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Protein

Sperm acrosome membrane-associated protein 1

Gene

SPACA1

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in sperm-egg fusion.By similarity

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Sperm acrosome membrane-associated protein 1
Gene namesi
Name:SPACA1
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini30 – 221192ExtracellularSequence analysisAdd
BLAST
Transmembranei222 – 24221HelicalSequence analysisAdd
BLAST
Topological domaini243 – 27937CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2929Sequence analysisAdd
BLAST
Chaini30 – 279250Sperm acrosome membrane-associated protein 1PRO_0000248151Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi31 – 311N-linked (GlcNAc...)Sequence analysis
Modified residuei275 – 2751PhosphoserineBy similarity

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiQ2YDG7.
PRIDEiQ2YDG7.

Family & Domainsi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IFV6. Eukaryota.
ENOG410YPX9. LUCA.
HOGENOMiHOG000049221.
HOVERGENiHBG080320.
InParanoidiQ2YDG7.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2YDG7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSRGAGCSA RLLLTVGWLL LAGLQSTCGI NVTAIQDPSL AREGEGEPEG
60 70 80 90 100
DEEPENDSET EKEPQAEAED DSEGIGIREV ILTSGCPGGE SKCIVRVEEC
110 120 130 140 150
RGPVDCGWGR PISESLEHVR LACVHTSPEN RFKYIWRLLR PDQQAIILAN
160 170 180 190 200
DSAILEVHRD THPKAFECET LDNNEIVASI RFTIYTTTEL QMKRASRPDT
210 220 230 240 250
DAVLVFVLTI GVIICIFVIF VLIFIIINWT AVKDFWAKAS TTEIQSELSS
260 270
MRYKDSTSLD QSPTDIPGHE DDALSEWNE
Length:279
Mass (Da):30,939
Last modified:December 20, 2005 - v1
Checksum:iF1ACB2C1882A012F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC110228 mRNA. Translation: AAI10229.1.
RefSeqiNP_001040010.1. NM_001046545.1.
UniGeneiBt.55305.

Genome annotation databases

GeneIDi614884.
KEGGibta:614884.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC110228 mRNA. Translation: AAI10229.1.
RefSeqiNP_001040010.1. NM_001046545.1.
UniGeneiBt.55305.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiQ2YDG7.
PRIDEiQ2YDG7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi614884.
KEGGibta:614884.

Organism-specific databases

CTDi81833.

Phylogenomic databases

eggNOGiENOG410IFV6. Eukaryota.
ENOG410YPX9. LUCA.
HOGENOMiHOG000049221.
HOVERGENiHBG080320.
InParanoidiQ2YDG7.

Miscellaneous databases

NextBioi20899339.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Crossbred X Angus.
    Tissue: Liver.

Entry informationi

Entry nameiSACA1_BOVIN
AccessioniPrimary (citable) accession number: Q2YDG7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: December 20, 2005
Last modified: November 11, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.