Q2YLI4 (ATPD_BRUA2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
ATP synthase subunit delta

Alternative name(s):
ATP synthase F(1) sector subunit delta
F-type ATPase subunit delta
Short name=F-ATPase subunit delta

Gene names

Name:	atpH
Ordered Locus Names:	BAB1_1810

Organism

Brucella abortus (strain 2308) [Complete proteome] [HAMAP]

Taxonomic identifier

359391 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella abortus

Protein attributes

Sequence length	186 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	F1F0 ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F1 containing the extramembraneous catalytic core and F0 containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation By similarity. HAMAP-Rule MF_01416 This protein is part of the stalk that links CF0 to CF1. It either transmits conformational changes from CF0 to CF1 or is implicated in proton conduction By similarity. HAMAP-Rule MF_01416
Subunit structure	F-type ATPases have 2 components, F1 - the catalytic core - and F0 - the membrane proton channel. F1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. F0 has three main subunits: a1, b2 and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F1 is attached to F0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity HAMAP-Rule MF_01416.
Sequence similarities	Belongs to the ATPase delta chain family.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Cellular component	CF(1) Cell inner membrane Cell membrane Membrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	plasma membrane ATP synthesis coupled proton transport Inferred from electronic annotation. Source: HAMAP
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell proton-transporting ATP synthase complex, catalytic core F(1) Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	proton-transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 186	186	ATP synthase subunit delta HAMAP-Rule MF_01416		PRO_0000370909

Sequences

	Sequence		Length	Mass (Da)
	Q2YLI4 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: DA7DD5340AAAAF41	FASTA	186	19,648
	10 20 30 40 50 60 MAETSSLISG VAQRYAGSLF EHALDANSVA SVEKDLGRFE ALLSGSEDLR RLISSPVFSS 70 80 90 100 110 120 EDQLHAIGAI ADKAGIKGLV GNFLRVVAQN RRLFALPGII AAFRQIAAEH RGEISADVVS 130 140 150 160 170 180 AHELTSAQQN ELKATLKGVA GKDVTINVTV DPSILGGLIV KMGSRQIDTS LRTKLSSLKL ALKEVG

References

[1]

"Whole-genome analyses of speciation events in pathogenic Brucellae." Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E. Infect. Immun. 73:8353-8361(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 2308.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM040264 Genomic DNA. Translation: CAJ11766.1.
RefSeq	YP_415156.1. NC_007618.1.
3D structure databases
ProteinModelPortal	Q2YLI4.
ModBase	Search...
Protein-protein interaction databases
STRING	359391.BAB1_1810.
Proteomic databases
PRIDE	Q2YLI4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAJ11766; CAJ11766; BAB1_1810.
GeneID	3788633.
KEGG	bmf:BAB1_1810.
PATRIC	17846654. VBIBruMel86222_1876.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0712.
HOGENOM	HOG000075825.
KO	K02113.
OMA	ARNRRLF.
ProtClustDB	PRK05758.
Enzyme and pathway databases
BioCyc	BMEL359391:GJOQ-1854-MONOMER.
Family and domain databases
Gene3D	1.10.520.20. 1 hit.
HAMAP	MF_01416. ATP_synth_delta_bact.
InterPro	IPR000711. ATPase_F1-cplx_OSCP/dsu. IPR020781. ATPase_F1-cplx_OSCP/dsu_CS. IPR026015. ATPase_OSCP/delta_N. [Graphical view]
PANTHER	PTHR11910. PTHR11910. 1 hit.
Pfam	PF00213. OSCP. 1 hit. [Graphical view]
PRINTS	PR00125. ATPASEDELTA.
SUPFAM	SSF47928. ATPsynt_OSCP. 1 hit.
TIGRFAMs	TIGR01145. ATP_synt_delta. 1 hit.
PROSITE	PS00389. ATPASE_DELTA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATPD_BRUA2

Accession

Primary (citable) accession number: Q2YLI4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 5, 2009
Last sequence update:	February 7, 2006
Last modified:	May 1, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program