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Q2YK17

- GLSA_BRUA2

UniProt

Q2YK17 - GLSA_BRUA2

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Protein

Glutaminase

Gene

glsA

Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei67 – 671SubstrateUniRule annotation
Binding sitei118 – 1181SubstrateUniRule annotation
Binding sitei162 – 1621SubstrateUniRule annotation
Binding sitei169 – 1691SubstrateUniRule annotation
Binding sitei193 – 1931SubstrateUniRule annotation
Binding sitei245 – 2451SubstrateUniRule annotation
Binding sitei263 – 2631Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciBABO359391:GKDV-3115-MONOMER.
BMEL359391:GJOQ-3115-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:BAB2_0863
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719: Chromosome II

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 317317GlutaminasePRO_1000048327Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi359391.BAB2_0863.

Structurei

3D structure databases

ProteinModelPortaliQ2YK17.
SMRiQ2YK17. Positions 5-309.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiQCSVGVT.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2YK17-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSSSSDAIKA ALEKGRAAGL SATGGKNADY IPFLASVPSD LFGLAVVTAD
60 70 80 90 100
GQTFKTGDAD IAFAIESISK VFTLALVMEE IGPDSVREKV GADPTGLPFN
110 120 130 140 150
SVIALELHNG KSLSPLVNAG AIATASLVPG DTADARWNNI LECQCGFAGR
160 170 180 190 200
RLKLSNEVNQ SEQTTNFHNR AIAWLLYSAG TCYSDPMEAV DIYTRQCSTL
210 220 230 240 250
VTATDLATMG ATLAAGGVNP ISGKRMVSAG NVAPILVEMT MEGLYTALGD
260 270 280 290 300
WAYTVGLPGK SGVGGGIMAV VPGELAIAAF SPPLDPAGNS VKAMAAVAAV
310
ADSLGHNLYT TRGKVSS
Length:317
Mass (Da):32,463
Last modified:February 7, 2006 - v1
Checksum:iA5ED37D230E862BD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040265 Genomic DNA. Translation: CAJ13029.1.
RefSeqiYP_419017.1. NC_007624.1.

Genome annotation databases

EnsemblBacteriaiCAJ13029; CAJ13029; BAB2_0863.
GeneIDi3827366.
KEGGibmf:BAB2_0863.
PATRICi17849272. VBIBruMel86222_3155.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040265 Genomic DNA. Translation: CAJ13029.1 .
RefSeqi YP_419017.1. NC_007624.1.

3D structure databases

ProteinModelPortali Q2YK17.
SMRi Q2YK17. Positions 5-309.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 359391.BAB2_0863.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ13029 ; CAJ13029 ; BAB2_0863 .
GeneIDi 3827366.
KEGGi bmf:BAB2_0863.
PATRICi 17849272. VBIBruMel86222_3155.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi QCSVGVT.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci BABO359391:GKDV-3115-MONOMER.
BMEL359391:GJOQ-3115-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiGLSA_BRUA2
AccessioniPrimary (citable) accession number: Q2YK17
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 7, 2006
Last modified: October 1, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3