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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciNMUL323848:G1GTI-212-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:Nmul_A0206
OrganismiNitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71)
Taxonomic identifieri323848 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesNitrosomonadaceaeNitrosospira
Proteomesi
  • UP000002718 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000120721 – 275Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST275

Interactioni

Protein-protein interaction databases

STRINGi323848.Nmul_A0206

Structurei

3D structure databases

ProteinModelPortaliQ2YCK7
SMRiQ2YCK7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DDT Bacteria
COG0639 LUCA
HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP
OrthoDBiPOG091H0691

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

Q2YCK7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIYAVGDLQ GCYREFRELL DLVRFDETKD KLWLVGDLVN RGPDSLSVLR
60 70 80 90 100
FVKELNDSAI MVLGNHDLHL LLVAEGCAEL SRSDTLQNIL DAPDRDELLD
110 120 130 140 150
WLRRQKLLHV DGNYVMVHAG LLPSWSIEQA QVLAALVESA LRGSEFHEFC
160 170 180 190 200
RQMYGNRPDH WNETLHGYER LRVIVNAMTR MRVCTPHGRM DFAHKGSVKD
210 220 230 240 250
IPPGYLPWFD VPERASRKAT VICGHWSALG LEIRANLMAL DTGCLWGGSL
260 270
TAVRLEDRKV FQTECGAGGA TRHWQ
Length:275
Mass (Da):31,163
Last modified:December 20, 2005 - v1
Checksum:i49423CA8D4EE8621
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000103 Genomic DNA Translation: ABB73514.1
RefSeqiWP_011379568.1, NZ_FNVK01000010.1

Genome annotation databases

EnsemblBacteriaiABB73514; ABB73514; Nmul_A0206
KEGGinmu:Nmul_A0206

Similar proteinsi

Entry informationi

Entry nameiAPAH_NITMU
AccessioniPrimary (citable) accession number: Q2YCK7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 20, 2005
Last modified: May 23, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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