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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei139GTPUniRule annotation1
Binding sitei142GTPUniRule annotation1
Binding sitei186GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi108 – 110GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciNMUL323848:G1GTI-2586-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:Nmul_A2488Imported
ORF Names:SAMN05216403_105124Imported
OrganismiNitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71)Imported
Taxonomic identifieri323848 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesNitrosomonadaceaeNitrosospira
Proteomesi
  • UP000236751 Componenti: Unassembled WGS sequence
  • UP000002718 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi323848.Nmul_A2488

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 204TubulinInterPro annotationAdd BLAST192
Domaini206 – 324Tubulin_CInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI
OrthoDBiPOG091H02KK

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q2Y644-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFEIMDTQTQ EAVIKVIGVG GCGGNAVDHM MENGVQGVDF ICANTDSQAL
60 70 80 90 100
KRNQARTLVQ LGSTITKGLG AGADPEIGRH AALEDRDRIA ELIEGADMLF
110 120 130 140 150
ITAGMGGGTG TGAAPVVAQV AREMGILTVA VVTKPFVFEG RRVRAAQAGL
160 170 180 190 200
EALAQYVDSL IVIPNDKLMA VLGEEVSMLD AFKAANNVLY SAVAGIAEVI
210 220 230 240 250
NCPGLVNVDF ADVKTVMSEM GMAMMGSAIA CGPDRARAAA EQAVASPLLE
260 270 280 290 300
DINLAGARGV LVNITANAAM KMREVHDVMN TIKDFTAEDA TVIVGTVIDD
310 320 330 340 350
DMHDDLRVTV VATGLGGVGL GGATRVPPKP LSVVHPRAAM DNIDPMNWKD
360 370 380
SEGPASIRTN RQRDAAVEAM RQSGVDILDI PAFLRKQAD
Length:389
Mass (Da):40,707
Last modified:December 20, 2005 - v1
Checksum:i6F1AC2C9216425FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000103 Genomic DNA Translation: ABB75777.1
FNVK01000005 Genomic DNA Translation: SEF66763.1
RefSeqiWP_011381776.1, NC_007614.1

Genome annotation databases

EnsemblBacteriaiABB75777; ABB75777; Nmul_A2488
KEGGinmu:Nmul_A2488

Similar proteinsi

Entry informationi

Entry nameiQ2Y644_NITMU
AccessioniPrimary (citable) accession number: Q2Y644
Entry historyiIntegrated into UniProtKB/TrEMBL: December 20, 2005
Last sequence update: December 20, 2005
Last modified: April 25, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health