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Protein

Bacterioferritin

Gene

bfr

Organism
Brucella abortus (strain 2308)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Iron-storage protein, whose ferroxidase center binds Fe2+ ions, oxidizes them by dioxygen to Fe3+, and participates in the subsequent Fe3+ oxide mineral core formation within the central cavity of the protein complex.UniRule annotation

Catalytic activityi

4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi18 – 181IronCombined sources
Metal bindingi51 – 511IronCombined sources
Metal bindingi54 – 541Iron; via pros nitrogenCombined sources
Metal bindingi127 – 1271IronCombined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Iron storageUniRule annotation

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

BioCyciBABO359391:GKDV-2926-MONOMER.
BMEL359391:GJOQ-2926-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
BacterioferritinUniRule annotation (EC:1.16.3.1UniRule annotation)
Gene namesi
Name:bfrImported
Ordered Locus Names:BAB2_0675Imported
OrganismiBrucella abortus (strain 2308)Imported
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000002719 Componenti: Chromosome II

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ2YKI4.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3FVBX-ray1.81A/B1-161[»]
ProteinModelPortaliQ2YKI4.
SMRiQ2YKI4. Positions 1-160.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ2YKI4.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 145145Ferritin-like diironInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the bacterioferritin family.UniRule annotation
Contains 1 ferritin-like diiron domain.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000262383.
KOiK03594.
OMAiEMKHADQ.

Family and domain databases

CDDicd00907. Bacterioferritin. 1 hit.
Gene3Di1.20.1260.10. 1 hit.
InterProiIPR002024. Bacterioferritin.
IPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR008331. Ferritin_DPS_dom.
[Graphical view]
PfamiPF00210. Ferritin. 1 hit.
[Graphical view]
PIRSFiPIRSF002560. Bacterioferritin. 1 hit.
PRINTSiPR00601. BACFERRITIN.
SUPFAMiSSF47240. SSF47240. 1 hit.
TIGRFAMsiTIGR00754. bfr. 1 hit.
PROSITEiPS00549. BACTERIOFERRITIN. 1 hit.
PS50905. FERRITIN_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2YKI4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGEPKVIER LNEALFLELG AVNQYWLHYR LLNDWGYTRL AKKEREESIE
60 70 80 90 100
EMHHADKLID RIIFLEGFPN LQTVSPLRIG QNVKEVLEAD LKGEYDARAS
110 120 130 140 150
YKESREICDK LGDYVSKQLF DELLADEEGH IDFLETQLDL LAKIGGERYG
160
QLNAAPADEA E
Length:161
Mass (Da):18,568
Last modified:February 7, 2006 - v1
Checksum:iCBD0A44BE843DDCC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040265 Genomic DNA. Translation: CAJ12841.1.
RefSeqiWP_002966069.1. NZ_KN046823.1.

Genome annotation databases

EnsemblBacteriaiCAJ12841; CAJ12841; BAB2_0675.
GeneIDi3828133.
KEGGibmf:BAB2_0675.
PATRICi17848900. VBIBruMel86222_2971.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040265 Genomic DNA. Translation: CAJ12841.1.
RefSeqiWP_002966069.1. NZ_KN046823.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3FVBX-ray1.81A/B1-161[»]
ProteinModelPortaliQ2YKI4.
SMRiQ2YKI4. Positions 1-160.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ2YKI4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ12841; CAJ12841; BAB2_0675.
GeneIDi3828133.
KEGGibmf:BAB2_0675.
PATRICi17848900. VBIBruMel86222_2971.

Phylogenomic databases

HOGENOMiHOG000262383.
KOiK03594.
OMAiEMKHADQ.

Enzyme and pathway databases

BioCyciBABO359391:GKDV-2926-MONOMER.
BMEL359391:GJOQ-2926-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ2YKI4.

Family and domain databases

CDDicd00907. Bacterioferritin. 1 hit.
Gene3Di1.20.1260.10. 1 hit.
InterProiIPR002024. Bacterioferritin.
IPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR008331. Ferritin_DPS_dom.
[Graphical view]
PfamiPF00210. Ferritin. 1 hit.
[Graphical view]
PIRSFiPIRSF002560. Bacterioferritin. 1 hit.
PRINTSiPR00601. BACFERRITIN.
SUPFAMiSSF47240. SSF47240. 1 hit.
TIGRFAMsiTIGR00754. bfr. 1 hit.
PROSITEiPS00549. BACTERIOFERRITIN. 1 hit.
PS50905. FERRITIN_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ2YKI4_BRUA2
AccessioniPrimary (citable) accession number: Q2YKI4
Entry historyi
Integrated into UniProtKB/TrEMBL: February 7, 2006
Last sequence update: February 7, 2006
Last modified: September 7, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.