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Q2Y7W4

- TRUB_NITMU

UniProt

Q2Y7W4 - TRUB_NITMU

Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 55 (01 Oct 2014)
      Sequence version 1 (20 Dec 2005)
      Previous versions | rss
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    • Comment

    Functioni

    Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

    Catalytic activityi

    tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei46 – 461NucleophileUniRule annotation

    GO - Molecular functioni

    1. pseudouridine synthase activity Source: UniProtKB-HAMAP
    2. RNA binding Source: InterPro

    GO - Biological processi

    1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    tRNA processing

    Enzyme and pathway databases

    BioCyciNMUL323848:GKEC-1896-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
    Alternative name(s):
    tRNA pseudouridine(55) synthaseUniRule annotation
    Short name:
    Psi55 synthaseUniRule annotation
    tRNA pseudouridylate synthaseUniRule annotation
    tRNA-uridine isomeraseUniRule annotation
    Gene namesi
    Name:truBUniRule annotation
    Ordered Locus Names:Nmul_A1862
    OrganismiNitrosospira multiformis (strain ATCC 25196 / NCIMB 11849)
    Taxonomic identifieri323848 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesNitrosomonadaceaeNitrosospira
    ProteomesiUP000002718: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 313313tRNA pseudouridine synthase BPRO_0000229365Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi323848.Nmul_A1862.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2Y7W4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0130.
    HOGENOMiHOG000231223.
    KOiK03177.
    OMAiYELQFIR.
    OrthoDBiEOG6358D3.

    Family and domain databases

    Gene3Di2.30.130.10. 1 hit.
    HAMAPiMF_01080. TruB_bact.
    InterProiIPR002501. PsdUridine_synth.
    IPR020103. PsdUridine_synth_cat_dom.
    IPR015947. PUA-like_domain.
    IPR014780. tRNA_psdUridine_synth_TruB.
    IPR015240. tRNA_sdUridine_synth_fam1_C.
    [Graphical view]
    PANTHERiPTHR13767. PTHR13767. 1 hit.
    PfamiPF09157. TruB-C_2. 1 hit.
    PF01509. TruB_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF55120. SSF55120. 1 hit.
    SSF88697. SSF88697. 1 hit.
    TIGRFAMsiTIGR00431. TruB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q2Y7W4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSPGSKRHIS GVLLLDKASG LSSNQALQTA KRIFSAHKAG HTGTLDPMAT    50
    GLLPICFGEA TKFSSALLGA DKTYEAVLRL GYMSTTGDAE GEISIAAGME 100
    SQYVDLTREK IEAVRKSFIG VITQVPPMYS AIKHRGKPMY TFARAGVEIE 150
    RQPRAITIHD LSIEAYQGNE MRIRVTCGSG TYIRTLAEDL GHALGCGGAY 200
    LTALRRSALG GFDLPQAYTL TGLEAMPPSQ RDSCLLPADS LLRSLPPVVV 250
    DSAAALSLLQ GRAIPGTHPA GESLLPGRQV RLYDKAQRFL GLGEISTEGY 300
    ISPKRLIRFE QSL 313
    Length:313
    Mass (Da):33,564
    Last modified:December 20, 2005 - v1
    Checksum:iA3FD1CF30B6604ED
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000103 Genomic DNA. Translation: ABB75157.1.
    RefSeqiYP_412549.1. NC_007614.1.

    Genome annotation databases

    EnsemblBacteriaiABB75157; ABB75157; Nmul_A1862.
    GeneIDi3786606.
    KEGGinmu:Nmul_A1862.
    PATRICi22727236. VBINitMul110821_2177.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000103 Genomic DNA. Translation: ABB75157.1 .
    RefSeqi YP_412549.1. NC_007614.1.

    3D structure databases

    ProteinModelPortali Q2Y7W4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 323848.Nmul_A1862.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABB75157 ; ABB75157 ; Nmul_A1862 .
    GeneIDi 3786606.
    KEGGi nmu:Nmul_A1862.
    PATRICi 22727236. VBINitMul110821_2177.

    Phylogenomic databases

    eggNOGi COG0130.
    HOGENOMi HOG000231223.
    KOi K03177.
    OMAi YELQFIR.
    OrthoDBi EOG6358D3.

    Enzyme and pathway databases

    BioCyci NMUL323848:GKEC-1896-MONOMER.

    Family and domain databases

    Gene3Di 2.30.130.10. 1 hit.
    HAMAPi MF_01080. TruB_bact.
    InterProi IPR002501. PsdUridine_synth.
    IPR020103. PsdUridine_synth_cat_dom.
    IPR015947. PUA-like_domain.
    IPR014780. tRNA_psdUridine_synth_TruB.
    IPR015240. tRNA_sdUridine_synth_fam1_C.
    [Graphical view ]
    PANTHERi PTHR13767. PTHR13767. 1 hit.
    Pfami PF09157. TruB-C_2. 1 hit.
    PF01509. TruB_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55120. SSF55120. 1 hit.
    SSF88697. SSF88697. 1 hit.
    TIGRFAMsi TIGR00431. TruB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome 1 of Nitrosospira multiformis ATCC 25196."
      Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Richardson P.
      Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 25196 / NCIMB 11849.

    Entry informationi

    Entry nameiTRUB_NITMU
    AccessioniPrimary (citable) accession number: Q2Y7W4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2006
    Last sequence update: December 20, 2005
    Last modified: October 1, 2014
    This is version 55 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3