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Q2YLW6

- THIQ_BRUA2

UniProt

Q2YLW6 - THIQ_BRUA2

Protein

Thiamine import ATP-binding protein ThiQ

Gene

thiQ

Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (07 Feb 2006)
      Previous versions | rss
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    Functioni

    Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi37 – 448ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. thiamine-transporting ATPase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. thiamine transport Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Transport

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBABO359391:GKDV-1816-MONOMER.
    BMEL359391:GJOQ-1816-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thiamine import ATP-binding protein ThiQUniRule annotation (EC:3.6.3.-UniRule annotation)
    Gene namesi
    Name:thiQUniRule annotation
    Ordered Locus Names:BAB1_1772
    OrganismiBrucella abortus (strain 2308)
    Taxonomic identifieri359391 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000002719: Chromosome I

    Subcellular locationi

    Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

    GO - Cellular componenti

    1. ATP-binding cassette (ABC) transporter complex Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 241241Thiamine import ATP-binding protein ThiQPRO_0000274434Add
    BLAST

    Interactioni

    Subunit structurei

    The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).UniRule annotation

    Protein-protein interaction databases

    STRINGi359391.BAB1_1772.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2YLW6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini7 – 235229ABC transporterUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. [View classification]UniRule annotation
    Contains 1 ABC transporter domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG3840.
    KOiK02062.
    OMAiRCHRILR.
    OrthoDBiEOG6SNDS1.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR003593. AAA+_ATPase.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR027417. P-loop_NTPase.
    IPR005968. Thiamine_ABC_ThiQ.
    [Graphical view]
    PfamiPF00005. ABC_tran. 1 hit.
    [Graphical view]
    SMARTiSM00382. AAA. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR01277. thiQ. 1 hit.
    PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 1 hit.
    PS51288. THIQ. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2YLW6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTASADIRLS DVRFSYGETA MHFDVTITGG EIAAIVGPSG SGKSTFLNLI    50
    AGFETPQSGI ISINGVDVTH LPLADRPVSM VFQENNLFAH LTVEQNVDLG 100
    RSPNLRLNEE DRKAVASALA RVGLQGKEKR KPEALSGGER QRVAIARVLV 150
    RERPVLLLDE AFASLGPALR HQMLDLVNKL RRETGMTVLM VTHTPEDALH 200
    LDALLIFLDN GKIAAQGPAT EMLSRAGPEA LRHYIGEMRS F 241
    Length:241
    Mass (Da):26,187
    Last modified:February 7, 2006 - v1
    Checksum:i07D827263C8FE98D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM040264 Genomic DNA. Translation: CAJ11728.1.
    RefSeqiYP_415119.1. NC_007618.1.

    Genome annotation databases

    EnsemblBacteriaiCAJ11728; CAJ11728; BAB1_1772.
    GeneIDi3788282.
    KEGGibmf:BAB1_1772.
    PATRICi17846572. VBIBruMel86222_1835.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM040264 Genomic DNA. Translation: CAJ11728.1 .
    RefSeqi YP_415119.1. NC_007618.1.

    3D structure databases

    ProteinModelPortali Q2YLW6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 359391.BAB1_1772.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAJ11728 ; CAJ11728 ; BAB1_1772 .
    GeneIDi 3788282.
    KEGGi bmf:BAB1_1772.
    PATRICi 17846572. VBIBruMel86222_1835.

    Phylogenomic databases

    eggNOGi COG3840.
    KOi K02062.
    OMAi RCHRILR.
    OrthoDBi EOG6SNDS1.

    Enzyme and pathway databases

    BioCyci BABO359391:GKDV-1816-MONOMER.
    BMEL359391:GJOQ-1816-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR003593. AAA+_ATPase.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR027417. P-loop_NTPase.
    IPR005968. Thiamine_ABC_ThiQ.
    [Graphical view ]
    Pfami PF00005. ABC_tran. 1 hit.
    [Graphical view ]
    SMARTi SM00382. AAA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR01277. thiQ. 1 hit.
    PROSITEi PS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 1 hit.
    PS51288. THIQ. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 2308.

    Entry informationi

    Entry nameiTHIQ_BRUA2
    AccessioniPrimary (citable) accession number: Q2YLW6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 6, 2007
    Last sequence update: February 7, 2006
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Brucella abortus strain 2308
      Brucella abortus (strain 2308): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3