Q2YCJ9 (Q2YCJ9_NITMU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase RuleBase RU003981 HAMAP MF_00259
EC=2.1.2.10 RuleBase RU003981 HAMAP MF_00259

Alternative name(s):
Glycine cleavage system T protein HAMAP MF_00259

Gene names

Name:	gcvT HAMAP MF_00259
Ordered Locus Names:	Nmul_A0214

Organism

Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849) [Complete proteome] [HAMAP] EMBL ABB73522.1

Taxonomic identifier

323848 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Nitrosomonadales › Nitrosomonadaceae › Nitrosospira

Protein attributes

Sequence length	360 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. RuleBase RU003981 HAMAP MF_00259 SAAS SAAS022903
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. RuleBase RU003981 HAMAP MF_00259 SAAS SAAS022903
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. RuleBase RU003981 HAMAP MF_00259 SAAS SAAS022903
Sequence similarities	Belongs to the GcvT family. HAMAP MF_00259 RuleBase RU003980

Ontologies

Keywords
Molecular function	Aminotransferase RuleBase RU003981 HAMAP MF_00259 SAAS SAAS022903 Methyltransferase EMBL ABB73522.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine decarboxylation via glycine cleavage system Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: HAMAP transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2YCJ9 [UniParc]. Last modified December 20, 2005. Version 1. Checksum: E766C37DBFC97DFE	FASTA	360	39,709
	10 20 30 40 50 60 MKTTPLNQTH RDMNAKMVDF GGWDMPLHYG SQLDEHHKVR SDAGMFDVSH MLAVDIEGES 70 80 90 100 110 120 ARAFLRQLVA NNIDKLTQLG KALYSCMLNP DGGVIDDLII YFLTESHFRM VVNAGTADKD 130 140 150 160 170 180 MAWMLSQRDR IAPGLEITPR RDLAMIAVQG PNARAKVWQV LPGSQTDTEN LKLFQAAFFD 190 200 210 220 230 240 KYFIARTGYT GEDGFEITLP AADATNFWNK LHAAGVAPAG LGARDTLRLE AGMNLYGQDM 250 260 270 280 290 300 DETINPLEAG LGWTVDLKSD RDFIGKQALL DRPVTQQLTG LVLLDRGVLR SHQKVVTQND 310 320 330 340 350 360 GGEGEITSGG FSPTLNQSIA LARLPLDVSP GDEVQVVVRD KRLKAKVVKY PFVRNGKILV

References

[1]

"Complete sequence of chromosome 1 of Nitrosospira multiformis ATCC 25196." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Richardson P. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000103 Genomic DNA. Translation: ABB73522.1.
RefSeq	YP_410914.1. NC_007614.1.
3D structure databases
ProteinModelPortal	Q2YCJ9.
SMR	Q2YCJ9. Positions 4-359.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2YCJ9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3784591.
GenomeReviews	Gene locus Nmul_A0214 in contig CP000103_GR.
KEGG	nmu:Nmul_A0214.
PATRIC	22723314. VBINitMul110821_0243.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0404.
HOGENOM	HBG299834.
OMA	GESARAF.
PhylomeDB	Q2YCJ9.
ProtClustDB	PRK00389.
Enzyme and pathway databases
BioCyc	NMUL323848:NMUL_A0214-MONOMER.
Family and domain databases
HAMAP	MF_00259. GcvT. [Tree]
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. IPR022903. NH2_Me_Trfase. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q2YCJ9_NITMU

Accession

Primary (citable) accession number: Q2YCJ9

Entry history

Integrated into UniProtKB/TrEMBL:	December 20, 2005
Last sequence update:	December 20, 2005
Last modified:	December 14, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)