Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q2YJ82

- VIRBB_BRUA2

UniProt

Q2YJ82 - VIRBB_BRUA2

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Type IV secretion system protein VirB11

Gene

virB11

Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice. Virb11 is essential for pathogenesis in mice but is not required for intracellular survival.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi182 – 1898ATPSequence Analysis

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. pathogenesis Source: UniProtKB-KW
  2. transport Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Virulence

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBABO359391:GKDV-2301-MONOMER.
BMEL359391:GJOQ-2301-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Type IV secretion system protein VirB11
Gene namesi
Name:virB11
Ordered Locus Names:BAB2_0058
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719: Chromosome II

Subcellular locationi

Cytoplasm Curated

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 362362Type IV secretion system protein VirB11PRO_0000291436Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi359391.BAB2_0058.

Structurei

3D structure databases

ProteinModelPortaliQ2YJ82.
SMRiQ2YJ82. Positions 12-356.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GSP E family.Curated

Phylogenomic databases

eggNOGiCOG0630.
HOGENOMiHOG000119934.
KOiK03196.
OMAiRGAETYD.
OrthoDBiEOG6X3W2S.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR025662. Sigma_54_int_dom_ATP-bd_1.
IPR001482. T2SS_protein-E.
IPR014155. VirB11.
[Graphical view]
PfamiPF00437. T2SE. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02788. VirB11. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2YJ82-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMSNRSDFIV PDEAAVKRAA SVNFHLEPLR PWLDDPQITE VCVNRPGEVF
60 70 80 90 100
CERASAWEYY AVPNLDYEHL ISLGTATARF VDQDISDSRP VLSAILPMGE
110 120 130 140 150
RIQIVRPPAC EHGTISVTIR KPSFTRRTLE DYAQQGFFKH VRPMSKSLTP
160 170 180 190 200
FEQELLALKE AGDYMSFLRR AVQLERVIVV AGETGSGKTT LMKALMQEIP
210 220 230 240 250
FDQRLITIED VPELFLPDHP NHVHLFYPSE AKEEENAPVT AATLLRSCLR
260 270 280 290 300
MKPTRILLAE LRGGETYDFI NVAASGHGGS ITSCHAGSCE LTFERLALMV
310 320 330 340 350
LQNRQGRQLP YEIIRRLLYL VVDVVVHVHN GVHDGTGRHI SEVWYDPNTK
360
RALSLQHSEK TQ
Length:362
Mass (Da):40,885
Last modified:February 7, 2006 - v1
Checksum:i4C32B060F4FC79BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF226278 Genomic DNA. Translation: AAF73904.1.
AM040265 Genomic DNA. Translation: CAJ12224.1.
RefSeqiYP_418303.1. NC_007624.1.

Genome annotation databases

EnsemblBacteriaiCAJ12224; CAJ12224; BAB2_0058.
GeneIDi3827895.
KEGGibmf:BAB2_0058.
PATRICi17847601. VBIBruMel86222_2334.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF226278 Genomic DNA. Translation: AAF73904.1 .
AM040265 Genomic DNA. Translation: CAJ12224.1 .
RefSeqi YP_418303.1. NC_007624.1.

3D structure databases

ProteinModelPortali Q2YJ82.
SMRi Q2YJ82. Positions 12-356.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 359391.BAB2_0058.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ12224 ; CAJ12224 ; BAB2_0058 .
GeneIDi 3827895.
KEGGi bmf:BAB2_0058.
PATRICi 17847601. VBIBruMel86222_2334.

Phylogenomic databases

eggNOGi COG0630.
HOGENOMi HOG000119934.
KOi K03196.
OMAi RGAETYD.
OrthoDBi EOG6X3W2S.

Enzyme and pathway databases

BioCyci BABO359391:GKDV-2301-MONOMER.
BMEL359391:GJOQ-2301-MONOMER.

Miscellaneous databases

PROi Q2YJ82.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
InterProi IPR027417. P-loop_NTPase.
IPR025662. Sigma_54_int_dom_ATP-bd_1.
IPR001482. T2SS_protein-E.
IPR014155. VirB11.
[Graphical view ]
Pfami PF00437. T2SE. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR02788. VirB11. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A homologue of an operon required for DNA transfer in Agrobacterium is required in Brucella abortus for virulence and intracellular multiplication."
    Sieira R., Comerci D.J., Sanchez D.O., Ugalde R.A.
    J. Bacteriol. 182:4849-4855(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], TRANSCRIPTION, FUNCTION.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiVIRBB_BRUA2
AccessioniPrimary (citable) accession number: Q2YJ82
Secondary accession number(s): Q57A24, Q9KIS5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: February 7, 2006
Last modified: October 29, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Transcription is turned on at the beginning of the stationary phase of vegetative growth.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3