Q2YKR7 (UGPE_BRUA2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
sn-glycerol-3-phosphate transport system permease protein UgpE

Gene names

Name:	ugpE
Ordered Locus Names:	BAB2_0583

Organism

Brucella abortus (strain 2308) [Complete proteome] [HAMAP]

Taxonomic identifier

359391 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella abortus

Protein attributes

Sequence length	282 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Probably responsible for the translocation of the substrate across the membrane By similarity.
Subunit structure	The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB) Probable.
Subcellular location	Cell inner membrane; Multi-pass membrane protein Probable.
Sequence similarities	Belongs to the binding-protein-dependent transport system permease family. Contains 1 ABC transmembrane type-1 domain.

Ontologies

Keywords
Biological process	Sugar transport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbohydrate transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 282	282	sn-glycerol-3-phosphate transport system permease protein UgpE		PRO_0000290138
Regions
	Transmembrane	14 – 34	21	Helical; Potential
	Transmembrane	86 – 106	21	Helical; Potential
	Transmembrane	112 – 132	21	Helical; Potential
	Transmembrane	146 – 168	23	Helical; Potential
	Transmembrane	201 – 221	21	Helical; Potential
	Transmembrane	248 – 268	21	Helical; Potential
	Domain	78 – 269	192	ABC transmembrane type-1

Sequences

	Sequence		Length	Mass (Da)
	Q2YKR7 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 14D8EC2256561765	FASTA	282	32,052
	10 20 30 40 50 60 MIEQRPVSNL IGHLILILGI IIVAFPIYYT FVASSMTSTQ IIRPPISLLP GDHLVENYRE 70 80 90 100 110 120 AIFGGVERVV GVSLERLLWN SFVVAMAIAV GKIIISFMSA FAIVFFRFPM RMFFFWMIFI 130 140 150 160 170 180 TLMLPVEVRI LPTYKVIVDL GMIDTYAGLT LPLMASATAT FLFRQFFLTI PGELVEAARI 190 200 210 220 230 240 DNAGPFRFMR DILLPLSKTN IAALFVILFI YGWTQYLWPL LVTNDAKMNT IIIGLRRMVD 250 260 270 280 WADASTPWNY VMVTAILAII PLILVVVLMQ RWFVKGLVET EK

References

[1]

"Whole-genome analyses of speciation events in pathogenic Brucellae." Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E. Infect. Immun. 73:8353-8361(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 2308.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM040265 Genomic DNA. Translation: CAJ12749.1.
RefSeq	YP_418767.1. NC_007624.1.
3D structure databases
ProteinModelPortal	Q2YKR7.
ModBase	Search...
Protein-protein interaction databases
STRING	359391.BAB2_0583.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAJ12749; CAJ12749; BAB2_0583.
GeneID	3827696.
KEGG	bmf:BAB2_0583.
PATRIC	17848703. VBIBruMel86222_2877.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0395.
HOGENOM	HOG000220524.
KO	K05815.
OMA	TDASTPW.
ProtClustDB	CLSK881849.
Enzyme and pathway databases
BioCyc	BMEL359391:GJOQ-2831-MONOMER.
Family and domain databases
InterPro	IPR000515. BPD_transp. [Graphical view]
Pfam	PF00528. BPD_transp_1. 1 hit. [Graphical view]
PROSITE	PS50928. ABC_TM1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UGPE_BRUA2

Accession

Primary (citable) accession number: Q2YKR7

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 12, 2007
Last sequence update:	February 7, 2006
Last modified:	May 1, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program