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Protein

50S ribosomal protein L7/L12

Gene

rplL

Organism
Brucella abortus (strain 2308)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciBABO359391:GKDV-1287-MONOMER.
BMEL359391:GJOQ-1287-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L7/L12UniRule annotation
Gene namesi
Name:rplLUniRule annotation
Ordered Locus Names:BAB1_1265
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 12412450S ribosomal protein L7/L12PRO_0000243399Add
BLAST

Interactioni

Subunit structurei

Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ2YM14.
SMRiQ2YM14. Positions 6-124.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L7/L12P family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0222.
HOGENOMiHOG000248814.
KOiK02935.
OMAiLEDKWGV.
OrthoDBiEOG6WMJ69.

Family and domain databases

Gene3Di3.30.1390.10. 1 hit.
HAMAPiMF_00368. Ribosomal_L7_L12.
InterProiIPR000206. Ribosomal_L7/12.
IPR014719. Ribosomal_L7/12_C/ClpS-like.
IPR013823. Ribosomal_L7/L12_C.
IPR008932. Ribosomal_L7/L12_oligo.
[Graphical view]
PANTHERiPTHR11809. PTHR11809. 1 hit.
PfamiPF00542. Ribosomal_L12. 1 hit.
[Graphical view]
ProDomiPD001326. Ribosomal_L7/L12_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF48300. SSF48300. 1 hit.
SSF54736. SSF54736. 1 hit.
TIGRFAMsiTIGR00855. L12. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2YM14-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADLAKIVED LSALTVLEAA ELSKLLEEKW GVSAAAPVAV AAAGGAAPAA
60 70 80 90 100
AAEEKTEFDV VLADGGANKI NVIKEVRALT GLGLKEAKDL VEGAPKAVKE
110 120
GASKDEAEKI KAQLEAAGAK VELK
Length:124
Mass (Da):12,546
Last modified:December 20, 2005 - v1
Checksum:iA56E1079AA8BE7F4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA. Translation: CAJ11221.1.
RefSeqiWP_002964371.1. NZ_KN046823.1.
YP_414651.1. NC_007618.1.

Genome annotation databases

EnsemblBacteriaiCAJ11221; CAJ11221; BAB1_1265.
GeneIDi3788918.
KEGGibmf:BAB1_1265.
PATRICi17845491. VBIBruMel86222_1315.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA. Translation: CAJ11221.1.
RefSeqiWP_002964371.1. NZ_KN046823.1.
YP_414651.1. NC_007618.1.

3D structure databases

ProteinModelPortaliQ2YM14.
SMRiQ2YM14. Positions 6-124.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ11221; CAJ11221; BAB1_1265.
GeneIDi3788918.
KEGGibmf:BAB1_1265.
PATRICi17845491. VBIBruMel86222_1315.

Phylogenomic databases

eggNOGiCOG0222.
HOGENOMiHOG000248814.
KOiK02935.
OMAiLEDKWGV.
OrthoDBiEOG6WMJ69.

Enzyme and pathway databases

BioCyciBABO359391:GKDV-1287-MONOMER.
BMEL359391:GJOQ-1287-MONOMER.

Family and domain databases

Gene3Di3.30.1390.10. 1 hit.
HAMAPiMF_00368. Ribosomal_L7_L12.
InterProiIPR000206. Ribosomal_L7/12.
IPR014719. Ribosomal_L7/12_C/ClpS-like.
IPR013823. Ribosomal_L7/L12_C.
IPR008932. Ribosomal_L7/L12_oligo.
[Graphical view]
PANTHERiPTHR11809. PTHR11809. 1 hit.
PfamiPF00542. Ribosomal_L12. 1 hit.
[Graphical view]
ProDomiPD001326. Ribosomal_L7/L12_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF48300. SSF48300. 1 hit.
SSF54736. SSF54736. 1 hit.
TIGRFAMsiTIGR00855. L12. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiRL7_BRUA2
AccessioniPrimary (citable) accession number: Q2YM14
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: December 20, 2005
Last modified: June 24, 2015
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.