SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q2YDL5

- FKB11_BOVIN

UniProt

Q2YDL5 - FKB11_BOVIN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Peptidyl-prolyl cis-trans isomerase FKBP11

Gene
FKBP11
Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

PPIases accelerate the folding of proteins during protein synthesis By similarity.

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).

GO - Molecular functioni

  1. peptidyl-prolyl cis-trans isomerase activity Source: UniProtKB-KW

GO - Biological processi

  1. protein folding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Isomerase, Rotamase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-prolyl cis-trans isomerase FKBP11 (EC:5.2.1.8)
Short name:
PPIase FKBP11
Alternative name(s):
FK506-binding protein 11
Short name:
FKBP-11
Rotamase
Gene namesi
Name:FKBP11
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei158 – 17821Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2929 Reviewed predictionAdd
BLAST
Chaini30 – 203174Peptidyl-prolyl cis-trans isomerase FKBP11PRO_0000285595Add
BLAST

Proteomic databases

PaxDbiQ2YDL5.
PRIDEiQ2YDL5.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000021025.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini59 – 14688PPIase FKBP-typeAdd
BLAST

Sequence similaritiesi

Belongs to the FKBP-type PPIase family.

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0545.
HOGENOMiHOG000154887.
HOVERGENiHBG051623.
InParanoidiQ2YDL5.
KOiK09576.

Family and domain databases

InterProiIPR023566. PPIase_FKBP.
IPR001179. PPIase_FKBP_dom.
[Graphical view]
PANTHERiPTHR10516. PTHR10516. 1 hit.
PfamiPF00254. FKBP_C. 1 hit.
[Graphical view]
PROSITEiPS50059. FKBP_PPIASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2YDL5-1 [UniParc]FASTAAdd to Basket

« Hide

MTLRPSLLPL RLLLLLLLLL RGAVCQAEAG SETESPVRTL QVETLVEPPE    50
PCAEPATFGD TLHIHYSGSL VDGRIFDTSL TRDPLVIELG QKQVIPGLEQ 100
SLLDMCVGEK RRVIIPSHLA YGKRGFPPSI PADAELHFDV ELIALIRANY 150
WQKLVKGILP LVGMAMVPAL LGLIGYHLYR KASSPKISKN KLKEEKRNKS 200
KKK 203
Length:203
Mass (Da):22,475
Last modified:December 20, 2005 - v1
Checksum:i62345FFA86344A45
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC110165 mRNA. Translation: AAI10166.1.
RefSeqiNP_001039397.1. NM_001045932.1.
UniGeneiBt.55432.

Genome annotation databases

GeneIDi506043.
KEGGibta:506043.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC110165 mRNA. Translation: AAI10166.1 .
RefSeqi NP_001039397.1. NM_001045932.1.
UniGenei Bt.55432.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9913.ENSBTAP00000021025.

Proteomic databases

PaxDbi Q2YDL5.
PRIDEi Q2YDL5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 506043.
KEGGi bta:506043.

Organism-specific databases

CTDi 51303.

Phylogenomic databases

eggNOGi COG0545.
HOGENOMi HOG000154887.
HOVERGENi HBG051623.
InParanoidi Q2YDL5.
KOi K09576.

Miscellaneous databases

NextBioi 20867422.

Family and domain databases

InterProi IPR023566. PPIase_FKBP.
IPR001179. PPIase_FKBP_dom.
[Graphical view ]
PANTHERi PTHR10516. PTHR10516. 1 hit.
Pfami PF00254. FKBP_C. 1 hit.
[Graphical view ]
PROSITEi PS50059. FKBP_PPIASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Crossbred X Angus.
    Tissue: Liver.

Entry informationi

Entry nameiFKB11_BOVIN
AccessioniPrimary (citable) accession number: Q2YDL5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: December 20, 2005
Last modified: July 9, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi