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Protein

50S ribosomal protein L7/L12

Gene

rplL

Organism
Brucella abortus (strain 2308)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L7/L12UniRule annotation
Gene namesi
Name:rplLUniRule annotation
Ordered Locus Names:BAB1_1265
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000002719 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002433991 – 12450S ribosomal protein L7/L12Add BLAST124

Proteomic databases

PRIDEiQ2YM14.

Interactioni

Subunit structurei

Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ2YM14.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L7/L12P family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000248814.
KOiK02935.
OMAiEFISNMT.

Family and domain databases

CDDicd00387. Ribosomal_L7_L12. 1 hit.
Gene3Di3.30.1390.10. 1 hit.
HAMAPiMF_00368. Ribosomal_L7_L12. 1 hit.
InterProiIPR000206. Ribosomal_L7/12.
IPR014719. Ribosomal_L7/12_C/ClpS-like.
IPR013823. Ribosomal_L7/L12_C.
IPR008932. Ribosomal_L7/L12_oligo.
[Graphical view]
PfamiPF00542. Ribosomal_L12. 1 hit.
PF16320. Ribosomal_L12_N. 1 hit.
[Graphical view]
ProDomiPD001326. Ribosomal_L7/L12_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF48300. SSF48300. 1 hit.
SSF54736. SSF54736. 1 hit.
TIGRFAMsiTIGR00855. L12. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2YM14-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADLAKIVED LSALTVLEAA ELSKLLEEKW GVSAAAPVAV AAAGGAAPAA
60 70 80 90 100
AAEEKTEFDV VLADGGANKI NVIKEVRALT GLGLKEAKDL VEGAPKAVKE
110 120
GASKDEAEKI KAQLEAAGAK VELK
Length:124
Mass (Da):12,546
Last modified:December 20, 2005 - v1
Checksum:iA56E1079AA8BE7F4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA. Translation: CAJ11221.1.
RefSeqiWP_002964371.1. NZ_KN046823.1.

Genome annotation databases

EnsemblBacteriaiCAJ11221; CAJ11221; BAB1_1265.
GeneIDi3788918.
KEGGibmf:BAB1_1265.
PATRICi17845491. VBIBruMel86222_1315.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA. Translation: CAJ11221.1.
RefSeqiWP_002964371.1. NZ_KN046823.1.

3D structure databases

ProteinModelPortaliQ2YM14.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ2YM14.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ11221; CAJ11221; BAB1_1265.
GeneIDi3788918.
KEGGibmf:BAB1_1265.
PATRICi17845491. VBIBruMel86222_1315.

Phylogenomic databases

HOGENOMiHOG000248814.
KOiK02935.
OMAiEFISNMT.

Family and domain databases

CDDicd00387. Ribosomal_L7_L12. 1 hit.
Gene3Di3.30.1390.10. 1 hit.
HAMAPiMF_00368. Ribosomal_L7_L12. 1 hit.
InterProiIPR000206. Ribosomal_L7/12.
IPR014719. Ribosomal_L7/12_C/ClpS-like.
IPR013823. Ribosomal_L7/L12_C.
IPR008932. Ribosomal_L7/L12_oligo.
[Graphical view]
PfamiPF00542. Ribosomal_L12. 1 hit.
PF16320. Ribosomal_L12_N. 1 hit.
[Graphical view]
ProDomiPD001326. Ribosomal_L7/L12_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF48300. SSF48300. 1 hit.
SSF54736. SSF54736. 1 hit.
TIGRFAMsiTIGR00855. L12. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRL7_BRUA2
AccessioniPrimary (citable) accession number: Q2YM14
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: December 20, 2005
Last modified: November 2, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.