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Protein

Type IV secretion system putative outer membrane lipoprotein BAB2_0057

Gene

BAB2_0057

Organism
Brucella abortus (strain 2308)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice. This protein is essential for pathogenesis in mice but is not required for intracellular survival.1 Publication

Miscellaneous

Transcription is turned on at the beginning of the stationary phase of vegetative growth.

GO - Biological processi

Keywordsi

Biological processVirulence

Names & Taxonomyi

Protein namesi
Recommended name:
Type IV secretion system putative outer membrane lipoprotein BAB2_0057
Gene namesi
Ordered Locus Names:BAB2_0057
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000002719 Componenti: Chromosome II

Subcellular locationi

  • Cell outer membrane Curated; Lipid-anchor PROSITE-ProRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15PROSITE-ProRule annotationAdd BLAST15
ChainiPRO_000029144516 – 172Type IV secretion system putative outer membrane lipoprotein BAB2_0057Add BLAST157

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi16N-palmitoyl cysteinePROSITE-ProRule annotation1
Lipidationi16S-diacylglycerol cysteinePROSITE-ProRule annotation1

Keywords - PTMi

Lipoprotein, Palmitate

Structurei

3D structure databases

ProteinModelPortaliQ2YJ83.
SMRiQ2YJ83.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini58 – 172OmpA-likePROSITE-ProRule annotationAdd BLAST115

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000289240.
OMAiNSQMAVE.

Family and domain databases

Gene3Di3.30.1330.60. 1 hit.
InterProiView protein in InterPro
IPR006665. OmpA-like.
PfamiView protein in Pfam
PF00691. OmpA. 1 hit.
SUPFAMiSSF103088. SSF103088. 1 hit.
PROSITEiView protein in PROSITE
PS51123. OMPA_2. 1 hit.
PS51257. PROKAR_LIPOPROTEIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2YJ83-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTLVMVACA VSLAACSSPP KPPTVSGRHR IPINSPAAQE ELRLQVFPQE
60 70 80 90 100
PTAQATMWPA RPPKQTVNVY FPQDVTVFRP TSAQINQLHT LLWPVPKHIN
110 120 130 140 150
VRGLTDNNCP PPGDTQVARV RALAIYNWLI NQGVPASRIT ISYAPVKDYA
160 170
SNAPLSPGRV LNRRVDIEIL RK
Length:172
Mass (Da):19,028
Last modified:February 7, 2006 - v1
Checksum:iBEE06DB62310185E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF226278 Genomic DNA. Translation: AAF73905.1.
AM040265 Genomic DNA. Translation: CAJ12223.1.
RefSeqiWP_002966521.1. NZ_KN046823.1.

Genome annotation databases

EnsemblBacteriaiCAJ12223; CAJ12223; BAB2_0057.
GeneIDi3827894.
KEGGibmf:BAB2_0057.
PATRICi17847599. VBIBruMel86222_2333.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF226278 Genomic DNA. Translation: AAF73905.1.
AM040265 Genomic DNA. Translation: CAJ12223.1.
RefSeqiWP_002966521.1. NZ_KN046823.1.

3D structure databases

ProteinModelPortaliQ2YJ83.
SMRiQ2YJ83.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ12223; CAJ12223; BAB2_0057.
GeneIDi3827894.
KEGGibmf:BAB2_0057.
PATRICi17847599. VBIBruMel86222_2333.

Phylogenomic databases

HOGENOMiHOG000289240.
OMAiNSQMAVE.

Family and domain databases

Gene3Di3.30.1330.60. 1 hit.
InterProiView protein in InterPro
IPR006665. OmpA-like.
PfamiView protein in Pfam
PF00691. OmpA. 1 hit.
SUPFAMiSSF103088. SSF103088. 1 hit.
PROSITEiView protein in PROSITE
PS51123. OMPA_2. 1 hit.
PS51257. PROKAR_LIPOPROTEIN. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYP57_BRUA2
AccessioniPrimary (citable) accession number: Q2YJ83
Secondary accession number(s): Q57A25, Q9KIS3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: February 7, 2006
Last modified: February 15, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.