Reviewed, UniProtKB/Swiss-Prot Q2YMC4 (ATPF2_BRUA2)

Names and origin

Protein names

Recommended name:
    ATP synthase subunit b 2
Alternative name(s):
    ATP synthase F(0) sector subunit b 2
    F-type ATPase subunit b 2
      Short name=F-ATPase subunit b 2
    ATPase subunit I 2

Gene names

Name:	atpF2
Ordered Locus Names:	BAB1_0414

Organism

Brucella abortus (strain 2308) [Complete proteome] [HAMAP]

Taxonomic identifier

359391 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	159 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	F1F0 ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F1 containing the extramembraneous catalytic core and F0 containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation By similarity. Component of the F0 channel, it forms part of the peripheral stalk, linking F1 to F0 By similarity.
Subunit structure	F-type ATPases have 2 components, F1 - the catalytic core - and F0 - the membrane proton channel. F1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. F0 has three main subunits: a1, b2 and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F1 is attached to F0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.
Subcellular location	Cell inner membrane; Single-pass membrane protein By similarity.
Sequence similarities	Belongs to the ATPase B chain family.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Cellular component	CF(0) Cell inner membrane Cell membrane Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	ATP synthesis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW proton-transporting ATP synthase complex, coupling factor F(o) Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	hydrogen ion transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 159	159	ATP synthase subunit b 2 HAMAP MF_01398		PRO_0000368366
Regions
	Transmembrane	1 – 21	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q2YMC4-1 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 754831F2EAE583A1	FASTA	159	17,538
	10 20 30 40 50 60 MDATFWAFIA LVIFVAIVVY MKVPGMIGRT LDERADRIKK ELEEARTLRE EAQQLLAEYH 70 80 90 100 110 120 RKRKEAEKEA GDIVASAERE AKALLEEAKR ATEEYVARRN KLAEQKIATA ETDAINAVRA 130 140 150 SAVDLAVAAA GSILAEKVDA KADGNLFNDA LAQVKSHLN

References

[1]

"Whole-genome analyses of speciation events in pathogenic Brucellae." Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E. Infect. Immun. 73:8353-8361(2005) [PubMed: 16299333] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM040264 Genomic DNA. Translation: CAJ10370.1.
RefSeq	YP_413874.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q2YMC4.
Genome annotation databases
GeneID	3788632.
GenomeReviews	Gene locus BAB1_0414 in contig AM040264_GR.
KEGG	bmf:BAB1_0414.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q2YMC4.
OMA	KTEEFVA
Enzyme and pathway databases
BioCyc	BMEL359391:BAB1_0414-MON.
Family and domain databases
HAMAP	MF_01398. [Tree]
InterPro	IPR002146. ATPase_F0-cplx_b/b'su_bac. IPR005864. ATPase_F0-cplx_bsu_bac. [Graphical view]
Pfam	PF00430. ATP-synt_B. 1 hit. [Graphical view]
TIGRFAMs	TIGR01144. ATP_synt_b. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ATPF2_BRUA2

Accession

Primary (citable) accession number: Q2YMC4

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 7, 2006
Last modified:	November 24, 2009
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)