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Q2YAZ9

- EFTU_NITMU

UniProt

Q2YAZ9 - EFTU_NITMU

Protein

Elongation factor Tu

Gene

tuf1

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Organism
Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 1 (20 Dec 2005)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi81 – 855GTPUniRule annotation
    Nucleotide bindingi136 – 1394GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciNMUL323848:GKEC-772-MONOMER.
    NMUL323848:GKEC-786-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tuf1UniRule annotation
    Ordered Locus Names:Nmul_A0752
    AND
    Name:tuf2UniRule annotation
    Ordered Locus Names:Nmul_A0765
    OrganismiNitrosospira multiformis (strain ATCC 25196 / NCIMB 11849)
    Taxonomic identifieri323848 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesNitrosomonadaceaeNitrosospira
    ProteomesiUP000002718: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 396396Elongation factor TuPRO_0000337447Add
    BLAST

    Proteomic databases

    PRIDEiQ2YAZ9.

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi323848.Nmul_A0765.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2YAZ9.
    SMRiQ2YAZ9. Positions 2-395.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini10 – 206197tr-type GAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni19 – 268G1By similarity
    Regioni60 – 645G2By similarity
    Regioni81 – 844G3By similarity
    Regioni136 – 1394G4By similarity
    Regioni174 – 1763G5By similarity

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0050.
    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiGTEMCMP.
    OrthoDBiEOG6R5C6X.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2YAZ9-1 [UniParc]FASTAAdd to Basket

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    MAKSKFERTK PHINVGTIGH VDHGKTTLTA AITMVLAKKF GGEAKSYAQI    50
    DSAPEEKARG ITINTSHVEY ETEKRHYAHV DCPGHADYVK NMITGAAQMD 100
    GAILVVSAAD GPMPQTREHI LLARQVGVPY IIVYMNKADM VDDAELLELV 150
    EMEVRELLSK YNFPGDDTPI VIGSALKALE GDQSDIGEPS IYKLAAALDS 200
    YIPEPQRAVD GAFLMPVEDV FSISGRGTVV TGRVERGVIK VGEDIEIVGL 250
    KPTTKTVCTG VEMFRKLLDQ GQAGDNVGVL LRGTKREEVE RGQVLAKPGT 300
    ITPHTKFTAE IYVLSKEEGG RHTPFFQGYR PQFYFRTTDV TGAIELPAGT 350
    EMVMPGDNVS VTVNLIAPIA MEEGLRFAIR EGGRTVGAGV VAKIIE 396
    Length:396
    Mass (Da):42,925
    Last modified:December 20, 2005 - v1
    Checksum:i382644477F2FCC00
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000103 Genomic DNA. Translation: ABB74059.1.
    CP000103 Genomic DNA. Translation: ABB74072.1.
    RefSeqiYP_411451.1. NC_007614.1.
    YP_411464.1. NC_007614.1.

    Genome annotation databases

    EnsemblBacteriaiABB74059; ABB74059; Nmul_A0752.
    ABB74072; ABB74072; Nmul_A0765.
    GeneIDi3785218.
    3786487.
    KEGGinmu:Nmul_A0752.
    nmu:Nmul_A0765.
    PATRICi22724596. VBINitMul110821_0870.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000103 Genomic DNA. Translation: ABB74059.1 .
    CP000103 Genomic DNA. Translation: ABB74072.1 .
    RefSeqi YP_411451.1. NC_007614.1.
    YP_411464.1. NC_007614.1.

    3D structure databases

    ProteinModelPortali Q2YAZ9.
    SMRi Q2YAZ9. Positions 2-395.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 323848.Nmul_A0765.

    Proteomic databases

    PRIDEi Q2YAZ9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABB74059 ; ABB74059 ; Nmul_A0752 .
    ABB74072 ; ABB74072 ; Nmul_A0765 .
    GeneIDi 3785218.
    3786487.
    KEGGi nmu:Nmul_A0752.
    nmu:Nmul_A0765.
    PATRICi 22724596. VBINitMul110821_0870.

    Phylogenomic databases

    eggNOGi COG0050.
    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi GTEMCMP.
    OrthoDBi EOG6R5C6X.

    Enzyme and pathway databases

    BioCyci NMUL323848:GKEC-772-MONOMER.
    NMUL323848:GKEC-786-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome 1 of Nitrosospira multiformis ATCC 25196."
      Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Richardson P.
      Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 25196 / NCIMB 11849.

    Entry informationi

    Entry nameiEFTU_NITMU
    AccessioniPrimary (citable) accession number: Q2YAZ9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: December 20, 2005
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3