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Q2YLZ8

- RS12_BRUA2

UniProt

Q2YLZ8 - RS12_BRUA2

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Protein

30S ribosomal protein S12

Gene
rpsL, BAB1_1260
Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

With S4 and S5 plays an important role in translational accuracy By similarity.UniRule annotation
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit By similarity.UniRule annotation

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-HAMAP
  2. structural constituent of ribosome Source: InterPro
  3. tRNA binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding, tRNA-binding

Enzyme and pathway databases

BioCyciBABO359391:GKDV-1282-MONOMER.
BMEL359391:GJOQ-1282-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S12
Gene namesi
Name:rpsL
Ordered Locus Names:BAB1_1260
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719: Chromosome I

Subcellular locationi

GO - Cellular componenti

  1. small ribosomal subunit Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 12312330S ribosomal protein S12UniRule annotationPRO_0000226378Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei89 – 8913-methylthioaspartic acid By similarity

Proteomic databases

PRIDEiQ2YLZ8.

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex By similarity.

Protein-protein interaction databases

STRINGi359391.BAB1_1260.

Structurei

3D structure databases

ProteinModelPortaliQ2YLZ8.
SMRiQ2YLZ8. Positions 3-123.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0048.
HOGENOMiHOG000040063.
KOiK02950.
OMAiVARSKYG.
OrthoDBiEOG61ZTNF.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00403_B. Ribosomal_S12_B.
InterProiIPR012340. NA-bd_OB-fold.
IPR006032. Ribosomal_S12/S23.
IPR005679. Ribosomal_S12_bac.
[Graphical view]
PANTHERiPTHR11652. PTHR11652. 1 hit.
PfamiPF00164. Ribosom_S12_S23. 1 hit.
[Graphical view]
PIRSFiPIRSF002133. Ribosomal_S12/S23. 1 hit.
PRINTSiPR01034. RIBOSOMALS12.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00981. rpsL_bact. 1 hit.
PROSITEiPS00055. RIBOSOMAL_S12. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2YLZ8-1 [UniParc]FASTAAdd to Basket

« Hide

MPTVNQLIRK PRTAPVKRNK VPALQANPQK RGVCTRVYTT TPKKPNSALR    50
KVAKVRLTNG FEVIGYIPGE GHNLQEHSVV MIRGGRVKDL PGVRYHIIRG 100
VLDTQGVKNR KQRRSKYGAK RPK 123
Length:123
Mass (Da):13,871
Last modified:February 7, 2006 - v1
Checksum:i183E267BBD72B54B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040264 Genomic DNA. Translation: CAJ11216.1.
RefSeqiYP_414646.1. NC_007618.1.

Genome annotation databases

EnsemblBacteriaiCAJ11216; CAJ11216; BAB1_1260.
GeneIDi3788949.
KEGGibmf:BAB1_1260.
PATRICi17845479. VBIBruMel86222_1309.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040264 Genomic DNA. Translation: CAJ11216.1 .
RefSeqi YP_414646.1. NC_007618.1.

3D structure databases

ProteinModelPortali Q2YLZ8.
SMRi Q2YLZ8. Positions 3-123.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 359391.BAB1_1260.

Proteomic databases

PRIDEi Q2YLZ8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ11216 ; CAJ11216 ; BAB1_1260 .
GeneIDi 3788949.
KEGGi bmf:BAB1_1260.
PATRICi 17845479. VBIBruMel86222_1309.

Phylogenomic databases

eggNOGi COG0048.
HOGENOMi HOG000040063.
KOi K02950.
OMAi VARSKYG.
OrthoDBi EOG61ZTNF.

Enzyme and pathway databases

BioCyci BABO359391:GKDV-1282-MONOMER.
BMEL359391:GJOQ-1282-MONOMER.

Miscellaneous databases

PROi Q2YLZ8.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
HAMAPi MF_00403_B. Ribosomal_S12_B.
InterProi IPR012340. NA-bd_OB-fold.
IPR006032. Ribosomal_S12/S23.
IPR005679. Ribosomal_S12_bac.
[Graphical view ]
PANTHERi PTHR11652. PTHR11652. 1 hit.
Pfami PF00164. Ribosom_S12_S23. 1 hit.
[Graphical view ]
PIRSFi PIRSF002133. Ribosomal_S12/S23. 1 hit.
PRINTSi PR01034. RIBOSOMALS12.
SUPFAMi SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00981. rpsL_bact. 1 hit.
PROSITEi PS00055. RIBOSOMAL_S12. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiRS12_BRUA2
AccessioniPrimary (citable) accession number: Q2YLZ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: February 7, 2006
Last modified: May 14, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi