allA
Ordered Locus Names:BAB1_0531
OrganismBrucella abortus (strain 2308) [Complete proteome] [HAMAP]
Taxonomic identifier359391 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length169 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source By similarity. HAMAP-Rule MF_00616

Catalytic activity

(S)-ureidoglycolate = glyoxylate + urea. HAMAP-Rule MF_00616

Cofactor

Nickel By similarity. HAMAP-Rule MF_00616

Pathway

Nitrogen metabolism; (S)-allantoin degradation. HAMAP-Rule MF_00616

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00616

Sequence similarities

Belongs to the ureidoglycolate lyase family.

Ontologies

Keywords
   Biological processPurine metabolism
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processallantoin catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

purine nucleobase metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionureidoglycolate hydrolase activity

Inferred from electronic annotation. Source: InterPro

ureidoglycolate lyase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 169169Ureidoglycolate lyase HAMAP-Rule MF_00616
PRO_1000061344

Sequences

Sequence LengthMass (Da)Tools
Q2YMM3 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: 9D42DFA9E69C3EDB

FASTA16919,043
        10         20         30         40         50         60 
MQIETLTVEP LTKEAFAPFG DVIEVEGAQL RLINNGTTER YHDLARMEAA GTQTRVLINI 

        70         80         90        100        110        120 
FRGQSFAAPI DIMMMERHPF GSQAFIPLNG RPFLVVVAED AGAGPARPRA FLARGDQGVN 

       130        140        150        160 
YLRNIWHHPL LALEQKSDFL VVDRAGREDN LEEYFFSDYA YRIETTQTA 

« Hide

References

[1]"Whole-genome analyses of speciation events in pathogenic Brucellae."
Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.
Infect. Immun. 73:8353-8361(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 2308.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM040264 Genomic DNA. Translation: CAJ10487.1.
RefSeqYP_413985.1. NC_007618.1.

3D structure databases

ProteinModelPortalQ2YMM3.
SMRQ2YMM3. Positions 4-159.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING359391.BAB1_0531.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ10487; CAJ10487; BAB1_0531.
GeneID3787263.
KEGGbmf:BAB1_0531.
PATRIC17843938. VBIBruMel86222_0554.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3194.
HOGENOMHOG000256169.
KOK01483.
OMANCDIFQF.
OrthoDBEOG6JX7JB.

Enzyme and pathway databases

BioCycBABO359391:GKDV-538-MONOMER.
BMEL359391:GJOQ-538-MONOMER.
UniPathwayUPA00395.

Family and domain databases

Gene3D2.60.120.480. 1 hit.
HAMAPMF_00616. Ureidogly_lyase.
InterProIPR011051. RmlC_Cupin.
IPR007247. Ureidogly_hydro.
IPR023525. Ureidogly_hydro_bac.
IPR024060. Ureidoglycolate_hydrolase_dom.
[Graphical view]
PANTHERPTHR21221. PTHR21221. 1 hit.
PfamPF04115. Ureidogly_hydro. 1 hit.
[Graphical view]
PIRSFPIRSF017306. Ureidogly_hydro. 1 hit.
SUPFAMSSF51182. SSF51182. 1 hit.
ProtoNetSearch...

Entry information

Entry nameALLA_BRUA2
AccessionPrimary (citable) accession number: Q2YMM3
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 7, 2006
Last modified: May 14, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Brucella abortus strain 2308

Brucella abortus (strain 2308): entries and gene names