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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei46NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciNMUL323848:G1GTI-1948-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:Nmul_A1862
OrganismiNitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71)
Taxonomic identifieri323848 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesNitrosomonadaceaeNitrosospira
Proteomesi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002293651 – 313tRNA pseudouridine synthase BAdd BLAST313

Interactioni

Protein-protein interaction databases

STRINGi323848.Nmul_A1862

Structurei

3D structure databases

ProteinModelPortaliQ2Y7W4
SMRiQ2Y7W4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T Bacteria
COG0130 LUCA
HOGENOMiHOG000231223
KOiK03177
OMAiVDCSKGT
OrthoDBiPOG091H02G9

Family and domain databases

Gene3Di2.30.130.10, 1 hit
HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR015947 PUA-like_sf
IPR036974 PUA_sf
IPR014780 tRNA_psdUridine_synth_TruB
IPR015240 tRNA_sdUridine_synth_fam1_C
IPR032819 TruB_C
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF09157 TruB-C_2, 1 hit
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
SSF88697 SSF88697, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

Q2Y7W4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPGSKRHIS GVLLLDKASG LSSNQALQTA KRIFSAHKAG HTGTLDPMAT
60 70 80 90 100
GLLPICFGEA TKFSSALLGA DKTYEAVLRL GYMSTTGDAE GEISIAAGME
110 120 130 140 150
SQYVDLTREK IEAVRKSFIG VITQVPPMYS AIKHRGKPMY TFARAGVEIE
160 170 180 190 200
RQPRAITIHD LSIEAYQGNE MRIRVTCGSG TYIRTLAEDL GHALGCGGAY
210 220 230 240 250
LTALRRSALG GFDLPQAYTL TGLEAMPPSQ RDSCLLPADS LLRSLPPVVV
260 270 280 290 300
DSAAALSLLQ GRAIPGTHPA GESLLPGRQV RLYDKAQRFL GLGEISTEGY
310
ISPKRLIRFE QSL
Length:313
Mass (Da):33,564
Last modified:December 20, 2005 - v1
Checksum:iA3FD1CF30B6604ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000103 Genomic DNA Translation: ABB75157.1
RefSeqiWP_011381177.1, NZ_FNVK01000004.1

Genome annotation databases

EnsemblBacteriaiABB75157; ABB75157; Nmul_A1862
KEGGinmu:Nmul_A1862

Similar proteinsi

Entry informationi

Entry nameiTRUB_NITMU
AccessioniPrimary (citable) accession number: Q2Y7W4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: December 20, 2005
Last modified: May 23, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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