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Q2YKB2

- META_BRUA2

UniProt

Q2YKB2 - META_BRUA2

Protein

Homoserine O-succinyltransferase

Gene

metA

Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (07 Feb 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Succinyl-CoA + L-homoserine = CoA + O-succinyl-L-homoserine.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei142 – 1421UniRule annotation

    GO - Molecular functioni

    1. homoserine O-succinyltransferase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Keywords - Biological processi

    Amino-acid biosynthesis, Methionine biosynthesis

    Enzyme and pathway databases

    BioCyciBABO359391:GKDV-3003-MONOMER.
    BMEL359391:GJOQ-3003-MONOMER.
    UniPathwayiUPA00051; UER00075.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Homoserine O-succinyltransferaseUniRule annotation (EC:2.3.1.46UniRule annotation)
    Alternative name(s):
    Homoserine O-transsuccinylaseUniRule annotation
    Short name:
    HTSUniRule annotation
    Gene namesi
    Name:metAUniRule annotation
    Ordered Locus Names:BAB2_0751
    OrganismiBrucella abortus (strain 2308)
    Taxonomic identifieri359391 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000002719: Chromosome II

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 306306Homoserine O-succinyltransferasePRO_1000021803Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi359391.BAB2_0751.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2YKB2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the HTS family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1897.
    HOGENOMiHOG000115049.
    KOiK00651.
    OMAiFEDVIYW.
    OrthoDBiEOG61P6ST.

    Family and domain databases

    Gene3Di3.40.50.880. 1 hit.
    HAMAPiMF_00295. Homoser_O_succinyltr.
    InterProiIPR029062. Class_I_gatase-like.
    IPR005697. Homserine_suc_trans.
    [Graphical view]
    PANTHERiPTHR20919. PTHR20919. 1 hit.
    PfamiPF04204. HTS. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000450. H_ser_succinyltr. 1 hit.
    ProDomiPD037892. Homserine_suc_trans. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF52317. SSF52317. 1 hit.
    TIGRFAMsiTIGR01001. metA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q2YKB2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPIKIPDDLP ATSVLEAEGV MVMREADAVR QDIRPLRIGL LNLMPNKVTT    50
    ETQIARLLGA TPLQVELTLV RMTNHVARHT PADHMLSFYC PWEEVNDQRF 100
    DGFVITGAPV ERLPFEEVTY WDEMRRVFDW TQSHVHRTLN ICWAAQAAVY 150
    HFHGMKKYDL PAKASGVFRQ RSLVPASPYL RGFSDDFAIP VSRWTEVRKS 200
    DIPADSGLKV LVDSTETGLC LLDDPRHRSL HMFNHVEYDT TSLADEYFRD 250
    IQVQPEAKVP VNYFPGDDAK RPPENRWRSH AHLLFGNWIN EMYQSTPYDI 300
    ERIGKV 306
    Length:306
    Mass (Da):35,245
    Last modified:February 7, 2006 - v1
    Checksum:iE942A97E01C13E47
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM040265 Genomic DNA. Translation: CAJ12917.1.
    RefSeqiYP_418922.1. NC_007624.1.

    Genome annotation databases

    EnsemblBacteriaiCAJ12917; CAJ12917; BAB2_0751.
    GeneIDi3827179.
    KEGGibmf:BAB2_0751.
    PATRICi17849050. VBIBruMel86222_3045.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM040265 Genomic DNA. Translation: CAJ12917.1 .
    RefSeqi YP_418922.1. NC_007624.1.

    3D structure databases

    ProteinModelPortali Q2YKB2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 359391.BAB2_0751.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAJ12917 ; CAJ12917 ; BAB2_0751 .
    GeneIDi 3827179.
    KEGGi bmf:BAB2_0751.
    PATRICi 17849050. VBIBruMel86222_3045.

    Phylogenomic databases

    eggNOGi COG1897.
    HOGENOMi HOG000115049.
    KOi K00651.
    OMAi FEDVIYW.
    OrthoDBi EOG61P6ST.

    Enzyme and pathway databases

    UniPathwayi UPA00051 ; UER00075 .
    BioCyci BABO359391:GKDV-3003-MONOMER.
    BMEL359391:GJOQ-3003-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.880. 1 hit.
    HAMAPi MF_00295. Homoser_O_succinyltr.
    InterProi IPR029062. Class_I_gatase-like.
    IPR005697. Homserine_suc_trans.
    [Graphical view ]
    PANTHERi PTHR20919. PTHR20919. 1 hit.
    Pfami PF04204. HTS. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000450. H_ser_succinyltr. 1 hit.
    ProDomi PD037892. Homserine_suc_trans. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF52317. SSF52317. 1 hit.
    TIGRFAMsi TIGR01001. metA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 2308.

    Entry informationi

    Entry nameiMETA_BRUA2
    AccessioniPrimary (citable) accession number: Q2YKB2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: February 7, 2006
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Brucella abortus strain 2308
      Brucella abortus (strain 2308): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3