Reviewed, UniProtKB/Swiss-Prot Q2YM98 (ENGA_BRUA2)

Names and origin

Protein names

Recommended name:
    GTP-binding protein engA

Gene names

Name:	engA
Ordered Locus Names:	BAB1_0405

Organism

Brucella abortus (strain 2308) [Complete proteome] [HAMAP]

Taxonomic identifier

359391 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	483 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	GTPase of unknown physiological role. HAMAP MF_00195
Sequence similarities	Belongs to the era/mnmE GTP-binding protein family. EngA subfamily.

Ontologies

Keywords
Domain	Repeat
Ligand	GTP-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	GTP binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 483	483	GTP-binding protein engA HAMAP MF_00195		PRO_1000011575
Regions
	Nucleotide binding	9 – 16	8	GTP 1 Potential
	Nucleotide binding	56 – 60	5	GTP 1 Potential
	Nucleotide binding	119 – 122	4	GTP 1 Potential
	Nucleotide binding	218 – 225	8	GTP 2 Potential
	Nucleotide binding	265 – 269	5	GTP 2 Potential
	Nucleotide binding	330 – 333	4	GTP 2 Potential

Sequences

	Sequence		Length	Mass (Da)
	Q2YM98-1 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 5062657AF4EF8061	FASTA	483	53,297
	10 20 30 40 50 60 MGFTLAIVGR PNVGKSTLFN RLVGRKLALV DDLPGVTRDR RIHDAKLYDL KFQVIDTAGL 70 80 90 100 110 120 EEAANDSLEA RMRAQTEAAI SEADAVLFVI DAKAGITPAD STFAEAVRRS GKPVVLVANK 130 140 150 160 170 180 AEARGSEAGM YDAFQLGLGE PCPISAEHGQ GMPDLRDAIV ELLGEERVFA EERQEEAADE 190 200 210 220 230 240 VFTPAAVGAL VGDDIEDPDA EEIPAYDATK PLRIAIVGRP NAGKSTLINT MLGEDRLLTG 250 260 270 280 290 300 PEAGITRDSI SADWEWHGRK INLFDTAGMR RKARVQEKLE KLSVADSLRA IRFAEVVIIV 310 320 330 340 350 360 LDATIPFEKQ DLQIADLIIR EGRAPVIAFN KWDLIEDRQM VLADLYEKTA RLLPQVRGLR 370 380 390 400 410 420 AVPISGERGQ GIDKLMENVV KTHEIWNRRI STGRLNRWLE GVIAHQPPPA VSGRRLKVKY 430 440 450 460 470 480 MTQVKTRPPG FVVSCSRPDA MPQSYVRYLI NGLRETFDMP GVPIRLSLRT SDNPFAGRAK KKK

References

[1]

"Whole-genome analyses of speciation events in pathogenic Brucellae." Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E. Infect. Immun. 73:8353-8361(2005) [PubMed: 16299333] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM040264 Genomic DNA. Translation: CAJ10361.1.
RefSeq	YP_413865.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q2YM98.
Genome annotation databases
GeneID	3787168.
GenomeReviews	Gene locus BAB1_0405 in contig AM040264_GR.
KEGG	bmf:BAB1_0405.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG592135.
OMA	GLGEPYP.
Enzyme and pathway databases
BioCyc	BMEL359391:BAB1_0405-MON.
Family and domain databases
HAMAP	MF_00195. [Tree]
InterPro	IPR016484. GTP-binding_EngA. IPR006073. GTP1_OBG. IPR015946. KH-like_a/b. IPR002917. MMR_HSR1_GTP_bd. IPR005225. Small_GTP_bd. [Graphical view]
Gene3D	G3DSA:3.30.300.20. KH_prok. 1 hit.
Pfam	PF01926. MMR_HSR1. 2 hits. [Graphical view]
PIRSF	PIRSF006485. GTP-binding_EngA. 1 hit.
PRINTS	PR00326. GTP1OBG.
ProtoNet	Search...

Entry information

Entry name

ENGA_BRUA2

Accession

Primary (citable) accession number: Q2YM98

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 7, 2006
Last modified:	December 15, 2009
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)