Q2YKL0 (Q2YKL0_BRUA2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Topoisomerase IV, subunit B:DNA gyrase, subunit B:DNA topoisomerase II:DNA gyrase, subunit B, C-terminal:ATP-binding region, ... EMBL CAJ12815.1
EC=5.99.1.3 EMBL CAJ12815.1

Gene names

Ordered Locus Names:

BAB2_0649

Organism

Brucella abortus (strain 2308) [Complete proteome] [HAMAP]

Taxonomic identifier

359391 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	699 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the type II topoisomerase family. RuleBase RU000380

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000380 SAAS SAAS002288 EMBL CAJ12815.1 Nucleotide-binding
Molecular function	Isomerase Topoisomerase SAAS SAAS002288 RuleBase RU000380
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA topological change Inferred from electronic annotation. Source: InterPro
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA topoisomerase (ATP-hydrolyzing) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2YKL0 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 737437CCACAA9B13	FASTA	699	77,208
	10 20 30 40 50 60 MDDSNDLFSR VVNNARERQM ERQTGENTVA QPVVQPAPSA PKPVPAAAKA PPAASGGDDY 70 80 90 100 110 120 NASSIRVLEG LEPVRLRPGM YIGGTDEKAL HHLFAEVIDN SMDEAVAGHA NFIEVTVDKE 130 140 150 160 170 180 GFVTVSDNGR GIPVDEHPQV PGKSTLEVIM TKLHAGGKFD GKAYETSGGL HGVGVSVVNA 190 200 210 220 230 240 LSDVLEVEVA RNRRLYRQCF SRGIPQGGLE ELGEVHNRRG TRVRFHPDPE IFGKNAHFDP 250 260 270 280 290 300 HRLYRMARSK AYLFGGVEIR WNCDPSLLDP KKETPEKAVF HFPGGLKDYL EASLGKEHQV 310 320 330 340 350 360 TREVFAGRTE KQGGHGAVEW AVAWFGGDGF VHSYCNTIPT GDGGTHEAGL RIALTRGLKA 370 380 390 400 410 420 YAELTNNKRA SIITTDDVMV SAAGMLSVFI REPEFVGQTK DKLATVEAQR LVENAIRDPF 430 440 450 460 470 480 DHWLAASPQE ASRLLEWVID RADERLRRRQ EKETVRKSAT RKLRLPGKLA DCTQNAAAGA 490 500 510 520 530 540 ELFIVEGDSA GGSAKQARNR ANQAILPLRG KILNVASAGR EKLTANQQIA DLVQALGCGT 550 560 570 580 590 600 RKNYREDDLR YDRVIVMTDA DVDGAHIASL LITFFYQEMP ELIRNGHLYL AVPPLYRLSQ 610 620 630 640 650 660 GGKTAYARDD AHKEELLRTV FTGRGKIEIG RFKGLGEMRA DQLKETTMDP AKRTLLRVQV 670 680 690 DEEYGDETRN TVDDLMGTKP EARFRFIQDR AAFVEELDI

References

[1]

"Whole-genome analyses of speciation events in pathogenic Brucellae." Microbial Genomics Group, Lawrence Livermore National Laboratory, and the Genome Analysis Group, Oak Ridge National Laboratory Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E. Infect. Immun. 73:8353-8361(2005) [PubMed: 16299333] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 2308.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM040265 Genomic DNA. Translation: CAJ12815.1.
RefSeq	YP_418824.1. NC_007624.1.
3D structure databases
ProteinModelPortal	Q2YKL0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2YKL0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3827967.
GenomeReviews	Gene locus BAB2_0649 in contig AM040265_GR.
KEGG	bmf:BAB2_0649.
PATRIC	17848841. VBIBruMel86222_2943.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0187.
HOGENOM	HBG304889.
OMA	QARDKEF.
ProtClustDB	PRK05559.
Family and domain databases
InterPro	IPR003594. ATPase-like_ATP-bd. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR001241. Topo_IIA. IPR013759. Topo_IIA_B/N_ab. IPR002288. Topo_IIA_B_C. IPR013506. Topo_IIA_bsu_dom2. IPR013760. Topo_IIA_cen. IPR018522. TopoIIA_CS. IPR005737. TopoIV_B_Gneg. IPR006171. Toprim_domain. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit. G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 1 hit.
KO	K02622.
Pfam	PF00204. DNA_gyraseB. 1 hit. PF00986. DNA_gyraseB_C. 1 hit. PF02518. HATPase_c. 1 hit. PF01751. Toprim. 1 hit. [Graphical view]
PRINTS	PR00418. TPI2FAMILY.
SMART	SM00387. HATPase_c. 1 hit. SM00433. TOP2c. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMs	TIGR01055. ParE_Gneg. 1 hit.
PROSITE	PS00177. TOPOISOMERASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2YKL0_BRUA2

Accession

Primary (citable) accession number: Q2YKL0

Entry history

Integrated into UniProtKB/TrEMBL:	February 7, 2006
Last sequence update:	February 7, 2006
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)