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Q2YJR0

- ARGB_BRUA2

UniProt

Q2YJR0 - ARGB_BRUA2

Protein

Acetylglutamate kinase

Gene

argB

Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (07 Feb 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei32 – 321Transition state stabilizerUniRule annotation
    Binding sitei89 – 891SubstrateUniRule annotation
    Binding sitei194 – 1941SubstrateUniRule annotation
    Sitei254 – 2541Transition state stabilizerUniRule annotation

    GO - Molecular functioni

    1. acetylglutamate kinase activity Source: UniProtKB-HAMAP
    2. ATP binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. arginine biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Amino-acid biosynthesis, Arginine biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBABO359391:GKDV-3242-MONOMER.
    BMEL359391:GJOQ-3242-MONOMER.
    UniPathwayiUPA00068; UER00107.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acetylglutamate kinaseUniRule annotation (EC:2.7.2.8UniRule annotation)
    Alternative name(s):
    N-acetyl-L-glutamate 5-phosphotransferaseUniRule annotation
    NAG kinaseUniRule annotation
    Short name:
    AGKUniRule annotation
    Gene namesi
    Name:argBUniRule annotation
    Ordered Locus Names:BAB2_0988
    OrganismiBrucella abortus (strain 2308)
    Taxonomic identifieri359391 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000002719: Chromosome II

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 296296Acetylglutamate kinasePRO_0000264685Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi359391.BAB2_0988.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2YJR0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni67 – 682Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the acetylglutamate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0548.
    HOGENOMiHOG000233259.
    KOiK00930.
    OMAiPGVLDKN.
    OrthoDBiEOG6T1WVF.

    Family and domain databases

    Gene3Di3.40.1160.10. 1 hit.
    HAMAPiMF_00082_B. ArgB_B.
    InterProiIPR004662. AcgluKinase.
    IPR001048. Asp/Glu/Uridylate_kinase.
    [Graphical view]
    PfamiPF00696. AA_kinase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000728. NAGK. 1 hit.
    SUPFAMiSSF53633. SSF53633. 1 hit.
    TIGRFAMsiTIGR00761. argB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q2YJR0-1 [UniParc]FASTAAdd to Basket

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    MTTLENPEMQ AQLLSAALPY MQRYENKHVV VKYGGHAMGN PELGKAFARD    50
    VALLKQSGVN PIVVHGGGPQ IQAMLTKLGI ESRFEGGLRV TDEKTVEVVE 100
    MVLAGSINKE IVALINAEGE WAIGLCGKDG NMVFAQKAHK TVIDPDSNIE 150
    KVLDLGFVGE PAEVDRTLLD LLARSEMIPV IAPVAPGRDG HTYNINADTF 200
    AGAIAGALAA TRLLFLTNVP GVLDKDKKLI KELSVADAQA LIRDGTISGG 250
    MIPKVETCID AIRRGVEGVV ILNGKTPHSV LLELFTEHGA GTLIVP 296
    Length:296
    Mass (Da):31,498
    Last modified:February 7, 2006 - v1
    Checksum:i5875CCF2D28AE18E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM040265 Genomic DNA. Translation: CAJ13154.1.
    RefSeqiYP_419124.1. NC_007624.1.

    Genome annotation databases

    EnsemblBacteriaiCAJ13154; CAJ13154; BAB2_0988.
    GeneIDi3827318.
    KEGGibmf:BAB2_0988.
    PATRICi17849536. VBIBruMel86222_3285.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM040265 Genomic DNA. Translation: CAJ13154.1 .
    RefSeqi YP_419124.1. NC_007624.1.

    3D structure databases

    ProteinModelPortali Q2YJR0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 359391.BAB2_0988.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAJ13154 ; CAJ13154 ; BAB2_0988 .
    GeneIDi 3827318.
    KEGGi bmf:BAB2_0988.
    PATRICi 17849536. VBIBruMel86222_3285.

    Phylogenomic databases

    eggNOGi COG0548.
    HOGENOMi HOG000233259.
    KOi K00930.
    OMAi PGVLDKN.
    OrthoDBi EOG6T1WVF.

    Enzyme and pathway databases

    UniPathwayi UPA00068 ; UER00107 .
    BioCyci BABO359391:GKDV-3242-MONOMER.
    BMEL359391:GJOQ-3242-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1160.10. 1 hit.
    HAMAPi MF_00082_B. ArgB_B.
    InterProi IPR004662. AcgluKinase.
    IPR001048. Asp/Glu/Uridylate_kinase.
    [Graphical view ]
    Pfami PF00696. AA_kinase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000728. NAGK. 1 hit.
    SUPFAMi SSF53633. SSF53633. 1 hit.
    TIGRFAMsi TIGR00761. argB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 2308.

    Entry informationi

    Entry nameiARGB_BRUA2
    AccessioniPrimary (citable) accession number: Q2YJR0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 12, 2006
    Last sequence update: February 7, 2006
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Brucella abortus strain 2308
      Brucella abortus (strain 2308): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3