Q2YM03 (RL3_BRUA2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L3

Gene names

Name:	rplC
Ordered Locus Names:	BAB1_1255

Organism

Brucella abortus (strain 2308) [Complete proteome] [HAMAP]

Taxonomic identifier

359391 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella abortus

Protein attributes

Sequence length	237 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit By similarity. HAMAP-Rule MF_01325
Subunit structure	Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19 By similarity.
Post-translational modification	Methylated by PrmB By similarity. HAMAP-Rule MF_01325
Sequence similarities	Belongs to the ribosomal protein L3P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
PTM	Methylation
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 237	237	50S ribosomal protein L3 HAMAP-Rule MF_01325		PRO_0000241324
Amino acid modifications
	Modified residue	151	1	N5-methylglutamine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2YM03 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: C89617EBC6E50AE5	FASTA	237	25,064
	10 20 30 40 50 60 MRSGVIAQKL GMTRVYNDAG EHVPVTVLRM ENCHVVAQRT VEKNGYTAVQ LGVGMAKVKN 70 80 90 100 110 120 TSKAMRGHFA KAEVEPKAKL AEFRVSPDNL LEVGVEITAE HFVAGQKVDV TGTSIGKGFA 130 140 150 160 170 180 GVMKRHNFGG HRASHGNSIT HRSHGSTGQR QDPGKVFKGK KMAGHMGQTR VTTQNIEVVS 190 200 210 220 230 TDSDRGLILV RGAVPGSKGA WILVRDAVKA SLPENAPKPA GLRAGAKAEA AATEGGE

References

[1]

"Whole-genome analyses of speciation events in pathogenic Brucellae." Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E. Infect. Immun. 73:8353-8361(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 2308.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM040264 Genomic DNA. Translation: CAJ11211.1.
RefSeq	YP_414641.1. NC_007618.1.
3D structure databases
ProteinModelPortal	Q2YM03.
SMR	Q2YM03. Positions 4-209.
ModBase	Search...
Protein-protein interaction databases
STRING	359391.BAB1_1255.
Proteomic databases
PRIDE	Q2YM03.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAJ11211; CAJ11211; BAB1_1255.
GeneID	3787853.
KEGG	bmf:BAB1_1255.
PATRIC	17845469. VBIBruMel86222_1304.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0087.
HOGENOM	HOG000100368.
KO	K02906.
OMA	THRAHGS.
ProtClustDB	PRK00001.
Enzyme and pathway databases
BioCyc	BMEL359391:GJOQ-1277-MONOMER.
Family and domain databases
HAMAP	MF_01325_B. Ribosomal_L3_B.
InterPro	IPR000597. Ribosomal_L3. IPR019927. Ribosomal_L3_bac/org-type. IPR019926. Ribosomal_L3_CS. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
PANTHER	PTHR11229. PTHR11229. 1 hit.
Pfam	PF00297. Ribosomal_L3. 1 hit. [Graphical view]
SUPFAM	SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR03625. L3_bact. 1 hit.
PROSITE	PS00474. RIBOSOMAL_L3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL3_BRUA2

Accession

Primary (citable) accession number: Q2YM03

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	February 7, 2006
Last modified:	May 1, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program