Q2Y5Q1 (GLND_NITMU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:	glnD
Ordered Locus Names:	Nmul_A2633

Organism

Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849) [Complete proteome] [HAMAP]

Taxonomic identifier

323848 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Nitrosomonadales › Nitrosomonadaceae › Nitrosospira › Nitrosospira multiformis

Protein attributes

Sequence length	887 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein By similarity. HAMAP-Rule MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP-Rule MF_00277
Sequence similarities	Belongs to the GlnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	nitrogen fixation Inferred from electronic annotation. Source: HAMAP
Molecular_function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 887	887	[Protein-PII] uridylyltransferase HAMAP-Rule MF_00277		PRO_0000231684

Sequences

	Sequence		Length	Mass (Da)
	Q2Y5Q1 [UniParc]. Last modified December 20, 2005. Version 1. Checksum: E65E0364AA37D84B	FASTA	887	101,510
	10 20 30 40 50 60 MKGLNAKPFS HEAVRQKLLS GRESLQRRYH QNRNGAALLR DHSRLVDGIL RQVWHEMNMP 70 80 90 100 110 120 GSTALLAVGG YGRRQLFPYS DIDLVVLLPD KGDAAEAMDN ELGTRLEHWV GLLWDIGLDI 130 140 150 160 170 180 GHSVRTVKEC GEEAANDITV QTSLLEARLL GGNSDLFDRF LQVMETMLAP RKFFVDKQLE 190 200 210 220 230 240 QQQRHKRYQD APYKLEPNIK ESPGGLRDLQ NVLWISRAAG FGKTWSELAK KGFIIRREAR 250 260 270 280 290 300 LIQRQQTVLQ DLRIRLHYLG GRREDRLLFD YQNPLAEELG IAAKPPRRPG EMLMQRYYRA 310 320 330 340 350 360 ARSVTQVNTI LLLTLHAEIF PDEEAVTTII NERFQKRGDL LEICEEDIFE RDPGAILESV 370 380 390 400 410 420 LLLQQNPDLK GRSFATLRAM WRSAPLITAS FRREPRHCAM FMEILRQPRG LTRELRLMNR 430 440 450 460 470 480 YGILGRYIPA FGRIIGQMQH DLFHVYTVDE HILMVVRNLR RFMAPEFAYE YPLCSRLINE 490 500 510 520 530 540 FERPELLYLA GLFHDIAKGR QGDHSLLGKV DARRFCERHR MPAEDTELVV WLVENHLHMS 550 560 570 580 590 600 ATAQKKDIAD AEVIADFAAS MRDERHLIAL YLLTVSDIRG TSPKVWNAWK GKLLEDLFHR 610 620 630 640 650 660 TRQYLCGETA LTDISLENRK NKVLQLLHPD DAAMRAYERF WSGLDSSYLM MHDPREIAWH 670 680 690 700 710 720 TQHLSQRMKS PAPIVKTRAA ETGAGVEVLV YTADQKDLFA RICSFFDGID YNIVQAKIHT 730 740 750 760 770 780 TREGYALDSF LVLDPFNVAN HDPREFQFIE QELTQQLEQQ ALMATPVKGR LSRHLRHFPI 790 800 810 820 830 840 TPQVSIEPDD SGAYYVLSIT AGDQSGLLSR IAQVLVRFGL NVHSARINTL GERAEDTFLV 850 860 870 880 TGSILSNSRS VIQLEANLIK VLHTSPQPET PGKAPGKPSA GDRIIPR

References

[1]

"Complete sequence of chromosome 1 of Nitrosospira multiformis ATCC 25196." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Richardson P. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25196 / NCIMB 11849.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000103 Genomic DNA. Translation: ABB75920.1.
RefSeq	YP_413312.1. NC_007614.1.
3D structure databases
ProteinModelPortal	Q2Y5Q1.
ModBase	Search...
Protein-protein interaction databases
STRING	323848.Nmul_A2633.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABB75920; ABB75920; Nmul_A2633.
GeneID	3786336.
KEGG	nmu:Nmul_A2633.
PATRIC	22729016. VBINitMul110821_3056.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HOG000261778.
KO	K00990.
OMA	SPKVWNA.
ProtClustDB	PRK03059.
Family and domain databases
Gene3D	1.10.3210.10. 1 hit.
HAMAP	MF_00277. PII_uridylyl-transf.
InterPro	IPR002912. ACT_dom. IPR010043. GlnD_Uridyltrans. IPR003607. HD/PDEase_dom. IPR006674. HD_domain. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. PTHR13734:SF1. 1 hit.
Pfam	PF01842. ACT. 1 hit. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_NITMU

Accession

Primary (citable) accession number: Q2Y5Q1

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	December 20, 2005
Last modified:	May 1, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program