SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q2YL69

- NIKE_BRUA2

UniProt

Q2YL69 - NIKE_BRUA2

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Nickel import ATP-binding protein NikE

Gene
nikE, BAB2_0438
Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system By similarity.

Catalytic activityi

ATP + H2O + Ni2+(Out) = ADP + phosphate + Ni2+(In).

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi45 – 528ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. nickel cation binding Source: InterPro
  3. nickel-transporting ATPase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Ion transport, Nickel transport, Transport

Keywords - Ligandi

ATP-binding, Nickel, Nucleotide-binding

Enzyme and pathway databases

BioCyciBABO359391:GKDV-2683-MONOMER.
BMEL359391:GJOQ-2683-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Nickel import ATP-binding protein NikE (EC:3.6.3.24)
Gene namesi
Name:nikE
Ordered Locus Names:BAB2_0438
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719: Chromosome II

Subcellular locationi

GO - Cellular componenti

  1. ATP-binding cassette (ABC) transporter complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 266266Nickel import ATP-binding protein NikEPRO_0000260204Add
BLAST

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (NikD and NikE), two transmembrane proteins (NikB and NikC) and a solute-binding protein (NikA) Reviewed prediction.

Protein-protein interaction databases

STRINGi359391.BAB2_0438.

Structurei

3D structure databases

ProteinModelPortaliQ2YL69.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 252249ABC transporterAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1124.
KOiK10824.
OMAiNPRKTVC.
OrthoDBiEOG6T7N3V.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR015858. ABC_transpr_NikE.
IPR014137. Nickel_NikE.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02769. nickel_nikE. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51248. NIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2YL69-1 [UniParc]FASTAAdd to Basket

« Hide

MSLISADNIV KIYQSHSLVG ASARKTMLHD ISISIGQGET VALLGRSGCG    50
KSTLARLLVG LERPTSGEVR FRGVPLTKLD RSGMKAFRRE VQLIFQDSPG 100
AVNARSSVRA IIGEPLRHLT SLDETRREER IQELLRLVEL PPEIADRLPA 150
QVSGGQLQRI CIARALAVNP KLIILDEAVS NLDIHLQASA LALLTKLQQE 200
GGIAYLFVTH DLRLVQKFAA RCLVMDEGQI VEEIKTADLD SMRHPASRLL 250
REAVLPPLPV RAVETN 266
Length:266
Mass (Da):29,180
Last modified:February 7, 2006 - v1
Checksum:iCBC0D12AA2731DFB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040265 Genomic DNA. Translation: CAJ12604.1.
RefSeqiYP_418633.1. NC_007624.1.

Genome annotation databases

EnsemblBacteriaiCAJ12604; CAJ12604; BAB2_0438.
GeneIDi3827147.
KEGGibmf:BAB2_0438.
PATRICi17848412. VBIBruMel86222_2733.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040265 Genomic DNA. Translation: CAJ12604.1 .
RefSeqi YP_418633.1. NC_007624.1.

3D structure databases

ProteinModelPortali Q2YL69.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 359391.BAB2_0438.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ12604 ; CAJ12604 ; BAB2_0438 .
GeneIDi 3827147.
KEGGi bmf:BAB2_0438.
PATRICi 17848412. VBIBruMel86222_2733.

Phylogenomic databases

eggNOGi COG1124.
KOi K10824.
OMAi NPRKTVC.
OrthoDBi EOG6T7N3V.

Enzyme and pathway databases

BioCyci BABO359391:GKDV-2683-MONOMER.
BMEL359391:GJOQ-2683-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
InterProi IPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR015858. ABC_transpr_NikE.
IPR014137. Nickel_NikE.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF00005. ABC_tran. 1 hit.
[Graphical view ]
SMARTi SM00382. AAA. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR02769. nickel_nikE. 1 hit.
PROSITEi PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51248. NIKE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiNIKE_BRUA2
AccessioniPrimary (citable) accession number: Q2YL69
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: February 7, 2006
Last modified: July 9, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi