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Protein

Putative ATP-binding protein BAB2_0493

Gene

BAB2_0493

Organism
Brucella abortus (strain 2308)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Probably part of an ABC transporter complex. Probably responsible for energy coupling to the transport system (Probable).Curated

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi36 – 438ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATPase activity Source: InterPro
  2. ATP binding Source: UniProtKB-KW
  3. hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBABO359391:GKDV-2739-MONOMER.
BMEL359391:GJOQ-2739-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative ATP-binding protein BAB2_0493 (EC:3.6.3.-)
Gene namesi
Ordered Locus Names:BAB2_0493
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719 Componenti: Chromosome II

Subcellular locationi

GO - Cellular componenti

  1. ATP-binding cassette (ABC) transporter complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 350350Putative ATP-binding protein BAB2_0493PRO_0000281199Add
BLAST

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (BAB2_0493), two transmembrane proteins (BAB2_0490) and a solute-binding protein (BAB2_0491).Curated

Protein-protein interaction databases

STRINGi359391.BAB2_0493.

Structurei

3D structure databases

ProteinModelPortaliQ2YKZ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 234231ABC transporterPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated
Contains 1 ABC transporter domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG3839.
KOiK10112.
OMAiNIDDGER.
OrthoDBiEOG6T7N3V.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR008995. Mo/tungstate-bd_C_term_dom.
IPR012340. NA-bd_OB-fold.
IPR027417. P-loop_NTPase.
IPR013611. Transp-assoc_OB_typ2.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
PF08402. TOBE_2. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF50331. SSF50331. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2YKZ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKEVSLRGIS KTFGQLTVLD RIDLEIHSGE FLVLVGPSGC GKSTLLRMVA
60 70 80 90 100
GLEPISGGDL VIGGERANEL PPQKRNIAMV FQSYALFPHM TARENIGFGP
110 120 130 140 150
RIRGEKAAET AAKVDHAASI LNLHSYLDRY PRQLSGGQRQ RVAMGRAIVR
160 170 180 190 200
EPSVFLFDEP LSNLDAQLRV QMRTEIKALH QRLKSTVIYV THDQIEAMTM
210 220 230 240 250
ADRIVVMNQG KIQQIGAPLD LYDRPANKFV AGFIGSPSMS FIPGTVADGF
260 270 280 290 300
FCTGEGEKIA VSAAAKGARA AEAGIRPENF VIAREGAGLT LVVEVIEPTG
310 320 330 340 350
PETHIYGRIA GEPVRAVFRE RIQLAPGEQV PVTAGSEHIH LFDKESGLPL
Length:350
Mass (Da):37,984
Last modified:February 7, 2006 - v1
Checksum:iA43F81FE5C1E44D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040265 Genomic DNA. Translation: CAJ12659.1.
RefSeqiYP_418687.1. NC_007624.1.

Genome annotation databases

EnsemblBacteriaiCAJ12659; CAJ12659; BAB2_0493.
KEGGibmf:BAB2_0493.
PATRICi17848526. VBIBruMel86222_2790.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040265 Genomic DNA. Translation: CAJ12659.1.
RefSeqiYP_418687.1. NC_007624.1.

3D structure databases

ProteinModelPortaliQ2YKZ7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi359391.BAB2_0493.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ12659; CAJ12659; BAB2_0493.
KEGGibmf:BAB2_0493.
PATRICi17848526. VBIBruMel86222_2790.

Phylogenomic databases

eggNOGiCOG3839.
KOiK10112.
OMAiNIDDGER.
OrthoDBiEOG6T7N3V.

Enzyme and pathway databases

BioCyciBABO359391:GKDV-2739-MONOMER.
BMEL359391:GJOQ-2739-MONOMER.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR008995. Mo/tungstate-bd_C_term_dom.
IPR012340. NA-bd_OB-fold.
IPR027417. P-loop_NTPase.
IPR013611. Transp-assoc_OB_typ2.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
PF08402. TOBE_2. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF50331. SSF50331. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiY2993_BRUA2
AccessioniPrimary (citable) accession number: Q2YKZ7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: February 7, 2006
Last modified: April 1, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.