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Q2YME4 (SYGA_BRUA2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycine--tRNA ligase alpha subunit

EC=6.1.1.14
Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS
Gene names
Name:glyQ
Ordered Locus Names:BAB1_0431
OrganismBrucella abortus (strain 2308) [Complete proteome] [HAMAP]
Taxonomic identifier359391 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length308 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP-Rule MF_00254

Subunit structure

Tetramer of two alpha and two beta subunits By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00254.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glycine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 308308Glycine--tRNA ligase alpha subunit HAMAP-Rule MF_00254
PRO_1000047402

Sequences

Sequence LengthMass (Da)Tools
Q2YME4 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: 6DD60DEDF2F376A7

FASTA30834,945
        10         20         30         40         50         60 
MHPTRSFQGL ILTLHNYWAE HGCAILQPYD MEVGAGTFHP ATTLRSLGPK PWKAAYVQPS 

        70         80         90        100        110        120 
RRPKDGRYGE NPNRLQHYYQ YQVLIKPSPP NLQDLYLGSL KAIGLDPTLH DVRFVEDDWE 

       130        140        150        160        170        180 
SPTLGAWGLG WECWCDGMEV SQFTYFQQVC GIECSPVAGE LTYGLERLAM YVQGVDNVYD 

       190        200        210        220        230        240 
LNFNGLEGDE KVTYGDVFLQ AEQEYSRYNF EMANTETLHQ HFIDAERECE AILKAGSTGE 

       250        260        270        280        290        300 
NSLHKCVFPA YDQCIKASHV FNLMDARGVI SVTERQGYIL RVRNLARQCG EAFLLTDAGG 


FNFKREGE 

« Hide

References

[1]"Whole-genome analyses of speciation events in pathogenic Brucellae."
Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.
Infect. Immun. 73:8353-8361(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 2308.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM040264 Genomic DNA. Translation: CAJ10387.1.
RefSeqYP_413891.1. NC_007618.1.

3D structure databases

ProteinModelPortalQ2YME4.
SMRQ2YME4. Positions 6-297.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING359391.BAB1_0431.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ10387; CAJ10387; BAB1_0431.
GeneID3787190.
KEGGbmf:BAB1_0431.
PATRIC17843732. VBIBruMel86222_0451.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0752.
HOGENOMHOG000264291.
KOK01878.
OMAIQPLDME.
OrthoDBEOG661H9S.

Enzyme and pathway databases

BioCycBABO359391:GKDV-438-MONOMER.
BMEL359391:GJOQ-438-MONOMER.

Family and domain databases

HAMAPMF_00254. Gly_tRNA_synth_alpha.
InterProIPR006194. Gly-tRNA-synth_heterodimer.
IPR002310. Gly-tRNA_ligase_asu.
[Graphical view]
PfamPF02091. tRNA-synt_2e. 1 hit.
[Graphical view]
PRINTSPR01044. TRNASYNTHGA.
TIGRFAMsTIGR00388. glyQ. 1 hit.
PROSITEPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYGA_BRUA2
AccessionPrimary (citable) accession number: Q2YME4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 7, 2006
Last modified: May 14, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella abortus strain 2308

Brucella abortus (strain 2308): entries and gene names

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries