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Protein

60S ribosomal protein L6

Gene

RPL6

Organism
Sus scrofa (Pig)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Component of the large ribosomal subunit.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-SSC-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L6
Gene namesi
Name:RPL6
OrganismiSus scrofa (Pig)
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 14

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001710111 – 28460S ribosomal protein L6Add BLAST284

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki5Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei123PhosphoserineBy similarity1
Modified residuei235N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

PaxDbiQ2YGT9.
PeptideAtlasiQ2YGT9.
PRIDEiQ2YGT9.

Expressioni

Gene expression databases

BgeeiENSSSCG00000024825.
GenevisibleiQ2YGT9. SS.

Interactioni

Subunit structurei

Component of the large ribosomal subunit. May bind IPO9 with low affinity.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000020107.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J7Oelectron microscopy3.40E38-284[»]
3J7Pelectron microscopy3.50E38-284[»]
ProteinModelPortaliQ2YGT9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1694. Eukaryota.
COG2163. LUCA.
GeneTreeiENSGT00390000003682.
HOVERGENiHBG002565.
InParanoidiQ2YGT9.
KOiK02934.
OMAiRKGDKPH.
OrthoDBiEOG091G0L13.
TreeFamiTF300115.

Family and domain databases

Gene3Di2.30.30.30. 1 hit.
InterProiView protein in InterPro
IPR000915. 60S_ribosomal_L6E.
IPR014722. Rib_L2_dom2.
IPR005568. Ribosomal_L6_N.
IPR008991. Translation_prot_SH3-like.
PANTHERiPTHR10715. PTHR10715. 1 hit.
PfamiView protein in Pfam
PF01159. Ribosomal_L6e. 1 hit.
PF03868. Ribosomal_L6e_N. 1 hit.
SUPFAMiSSF50104. SSF50104. 1 hit.
PROSITEiView protein in PROSITE
PS01170. RIBOSOMAL_L6E. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2YGT9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGEKAEKPG TKEKKPEAKK ADAGGKVKKA KKVKKGKPHC SRNPVLVRGI
60 70 80 90 100
GRYSRSAMYS RKALYKRKYS AAKSKVEKKK KVRVLATVTK PVGGDKNGGT
110 120 130 140 150
RVVKLRKMPR YYPTEDVPRK LLSHGKKPFS KHVRKLRASI TPGTILIILT
160 170 180 190 200
GRHRGKRVIF LKQLSSGLLL VTGPLSLNRV PLRRTHQKFV IATSTKIDIS
210 220 230 240 250
GVKIPEHLTD AYFKKKKLRK PRHQEGEIFD TEKEKYEISE QRKVDQKAVD
260 270 280
SQILRRIKAV PQLQGYLRSV FALTNGIYPH KLVF
Length:284
Mass (Da):32,190
Last modified:January 23, 2007 - v3
Checksum:iFA94DFCA7306AE2F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY735452 mRNA. Translation: AAV85770.1.
RefSeqiNP_001038007.1. NM_001044542.1.
UniGeneiSsc.1062.
Ssc.86910.

Genome annotation databases

EnsembliENSSSCT00000024558; ENSSSCP00000020107; ENSSSCG00000024825.
GeneIDi733592.
KEGGissc:733592.

Similar proteinsi

Entry informationi

Entry nameiRL6_PIG
AccessioniPrimary (citable) accession number: Q2YGT9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: January 23, 2007
Last modified: August 30, 2017
This is version 73 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families