Reviewed, UniProtKB/Swiss-Prot Q2YMG5 (ACP_BRUA2)

Names and origin

Protein names

Recommended name:
    Acyl carrier protein
      Short name=ACP

Gene names

Name:	acpP
Ordered Locus Names:	BAB1_0484

Organism

Brucella abortus (strain 2308) [Complete proteome] [HAMAP]

Taxonomic identifier

359391 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	78 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Carrier of the growing fatty acid chain in fatty acid biosynthesis By similarity.
Pathway	Lipid metabolism; fatty acid biosynthesis. HAMAP MF_01217
Subcellular location	Cytoplasm By similarity.
Post-translational modification	4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group By similarity.
Sequence similarities	Contains 1 acyl carrier domain.

Ontologies

Keywords
Biological process	Fatty acid biosynthesis Lipid synthesis
Cellular component	Cytoplasm
Ligand	Phosphopantetheine
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	acyl carrier activity Inferred from electronic annotation. Source: HAMAP cofactor binding Inferred from electronic annotation. Source: InterPro phosphopantetheine binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 78	78	Acyl carrier protein HAMAP MF_01217		PRO_1000066566
Amino acid modifications
	Modified residue	37	1	O-(pantetheine 4'-phosphoryl)serine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2YMG5-1 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 5F2933B306AEE119	FASTA	78	8,301
	10 20 30 40 50 60 MSDTAERVKK IVVEHLGVDA DKVTEGASFI DDLGADSLDT VELVMAFEEE FGVEIPDDAA 70 ETILTVGDAV KFIDKASA

References

[1]

"Whole-genome analyses of speciation events in pathogenic Brucellae." Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E. Infect. Immun. 73:8353-8361(2005) [PubMed: 16299333] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM040264 Genomic DNA. Translation: CAJ10440.1.
RefSeq	YP_413944.1.
3D structure databases
HSSP	HSSP built from PDB template 1X3O based on UniProtKB Q5SL79.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2YMG5.
Genome annotation databases
GeneID	3788609.
GenomeReviews	Gene locus BAB1_0484 in contig AM040264_GR.
KEGG	bmf:BAB1_0484.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q2YMG5.
OMA	IDYITEH
Enzyme and pathway databases
BioCyc	BMEL359391:BAB1_0484-MON.
Family and domain databases
HAMAP	MF_01217. [Tree]
InterPro	IPR003231. Acyl_carrier. IPR009081. Acyl_carrier_prot-like. IPR006163. Phsphopanteth_bd. IPR006162. PPantetheine_attach_site. [Graphical view]
Pfam	PF00550. PP-binding. 1 hit. [Graphical view]
TIGRFAMs	TIGR00517. acyl_carrier. 1 hit.
PROSITE	PS50075. ACP_DOMAIN. 1 hit. PS00012. PHOSPHOPANTETHEINE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACP_BRUA2

Accession

Primary (citable) accession number: Q2YMG5

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	February 7, 2006
Last modified:	November 24, 2009
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)