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Q2YLZ8 (RS12_BRUA2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
30S ribosomal protein S12
Gene names
Name:rpsL
Ordered Locus Names:BAB1_1260
OrganismBrucella abortus (strain 2308) [Complete proteome] [HAMAP]
Taxonomic identifier359391 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length123 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

With S4 and S5 plays an important role in translational accuracy By similarity. HAMAP-Rule MF_00403

Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit By similarity. HAMAP-Rule MF_00403

Subunit structure

Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex By similarity.

Sequence similarities

Belongs to the ribosomal protein S12P family.

Ontologies

Keywords
   LigandRNA-binding
rRNA-binding
tRNA-binding
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentsmall ribosomal subunit

Inferred from electronic annotation. Source: InterPro

   Molecular_functionrRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

structural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

tRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 12312330S ribosomal protein S12 HAMAP-Rule MF_00403
PRO_0000226378

Amino acid modifications

Modified residue8913-methylthioaspartic acid By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2YLZ8 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: 183E267BBD72B54B

FASTA12313,871
        10         20         30         40         50         60 
MPTVNQLIRK PRTAPVKRNK VPALQANPQK RGVCTRVYTT TPKKPNSALR KVAKVRLTNG 

        70         80         90        100        110        120 
FEVIGYIPGE GHNLQEHSVV MIRGGRVKDL PGVRYHIIRG VLDTQGVKNR KQRRSKYGAK 


RPK 

« Hide

References

[1]"Whole-genome analyses of speciation events in pathogenic Brucellae."
Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.
Infect. Immun. 73:8353-8361(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 2308.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM040264 Genomic DNA. Translation: CAJ11216.1.
RefSeqYP_414646.1. NC_007618.1.

3D structure databases

ProteinModelPortalQ2YLZ8.
SMRQ2YLZ8. Positions 3-123.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING359391.BAB1_1260.

Proteomic databases

PRIDEQ2YLZ8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ11216; CAJ11216; BAB1_1260.
GeneID3788949.
KEGGbmf:BAB1_1260.
PATRIC17845479. VBIBruMel86222_1309.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0048.
HOGENOMHOG000040063.
KOK02950.
OMAVARSKYG.
OrthoDBEOG61ZTNF.

Enzyme and pathway databases

BioCycBABO359391:GKDV-1282-MONOMER.
BMEL359391:GJOQ-1282-MONOMER.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
HAMAPMF_00403_B. Ribosomal_S12_B.
InterProIPR012340. NA-bd_OB-fold.
IPR006032. Ribosomal_S12/S23.
IPR005679. Ribosomal_S12_bac.
[Graphical view]
PANTHERPTHR11652. PTHR11652. 1 hit.
PfamPF00164. Ribosom_S12_S23. 1 hit.
[Graphical view]
PIRSFPIRSF002133. Ribosomal_S12/S23. 1 hit.
PRINTSPR01034. RIBOSOMALS12.
SUPFAMSSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00981. rpsL_bact. 1 hit.
PROSITEPS00055. RIBOSOMAL_S12. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROQ2YLZ8.

Entry information

Entry nameRS12_BRUA2
AccessionPrimary (citable) accession number: Q2YLZ8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: February 7, 2006
Last modified: May 14, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

Brucella abortus strain 2308

Brucella abortus (strain 2308): entries and gene names