Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q2YDL5 (FKB11_BOVIN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Peptidyl-prolyl cis-trans isomerase FKBP11

Short name=PPIase FKBP11
EC=5.2.1.8
Alternative name(s):
FK506-binding protein 11
Short name=FKBP-11
Rotamase
Gene names
Name:FKBP11
OrganismBos taurus (Bovine) [Reference proteome]
Taxonomic identifier9913 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Protein attributes

Sequence length203 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

PPIases accelerate the folding of proteins during protein synthesis By similarity.

Catalytic activity

Peptidylproline (omega=180) = peptidylproline (omega=0).

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

Belongs to the FKBP-type PPIase family.

Contains 1 PPIase FKBP-type domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2929 Potential
Chain30 – 203174Peptidyl-prolyl cis-trans isomerase FKBP11
PRO_0000285595

Regions

Transmembrane158 – 17821Helical; Potential
Domain59 – 14688PPIase FKBP-type

Sequences

Sequence LengthMass (Da)Tools
Q2YDL5 [UniParc].

Last modified December 20, 2005. Version 1.
Checksum: 62345FFA86344A45

FASTA20322,475
        10         20         30         40         50         60 
MTLRPSLLPL RLLLLLLLLL RGAVCQAEAG SETESPVRTL QVETLVEPPE PCAEPATFGD 

        70         80         90        100        110        120 
TLHIHYSGSL VDGRIFDTSL TRDPLVIELG QKQVIPGLEQ SLLDMCVGEK RRVIIPSHLA 

       130        140        150        160        170        180 
YGKRGFPPSI PADAELHFDV ELIALIRANY WQKLVKGILP LVGMAMVPAL LGLIGYHLYR 

       190        200 
KASSPKISKN KLKEEKRNKS KKK 

« Hide

References

[1]NIH - Mammalian Gene Collection (MGC) project
Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Crossbred X Angus.
Tissue: Liver.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC110165 mRNA. Translation: AAI10166.1.
RefSeqNP_001039397.1. NM_001045932.1.
UniGeneBt.55432.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9913.ENSBTAP00000021025.

Proteomic databases

PaxDbQ2YDL5.
PRIDEQ2YDL5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID506043.
KEGGbta:506043.

Organism-specific databases

CTD51303.

Phylogenomic databases

eggNOGCOG0545.
HOGENOMHOG000154887.
HOVERGENHBG051623.
InParanoidQ2YDL5.
KOK09576.

Family and domain databases

InterProIPR023566. PPIase_FKBP.
IPR001179. PPIase_FKBP_dom.
[Graphical view]
PANTHERPTHR10516. PTHR10516. 1 hit.
PfamPF00254. FKBP_C. 1 hit.
[Graphical view]
PROSITEPS50059. FKBP_PPIASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20867422.

Entry information

Entry nameFKB11_BOVIN
AccessionPrimary (citable) accession number: Q2YDL5
Entry history
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: December 20, 2005
Last modified: April 16, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families