Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Brucella abortus (strain 2308)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Exonuclease, Hydrolase, Nuclease

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII large subunitUniRule annotation
Short name:
Exonuclease VII large subunitUniRule annotation
Gene namesi
Name:xseAUniRule annotation
Ordered Locus Names:BAB2_0475
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000002719 Componenti: Chromosome II

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002736491 – 511Exodeoxyribonuclease 7 large subunitAdd BLAST511

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the XseA family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000229266.
KOiK03601.
OMAiPFMPKVI.

Family and domain databases

CDDicd04489. ExoVII_LU_OBF. 1 hit.
HAMAPiMF_00378. Exonuc_7_L. 1 hit.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2YL15-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASDSSFPGA SSNVAEYSVS EISGALKRTV EDTFGHVRVR GEISGYRGPH
60 70 80 90 100
SSGHAYFALK DDRARLEAVI WRGSMSRLRF RPEEGMEVIA TGKLTTYPGS
110 120 130 140 150
SKYQIVIEQM EPAGAGALMA LLEERKQRLA AEGLFDPTLK QLLPFMPRVI
160 170 180 190 200
GVVTSPTGAV IRDIIHRISD RYPLRVIVWP VRVQGDTCGP EVATAVNGFN
210 220 230 240 250
TLPDDGPIPR PDVLIVARGG GSLEDLWGFN DEIVVRAVAA SHIPVISAVG
260 270 280 290 300
HETDWTLIDL AADMRAPTPT GAAEMAVPVK ADLQASLASQ SARLSSAMSR
310 320 330 340 350
FFDQKRQAHR AAARAMPSAD QLLALPRRRF DEAASRLTRA LFVNTQKKRV
360 370 380 390 400
HFDGHARQLS PRLLQRRLVE LERGVTMLGQ RLPRALEAFL RERRTAFTHR
410 420 430 440 450
ANRLSPEPIL RRTRLTGSTL EQLDRRRDQA VRLLIERVKR RSQELDRLMR
460 470 480 490 500
TLSYESVLER GFAVVFDAQG KPVKQAAAVS PGDALSVRFR DGDVGVVARA
510
GLTIPDPTKG Q
Length:511
Mass (Da):56,363
Last modified:February 7, 2006 - v1
Checksum:i6765E8983A45DB42
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040265 Genomic DNA. Translation: CAJ12641.1.
RefSeqiWP_002968954.1. NZ_KN046823.1.

Genome annotation databases

EnsemblBacteriaiCAJ12641; CAJ12641; BAB2_0475.
GeneIDi3827916.
KEGGibmf:BAB2_0475.
PATRICi17848488. VBIBruMel86222_2771.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040265 Genomic DNA. Translation: CAJ12641.1.
RefSeqiWP_002968954.1. NZ_KN046823.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ12641; CAJ12641; BAB2_0475.
GeneIDi3827916.
KEGGibmf:BAB2_0475.
PATRICi17848488. VBIBruMel86222_2771.

Phylogenomic databases

HOGENOMiHOG000229266.
KOiK03601.
OMAiPFMPKVI.

Miscellaneous databases

PROiQ2YL15.

Family and domain databases

CDDicd04489. ExoVII_LU_OBF. 1 hit.
HAMAPiMF_00378. Exonuc_7_L. 1 hit.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiEX7L_BRUA2
AccessioniPrimary (citable) accession number: Q2YL15
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: February 7, 2006
Last modified: November 2, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.