Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q2Y6Y0 (Q2Y6Y0_NITMU) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase HAMAP MF_00387
Short name=UDP-N-acetylglucosamine acyltransferase HAMAP MF_00387
EC=2.3.1.129 HAMAP MF_00387
Gene names
Name:lpxA HAMAP MF_00387
Ordered Locus Names:Nmul_A2199
OrganismNitrosospira multiformis (strain ATCC 25196 / NCIMB 11849) [Complete proteome] [HAMAP] EMBL ABB75491.1
Taxonomic identifier323848 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Nitrosomonadales › Nitrosomonadaceae › Nitrosospira

Protein attributes

Sequence length260 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. HAMAP MF_00387 SAAS SAAS010137

Catalytic activity

(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetylglucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. HAMAP MF_00387 SAAS SAAS010137

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. HAMAP MF_00387 SAAS SAAS010137

Subunit structure

Homotrimer By similarity. HAMAP MF_00387 SAAS SAAS010137

Subcellular location

Cytoplasm By similarity HAMAP MF_00387 SAAS SAAS010137.

Sequence similarities

Belongs to the transferase hexapeptide repeat family. LpxA subfamily. HAMAP MF_00387

Sequences

Sequence LengthMass (Da)Tools
Q2Y6Y0 [UniParc].

Last modified December 20, 2005. Version 1.
Checksum: 443D79B28DF9C40E

FASTA26028,286
        10         20         30         40         50         60 
MKEASIHPTA VVHPGAQLGS GVTIGAYSIV EEHVAVGDDT WIGPHVVIKG HTRVGDNNRI 

        70         80         90        100        110        120 
FQFCSLGDEP QDKKYKGEPT RLEIGDRNTI REFCTFNRGT AQGAGVTRLG NDNFVMAYVH 

       130        140        150        160        170        180 
LAHDCQVGNF TTFTNNASLA GHVQVGDYAG LGGFTSVHQF VRVGAYSFTG LGTVLTQDLP 

       190        200        210        220        230        240 
PYLLAAGNPA MPYGLNWREL KRRGFSESTL RALKSAYKLV YRSGLALKEA EAQLMQLAGD 

       250        260 
TPSVQRFLDF ISVRGRGIIR

« Hide

References

[1]"Complete sequence of chromosome 1 of Nitrosospira multiformis ATCC 25196."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000103 Genomic DNA. Translation: ABB75491.1.
RefSeqYP_412883.1. NC_007614.1.

3D structure databases

ProteinModelPortalQ2Y6Y0.
SMRQ2Y6Y0. Positions 2-260.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2Y6Y0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3786224.
GenomeReviewsGene locus Nmul_A2199 in contig CP000103_GR.
KEGGnmu:Nmul_A2199.
PATRIC22728022. VBINitMul110821_2566.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1043.
HOGENOMHBG659295.
OMAREFCTFN.
PhylomeDBQ2Y6Y0.

Enzyme and pathway databases

BioCycNMUL323848:NMUL_A2199-MONOMER.

Family and domain databases

HAMAPMF_00387. LpxA.
[Tree]
InterProIPR001451. Hexapep_transf.
IPR010137. Lipid_A_lpxA.
IPR011004. Trimer_LpxA-like.
[Graphical view]
KOK00677.
PfamPF00132. Hexapep. 3 hits.
[Graphical view]
PIRSFPIRSF000456. UDP-GlcNAc_acltr. 1 hit.
SUPFAMSSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMsTIGR01852. Lipid_A_lpxA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ2Y6Y0_NITMU
AccessionPrimary (citable) accession number: Q2Y6Y0
Entry history
Integrated into UniProtKB/TrEMBL: December 20, 2005
Last sequence update: December 20, 2005
Last modified: December 14, 2011
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info