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Q2YJ83 (YP57_BRUA2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Type IV secretion system putative outer membrane lipoprotein BAB2_0057
Gene names
Ordered Locus Names:BAB2_0057
OrganismBrucella abortus (strain 2308) [Complete proteome] [HAMAP]
Taxonomic identifier359391 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length172 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existencePredicted

General annotation (Comments)

Function

The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice. This protein is essential for pathogenesis in mice but is not required for intracellular survival. Ref.1

Subcellular location

Cell outer membrane; Lipid-anchor Potential.

Miscellaneous

Transcription is turned on at the beginning of the stationary phase of vegetative growth.

Sequence similarities

Contains 1 OmpA-like domain.

Ontologies

Keywords
   Biological processVirulence
   Cellular componentCell outer membrane
Membrane
   DomainSignal
   PTMLipoprotein
Palmitate
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpathogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcell outer membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1515 Potential
Chain16 – 172157Type IV secretion system putative outer membrane lipoprotein BAB2_0057
PRO_0000291445

Regions

Domain58 – 172115OmpA-like

Amino acid modifications

Lipidation161N-palmitoyl cysteine Potential
Lipidation161S-diacylglycerol cysteine Potential

Sequences

Sequence LengthMass (Da)Tools
Q2YJ83 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: BEE06DB62310185E

FASTA17219,028
        10         20         30         40         50         60 
MRTLVMVACA VSLAACSSPP KPPTVSGRHR IPINSPAAQE ELRLQVFPQE PTAQATMWPA 

        70         80         90        100        110        120 
RPPKQTVNVY FPQDVTVFRP TSAQINQLHT LLWPVPKHIN VRGLTDNNCP PPGDTQVARV 

       130        140        150        160        170 
RALAIYNWLI NQGVPASRIT ISYAPVKDYA SNAPLSPGRV LNRRVDIEIL RK 

« Hide

References

« Hide 'large scale' references
[1]"A homologue of an operon required for DNA transfer in Agrobacterium is required in Brucella abortus for virulence and intracellular multiplication."
Sieira R., Comerci D.J., Sanchez D.O., Ugalde R.A.
J. Bacteriol. 182:4849-4855(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], TRANSCRIPTION, FUNCTION.
[2]"Whole-genome analyses of speciation events in pathogenic Brucellae."
Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.
Infect. Immun. 73:8353-8361(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 2308.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF226278 Genomic DNA. Translation: AAF73905.1.
AM040265 Genomic DNA. Translation: CAJ12223.1.
RefSeqYP_418302.1. NC_007624.1.

3D structure databases

ProteinModelPortalQ2YJ83.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING359391.BAB2_0057.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ12223; CAJ12223; BAB2_0057.
GeneID3827894.
KEGGbmf:BAB2_0057.
PATRIC17847599. VBIBruMel86222_2333.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2885.
HOGENOMHOG000289240.
OMANSQMAVE.
OrthoDBEOG6PP9QB.

Enzyme and pathway databases

BioCycBABO359391:GKDV-2300-MONOMER.
BMEL359391:GJOQ-2300-MONOMER.

Family and domain databases

Gene3D3.30.1330.60. 1 hit.
InterProIPR006665. OmpA/MotB_C.
[Graphical view]
PfamPF00691. OmpA. 1 hit.
[Graphical view]
SUPFAMSSF103088. SSF103088. 1 hit.
PROSITEPS51123. OMPA_2. 1 hit.
PS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYP57_BRUA2
AccessionPrimary (citable) accession number: Q2YJ83
Secondary accession number(s): Q57A25, Q9KIS3
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: February 7, 2006
Last modified: May 14, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella abortus strain 2308

Brucella abortus (strain 2308): entries and gene names