Unreviewed, UniProtKB/TrEMBL Q2XQZ0 (Q2XQZ0_HUMAN)

Names and origin

Protein names	Submitted name:     ADAMTS16s alternative splice form EMBL ABB70405.1
Organism	Homo sapiens (Human) EMBL ABB70405.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	570 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location	Secreted. Spearmint SPM001590
Sequence similarities	Contains 1 peptidase M12B domain. RuleBase RU004141V0 Spearmint SPM001590

Ontologies

Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2XQZ0-1 [UniParc]. Last modified December 20, 2005. Version 1. Checksum: 93121D0AF0C3369F	FASTA	570	63,593
	10 20 30 40 50 60 MKPRARGWRG LAALWMLLAQ VAEQAPACAM GPAAAAPGSP SVPRPPPPAE RPGWMEKGEY 70 80 90 100 110 120 DLVSAYEVDH RGDYVSHEIM HHQRRRRAVP VSEVESLHLR LKGSRHDFHM DLRTSSSLVA 130 140 150 160 170 180 PGFIVQTLGK TGTKSVQTLP PEDFCFYQGS LRSHRNSSVA LSTCQGLSGM IRTEEADYFL 190 200 210 220 230 240 RPLPSHLSWK LGRAAQGSSP SHVLYKRSTE PHAPGASEVL VTSRTWELAH QPLHSSDLRL 250 260 270 280 290 300 GLPQKQHFCG RRKKYMPQPP KEDLFILPDE YKSCLRHKRS LLRSHRNEEL NVETLVVVDK 310 320 330 340 350 360 KMMQNHGHEN ITTYVLTILN MVSALFKDGT IGGNINIAIV GLILLEDEQP GLVISHHADH 370 380 390 400 410 420 TLSSFCQWQS GLMGKDGTRH DHAILLTGLD ICSWKNEPCD TLGFAPISGM CSKYRSCTIN 430 440 450 460 470 480 EDTGLGLAFT IAHESGHNFG MIHDGEGNMC KKSEGNIMSP TLAGRNGVFS WSPCSRQYLH 490 500 510 520 530 540 KFLSTAQAIC LADQPKPVKE YKYPEKLPGE LYDANTQCKW QFGEKAKLCM LDFKKDICKA 550 560 570 LWCHRIGRKC ETKFMPAAEG TICGHDMVRS

References

[1]	"FSH stimulates the expression of the ADAMTS-16 protease in mature human ovarian follicles." Gao S., De Geyter C., Kossowska K., Zhang H. Mol. Hum. Reprod. 13:465-471(2007) [PubMed: 17519324] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	DQ266047 mRNA. Translation: ABB70405.1.
RefSeq	NP_620687.2.
UniGene	Hs.661915
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000145536. Homo sapiens. [Contig view]
GeneID	170690.
Organism-specific databases
HGNC	HGNC:17108. ADAMTS16.
GeneCards	Search...
Phylogenomic databases
HOVERGEN	Q2XQZ0.
Gene expression databases
ArrayExpress	Q2XQZ0.
Family and domain databases
InterPro	IPR001590. Peptidase_M12B. IPR002870. Peptidase_M12B_N. [Graphical view]
Pfam	PF01562. Pep_M12B_propep. 1 hit. PF01421. Reprolysin. 1 hit. [Graphical view]
PROSITE	PS50215. ADAM_MEPRO. 1 hit. [Graphical view]
Other Resources
NextBio	89102.

Entry information

Entry name

Q2XQZ0_HUMAN

Accession

Primary (citable) accession number: Q2XQZ0

Entry history

Integrated into UniProtKB/TrEMBL:	December 20, 2005
Last sequence update:	December 20, 2005
Last modified:	November 4, 2008
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)