Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Arginine--tRNA ligase

Gene

argS

Organism
Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciNMUL323848:G1GTI-2555-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Nmul_A2456
OrganismiNitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71)
Taxonomic identifieri323848 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesNitrosomonadaceaeNitrosospira
Proteomesi
  • UP000002718 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002420571 – 581Arginine--tRNA ligaseAdd BLAST581

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi323848.Nmul_A2456

Structurei

3D structure databases

ProteinModelPortaliQ2Y676
SMRiQ2Y676
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi131 – 141"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 2 hits
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q2Y676-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPPVQPDFK SHFTDILRNA LNERGLADLN LDIEFARPRQ SSHGDYSCNL
60 70 80 90 100
AMQLAKPLRQ KPRDIAQSLA TAFSASPYLE KVEIAGAGFI NLFLTTSAKQ
110 120 130 140 150
QFSRYVLESG EKFGHSSMGA GEKIQVEFVS ANPTGPLHVG HGRGAAFGAS
160 170 180 190 200
LANVLAAAGY SVTREYYIND AGRQMDILAL STWLRYLELN GVASAFPPNA
210 220 230 240 250
YQGEYVRDMA RLIHKAHAGR YVHEPELLFD RVAGAEADTE AALDGLIANA
260 270 280 290 300
KKLLGQDYAY IHNFVLNEQL GDCRNDLMEF GVTFDIWFSE QSLFDSGGVA
310 320 330 340 350
QAVHLLEEGN YLYQQDGAKW FRSSHFGDEK DRVVQRENGQ FTYFASDIAY
360 370 380 390 400
HLNKFSRGFD RVIDIWGADH HGYISRVKGA MQALALDPEK LEIALVQFAV
410 420 430 440 450
LYRDGKKVPM STRAGEFVTL RELRQEVGTD AARFFYVLRK SDQHLDFDLD
460 470 480 490 500
LAKSQSTDNP VYYVQYAHAR VCSVLEQWGE DPGMLVTADT SALTGAAELS
510 520 530 540 550
LLQKLIDYPE TVEAAAREFS PHLIAFYLKE LAGEFHSYYN STRFLVPEMT
560 570 580
VRLARLALVA AVRQVLNNGL KLLGVSAPAK M
Length:581
Mass (Da):64,698
Last modified:June 27, 2006 - v2
Checksum:i95CCF9C2BAF3D7D9
GO

Sequence cautioni

The sequence ABB75745 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000103 Genomic DNA Translation: ABB75745.1 Different initiation.
RefSeqiWP_049783179.1, NZ_FNVK01000014.1

Genome annotation databases

EnsemblBacteriaiABB75745; ABB75745; Nmul_A2456
KEGGinmu:Nmul_A2456

Similar proteinsi

Entry informationi

Entry nameiSYR_NITMU
AccessioniPrimary (citable) accession number: Q2Y676
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: June 27, 2006
Last modified: June 20, 2018
This is version 79 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health