Q2XY32 (Q2XY32_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
CG12283 EMBL ABA86436.1

Gene names

Name:

kek1 FlyBase FBgn0015399

Organism

Drosophila melanogaster (Fruit fly) EMBL ABA86436.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	864 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 LRRCT domain. SAAS SAAS000483

Ontologies

Keywords
Domain	Immunoglobulin domain SAAS SAAS000483 Leucine-rich repeat SAAS SAAS000483 Repeat SAAS SAAS000483
PTM	Disulfide bond SAAS SAAS000483
Gene Ontology (GO)
Biological process	cytokinesis Inferred from mutant phenotype. Source: FlyBase negative regulation of epidermal growth factor-activated receptor activity Traceable author statement. Source: FlyBase oogenesis Inferred from mutant phenotype. Source: FlyBase
Cellular component	integral to membrane Traceable author statement. Source: FlyBase
Molecular function	epidermal growth factor binding Inferred from physical interaction. Source: FlyBase
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL ABA86436.1
	Non-terminal residue	864	1	EMBL ABA86436.1

Sequences

	Sequence		Length	Mass (Da)
	Q2XY32 [UniParc]. Last modified December 20, 2005. Version 1. Checksum: 69F190F57A64DA81	FASTA	864	92,754
	10 20 30 40 50 60 LVLTLLPGMI LGTRYNQLHL YANGGASSSG PGGYRPAPSS QNEVYSIADS QPMTEDGYMP 70 80 90 100 110 120 PSQHFPPTHS DLDPPAQQQS TCQTVCACKW KGGKQTVECI DRHLIQIPEH IDPNTQVLDM 130 140 150 160 170 180 SGNKLQTLSN EQFIRANLLN LQKLYLRNCK IGEIERETFK GLTNLVELDL SHNLLVTVPS 190 200 210 220 230 240 LALGHIPSLR ELTLASNHIH KIESQAFGNT PSLHKLDLSH CDIQTISAQA FGGLQGLTLL 250 260 270 280 290 300 RLNGNKLSEL LPKTIETLSR LHGIELHDNP WLCDCRLRDT KLWLMKRNIP YPVAPVCSGG 310 320 330 340 350 360 PERIIDRSFA DLHVDEFACR PEMLPISHYV EAAMGENASI TCRARAVPAA NINWYWNGRL 370 380 390 400 410 420 LANNSAFTAY QRIHMLEQVE GGFEKRSKLV LTNAQETDSS EFYCVAENRA GMAEANFTLH 430 440 450 460 470 480 VSMRAAGMAS LGSGQIVGLS AALVALIVFA LGVIMCLLLR VKRQPYVDSK TPNHMEVITS 490 500 510 520 530 540 VNHQNSITNK TQPATGNGSI GGVVIANGAV ANIIDGGVVQ GGTLERKSSG RGGVPHGVHD 550 560 570 580 590 600 QRSANPVQKP PRLTDLPYST QGYDNNGSVL STASCFISPS GSTGNGGNNP DLINDTKRFG 610 620 630 640 650 660 SDEFADLKIP PISGVGVGGS GEYSRANGCD SLYPSGLWEH GAPVGTTSAD DLFMKRYTDK 670 680 690 700 710 720 TPIIDSTQLY DLHERTAATD YFSKTFPRSH LQQGMMTGGG GGTSTASTVT TNLSGGSSSG 730 740 750 760 770 780 YPNDYGLPLV PGAEHQHNHQ LQMHPLQQLQ QQLTSTLNHQ KQEGSSTGSS PHFSSRTLPR 790 800 810 820 830 840 LHEGSGGGGS SRSSPTPAVS GGHANQAANP STSSSSCSIL PNGQPINAKT IRVWQKGGVP 850 860 VLPPVTALKR ALISSSRNSP DEGY

References

[1]	"Intragenic Hill-Robertson interference influences selection intensity on synonymous mutations in Drosophila." Comeron J.M., Guthrie T.B. Mol. Biol. Evol. 22:2519-2530(2005) [PubMed: 16120803] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Ral1 EMBL ABA86436.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DQ138830 Genomic DNA. Translation: ABA86436.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q2XY32.
Proteomic databases
PRIDE	Q2XY32.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0015399. kek1.
Phylogenomic databases
InParanoid	Q2XY32.
Gene expression databases
ArrayExpress	Q2XY32.
Bgee	Q2XY32.
Family and domain databases
InterPro	IPR000483. Cys-rich_flank_reg_C. IPR007110. Ig-like. IPR013783. Ig-like_fold. IPR013098. Ig_I-set. IPR003598. Ig_sub2. IPR001611. Leu-rich_rpt. IPR003591. Leu-rich_rpt_typical-subtyp. [Graphical view]
Gene3D	G3DSA:2.60.40.10. Ig-like_fold. 1 hit.
Pfam	PF07679. I-set. 1 hit. PF00560. LRR_1. 2 hits. [Graphical view]
SMART	SM00408. IGc2. 1 hit. SM00369. LRR_TYP. 1 hit. SM00082. LRRCT. 1 hit. [Graphical view]
PROSITE	PS50835. IG_LIKE. 1 hit. PS51450. LRR. 6 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2XY32_DROME

Accession

Primary (citable) accession number: Q2XY32

Entry history

Integrated into UniProtKB/TrEMBL:	December 20, 2005
Last sequence update:	December 20, 2005
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)