Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q2YM57

- APT_BRUA2

UniProt

Q2YM57 - APT_BRUA2

Protein

Adenine phosphoribosyltransferase

Gene

apt

Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 2 (26 Feb 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.UniRule annotation

    Catalytic activityi

    AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. adenine phosphoribosyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. adenine salvage Source: InterPro
    2. AMP salvage Source: UniProtKB-UniPathway
    3. purine ribonucleoside salvage Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Purine salvage

    Enzyme and pathway databases

    BioCyciBABO359391:GKDV-1589-MONOMER.
    BMEL359391:GJOQ-1589-MONOMER.
    UniPathwayiUPA00588; UER00646.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Adenine phosphoribosyltransferaseUniRule annotation (EC:2.4.2.7UniRule annotation)
    Short name:
    APRTUniRule annotation
    Gene namesi
    Name:aptUniRule annotation
    Ordered Locus Names:BAB1_1556
    OrganismiBrucella abortus (strain 2308)
    Taxonomic identifieri359391 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000002719: Chromosome I

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 181181Adenine phosphoribosyltransferasePRO_0000321341Add
    BLAST

    Proteomic databases

    PRIDEiQ2YM57.

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi359391.BAB1_1556.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2YM57.
    SMRiQ2YM57. Positions 8-181.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the purine/pyrimidine phosphoribosyltransferase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0503.
    HOGENOMiHOG000036776.
    KOiK00759.
    OrthoDBiEOG6T4S55.

    Family and domain databases

    Gene3Di3.40.50.2020. 1 hit.
    HAMAPiMF_00004. Aden_phosphoribosyltr.
    InterProiIPR005764. Ade_phspho_trans.
    IPR000836. PRibTrfase_dom.
    IPR029057. PRTase-like.
    [Graphical view]
    PfamiPF00156. Pribosyltran. 1 hit.
    [Graphical view]
    SUPFAMiSSF53271. SSF53271. 1 hit.
    TIGRFAMsiTIGR01090. apt. 1 hit.
    PROSITEiPS00103. PUR_PYR_PR_TRANSFER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2YM57-1 [UniParc]FASTAAdd to Basket

    « Hide

    MESGFKVTLK DAIRTIPDYP KPGVQFRDVT TLMGNAQAFR RAVDELVYPY    50
    AGNRIDKVAG IEARGFILGG AIAHQLSAGF VPIRKKGKLP RDTVRIAYSL 100
    EYGVDEMEMH RDAIEKGERV VLVDDLIATG GTAEAAAKLL LQMGAEIVAA 150
    CFIIDLPDLG GRKKLEALGL PVRTLVAFEG D 181
    Length:181
    Mass (Da):19,614
    Last modified:February 26, 2008 - v2
    Checksum:i128ABF9D88C2A953
    GO

    Sequence cautioni

    The sequence CAJ11512.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM040264 Genomic DNA. Translation: CAJ11512.1. Different initiation.
    RefSeqiYP_414922.1. NC_007618.1.

    Genome annotation databases

    EnsemblBacteriaiCAJ11512; CAJ11512; BAB1_1556.
    GeneIDi3788616.
    KEGGibmf:BAB1_1556.
    PATRICi17846105. VBIBruMel86222_1614.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM040264 Genomic DNA. Translation: CAJ11512.1 . Different initiation.
    RefSeqi YP_414922.1. NC_007618.1.

    3D structure databases

    ProteinModelPortali Q2YM57.
    SMRi Q2YM57. Positions 8-181.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 359391.BAB1_1556.

    Proteomic databases

    PRIDEi Q2YM57.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAJ11512 ; CAJ11512 ; BAB1_1556 .
    GeneIDi 3788616.
    KEGGi bmf:BAB1_1556.
    PATRICi 17846105. VBIBruMel86222_1614.

    Phylogenomic databases

    eggNOGi COG0503.
    HOGENOMi HOG000036776.
    KOi K00759.
    OrthoDBi EOG6T4S55.

    Enzyme and pathway databases

    UniPathwayi UPA00588 ; UER00646 .
    BioCyci BABO359391:GKDV-1589-MONOMER.
    BMEL359391:GJOQ-1589-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.2020. 1 hit.
    HAMAPi MF_00004. Aden_phosphoribosyltr.
    InterProi IPR005764. Ade_phspho_trans.
    IPR000836. PRibTrfase_dom.
    IPR029057. PRTase-like.
    [Graphical view ]
    Pfami PF00156. Pribosyltran. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53271. SSF53271. 1 hit.
    TIGRFAMsi TIGR01090. apt. 1 hit.
    PROSITEi PS00103. PUR_PYR_PR_TRANSFER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 2308.

    Entry informationi

    Entry nameiAPT_BRUA2
    AccessioniPrimary (citable) accession number: Q2YM57
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 26, 2008
    Last sequence update: February 26, 2008
    Last modified: October 1, 2014
    This is version 59 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Brucella abortus strain 2308
      Brucella abortus (strain 2308): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3