Unreviewed, UniProtKB/TrEMBL Q2XXS4 (Q2XXS4_DROME)

Names and origin

Protein names

Submitted name:
    CG8896 EMBL ABA86544.1

Gene names

Name:

18w FlyBase FBgn0004364

Organism

Drosophila melanogaster (Fruit fly) EMBL ABA86544.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1374 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 TIR domain. Spearmint SPM000157

Ontologies

Keywords
Cellular component	Membrane
Domain	Leucine-rich repeat Spearmint SPM003591 Repeat Spearmint SPM003591 Transmembrane Spearmint SPM000157
Gene Ontology (GO)
Biological process	antibacterial humoral response Inferred from mutant phenotype. Source: FlyBase cell adhesion Inferred from direct assay. Source: FlyBase embryonic morphogenesis Traceable author statement. Source: FlyBase innate immune response Inferred from electronic annotation. Source: InterPro signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from direct assay. Source: FlyBase intrinsic to membrane Inferred from electronic annotation. Source: InterPro membrane fraction Inferred from direct assay. Source: FlyBase plasma membrane Inferred from direct assay. Source: FlyBase
Molecular function	protein binding Inferred from electronic annotation. Source: InterPro transmembrane receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL ABA86544.1
	Non-terminal residue	1374	1	EMBL ABA86544.1

Sequences

	Sequence		Length	Mass (Da)
	Q2XXS4-1 [UniParc]. Last modified December 20, 2005. Version 1. Checksum: E3FEFE76CE37245C	FASTA	1,374	153,772
	10 20 30 40 50 60 ITIIAVAACL LLLVADAHAQ QQCNWQYGLT TMDIRCSVRA LESGTGTPLD LQVAEAAGRL 70 80 90 100 110 120 DLQCSQELLH ASELAPGLFR QLQKLSELRI DACKLQRVPP NAFEGLMSLK RLTLESHNAV 130 140 150 160 170 180 WGPGKTLELH GQSFQGLKEL SELHLGDNNI RQLPEGVWCS MPSLQLLNLT QNRIRSAEFL 190 200 210 220 230 240 GFSEKLCAGS ALSNANGAVS GGSELQTLDV SFNELRSLPD AWGASRLRRL QTLSLQHNNI 250 260 270 280 290 300 STLAPNALAG LSSLRVLNIS YNHLVSLPSE AFAGNKELRE LHLQGNDLYE LPKGLLHRLE 310 320 330 340 350 360 QLLVLDLSGN QLTSHHVDNS TFAGLIRLIV LNLSNNALTR IGSKTFKELY FLQILDMRNN 370 380 390 400 410 420 SIGHIEEGAF LPLYNLHTLN LAENRLHTLD NRIFNGLYVL TKLTLNNNLV SIVESQAFRN 430 440 450 460 470 480 CSDLKELDLS SNQLTEVPEA VQDLSMLKTL DLGENQISEF KNNTFRNLNQ LTGLRLIDNR 490 500 510 520 530 540 IGNITVGMFQ DLPRLSVLNL AKNRIQSIER GAFDKNTEIE AIRLDKNFLT DINGIFATLA 550 560 570 580 590 600 SLLWLNLSEN HLVWFDYAFI PSNLKWLDIH GNYIEALGNY YKLQEEIRVT TLDASHNRIT 610 620 630 640 650 660 EIGAMSVPNS IELLFINNNI IGQIQANTFV DKTRLARVDL YANVLSKISL NALRVAPVSA 670 680 690 700 710 720 EKPVPEFYLG GNPFECDCSM EWLQRINNLT TRQHPHVVDL GNIECLMPHS RSAPLRPLAS 730 740 750 760 770 780 LSASDFVCKY ESHCPPTCHC CEYEQCECEV ICPGNCSCFH DATWATNIVD CGRQDLAALP 790 800 810 820 830 840 NRIPQDVSDL YLDGNNMPEL EVGHLTGRRN LRALYLNASN LMTLQNGSLA QLVNLRVLHL 850 860 870 880 890 900 ENNKLTALEG TEFRSLGLLR ELYLHNNMLT HISNATFEPL VSLEVLRLDN NRLSSLPHLQ 910 920 930 940 950 960 YRHSLQGLTL GRNAWSCRCQ QLRELAQFVS DNAMVVRDAH DIYCLDAGIK RELELIGNLA 970 980 990 1000 1010 1020 NGPDCSDLLD ASASNISSSQ DLAGGYRLPL LAAVLVLIFL VVVLIIVFVF RESVRMWLFA 1030 1040 1050 1060 1070 1080 HYGVRVCEPR FEDAGKLYDA IILHSEKDYE FVCRNIAAEL EHGRPPFRLC IQQRDLPPQA 1090 1100 1110 1120 1130 1140 SHLQLVEGAR ASRKIILVLT RNLLATEWNR IEFRNAFHES LRGLAQKLVI IEETSVSAEA 1150 1160 1170 1180 1190 1200 EDVAELSPYL KSVPSNRLLT CDRYFWEKLR YAIPIELSPR GNNYTLDHHE RFKQPVSPGM 1210 1220 1230 1240 1250 1260 IFRQAPPPPA YYCTEEMEAN YSSATTATPS PRPTRPGGAA RIVDSMPMPM RPPSEHIYHS 1270 1280 1290 1300 1310 1320 IESEYSAYDQ HEALSMIPTG LMHQHQQQQL RLHQQQQQQQ QQRLLQPQFR AMPQQAIPAP 1330 1340 1350 1360 1370 SAPVHLRSGS GLSQASTSTQ STAQASTSAA AAQQQQQQQQ QQQQAAGSEA ANKN

References

[1]	"Intragenic Hill-Robertson interference influences selection intensity on synonymous mutations in Drosophila." Comeron J.M., Guthrie T.B. Mol. Biol. Evol. 22:2519-2530(2005) [PubMed: 16120803] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Ral1 EMBL ABA86544.1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	DQ138938 Genomic DNA. Translation: ABA86544.1.
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	Q2XXS4.
Genome annotation databases
Ensembl	FBgn0004364. Drosophila melanogaster. [Contig view]
Organism-specific databases
FlyBase	FBgn0004364. 18w.
Gene expression databases
ArrayExpress	Q2XXS4.
Family and domain databases
InterPro	IPR004075. IL1_rcpt_1. IPR001611. Leu-rich_rpt. IPR000372. Leu-rich_rpt_Cys-rich-reg_N. IPR003591. Leu-rich_rpt_typical-subtyp. IPR000483. LRR_C. IPR000157. Toll-Interleukin_rcpt. [Graphical view]
Pfam	PF00560. LRR_1. 14 hits. PF01582. TIR. 1 hit. [Graphical view]
PRINTS	PR01537. INTRLKN1R1F.
SMART	SM00369. LRR_TYP. 9 hits. SM00082. LRRCT. 1 hit. SM00013. LRRNT. 1 hit. SM00255. TIR. 1 hit. [Graphical view]
PROSITE	PS50104. TIR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2XXS4_DROME

Accession

Primary (citable) accession number: Q2XXS4

Entry history

Integrated into UniProtKB/TrEMBL:	December 20, 2005
Last sequence update:	December 20, 2005
Last modified:	June 16, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)